LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SNS-032
1.11
uM
LJP6
 3
H15
 72
hr
 1694 294 11121 0.0264 -0.4754
MCF 10A SNS-032
3.33
uM
LJP6
 1
H14
 72
hr
 1694 323 11220 0.0288 -0.4554
MCF 10A SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 1694 287 11309 0.0254 -0.4771
MCF 10A SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 1694 314 11121 0.0282 -0.4626
MCF 10A SNS-032
10
uM
LJP6
 1
H13
 72
hr
 1694 350 11220 0.0312 -0.4391
MCF 10A SNS-032
10
uM
LJP6
 2
H13
 72
hr
 1694 326 11309 0.0288 -0.4522
MCF 10A SNS-032
10
uM
LJP6
 3
H13
 72
hr
 1694 422 11121 0.0379 -0.4007
MCF 10A Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 1694 1526 11220 0.1360 -0.0376
MCF 10A Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 1694 1790 11309 0.1583 0.0203
MCF 10A Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 1694 1864 11121 0.1676 0.0358
MCF 10A Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 1694 1502 11220 0.1339 -0.0432
MCF 10A Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 1694 1730 11309 0.1530 0.0077
MCF 10A Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 1694 1735 11121 0.1560 0.0088
MCF 10A Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 1694 1474 11220 0.1314 -0.0498
MCF 10A Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 1694 1667 11309 0.1474 -0.0059
MCF 10A Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 1694 1968 11121 0.1770 0.0567
MCF 10A Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 1694 1468 11220 0.1308 -0.0512
MCF 10A Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1694 1785 11309 0.1578 0.0192
MCF 10A Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1694 2115 11121 0.1902 0.0851
MCF 10A Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 1694 1863 11220 0.1660 0.0354
MCF 10A Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 1694 1765 11309 0.1561 0.0150
MCF 10A Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 1694 1977 11121 0.1778 0.0585
MCF 10A Afatinib
10
uM
LJP6
 1
G19
 72
hr
 1694 1818 11220 0.1620 0.0262
MCF 10A Afatinib
10
uM
LJP6
 2
G19
 72
hr
 1694 1586 11309 0.1402 -0.0238
MCF 10A Afatinib
10
uM
LJP6
 3
G19
 72
hr
 1694 1888 11121 0.1698 0.0407