LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 1694 1615 11099 0.1455 -0.0175
MCF 10A Pelitinib
10
uM
LJP5
 3
I13
 72
hr
 1694 2097 11168 0.1878 0.0815
MCF 10A Luminespib
0.04
uM
LJP5
 1
H18
 72
hr
 1694 1187 11042 0.1075 -0.1233
MCF 10A Luminespib
0.04
uM
LJP5
 2
H18
 72
hr
 1694 1254 11099 0.1130 -0.1050
MCF 10A Luminespib
0.04
uM
LJP5
 3
H18
 72
hr
 1694 1331 11168 0.1192 -0.0849
MCF 10A Luminespib
0.12
uM
LJP5
 1
H17
 72
hr
 1694 1259 11042 0.1140 -0.1040
MCF 10A Luminespib
0.12
uM
LJP5
 2
H17
 72
hr
 1694 1303 11099 0.1174 -0.0923
MCF 10A Luminespib
0.12
uM
LJP5
 3
H17
 72
hr
 1694 1207 11168 0.1081 -0.1172
MCF 10A Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 1694 1201 11042 0.1088 -0.1195
MCF 10A Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 1694 1248 11099 0.1124 -0.1066
MCF 10A Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 1694 1330 11168 0.1191 -0.0851
MCF 10A Luminespib
1.11
uM
LJP5
 1
H15
 72
hr
 1694 1256 11042 0.1137 -0.1048
MCF 10A Luminespib
1.11
uM
LJP5
 2
H15
 72
hr
 1694 1245 11099 0.1122 -0.1074
MCF 10A Luminespib
1.11
uM
LJP5
 3
H15
 72
hr
 1694 1417 11168 0.1269 -0.0636
MCF 10A Luminespib
3.33
uM
LJP5
 1
H14
 72
hr
 1694 1307 11042 0.1184 -0.0915
MCF 10A Luminespib
3.33
uM
LJP5
 2
H14
 72
hr
 1694 1351 11099 0.1217 -0.0801
MCF 10A Luminespib
3.33
uM
LJP5
 3
H14
 72
hr
 1694 1348 11168 0.1207 -0.0806
MCF 10A Luminespib
10
uM
LJP5
 1
H13
 72
hr
 1694 1272 11042 0.1152 -0.1006
MCF 10A Luminespib
10
uM
LJP5
 2
H13
 72
hr
 1694 1376 11099 0.1240 -0.0739
MCF 10A Luminespib
10
uM
LJP5
 3
H13
 72
hr
 1694 1295 11168 0.1160 -0.0941
MCF 10A AZD8330
0.04
uM
LJP5
 1
G24
 72
hr
 1694 2504 11042 0.2268 0.1554
MCF 10A AZD8330
0.04
uM
LJP5
 2
G24
 72
hr
 1694 2602 11099 0.2344 0.1714
MCF 10A AZD8330
0.04
uM
LJP5
 3
G24
 72
hr
 1694 2770 11168 0.2480 0.1980
MCF 10A AZD8330
0.12
uM
LJP5
 1
G23
 72
hr
 1694 2056 11042 0.1862 0.0742
MCF 10A AZD8330
0.12
uM
LJP5
 2
G23
 72
hr
 1694 2537 11099 0.2286 0.1605