LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Lapatinib | 3.33 | uM | LJP6 | 3 | M20 | 72 | hr | 1694 | 8301 | 11121 | 0.7464 | 0.7957 |
| MCF 10A | Lapatinib | 10 | uM | LJP6 | 1 | M19 | 72 | hr | 1694 | 4405 | 11220 | 0.3926 | 0.4195 |
| MCF 10A | Lapatinib | 10 | uM | LJP6 | 2 | M19 | 72 | hr | 1694 | 4743 | 11309 | 0.4194 | 0.4563 |
| MCF 10A | Lapatinib | 10 | uM | LJP6 | 3 | M19 | 72 | hr | 1694 | 4376 | 11121 | 0.3935 | 0.4184 |
| MCF 10A | Sirolimus | 0.04 | uM | LJP6 | 1 | L18 | 72 | hr | 1694 | 12335 | 11220 | 1.0993 | 1.0706 |
| MCF 10A | Sirolimus | 0.04 | uM | LJP6 | 2 | L18 | 72 | hr | 1694 | 12381 | 11309 | 1.0948 | 1.0672 |
| MCF 10A | Sirolimus | 0.04 | uM | LJP6 | 3 | L18 | 72 | hr | 1694 | 12018 | 11121 | 1.0806 | 1.0580 |
| MCF 10A | Sirolimus | 0.12 | uM | LJP6 | 1 | L17 | 72 | hr | 1694 | 12403 | 11220 | 1.1053 | 1.0748 |
| MCF 10A | Sirolimus | 0.12 | uM | LJP6 | 2 | L17 | 72 | hr | 1694 | 12573 | 11309 | 1.1117 | 1.0789 |
| MCF 10A | Sirolimus | 0.12 | uM | LJP6 | 3 | L17 | 72 | hr | 1694 | 12039 | 11121 | 1.0825 | 1.0593 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 1 | L16 | 72 | hr | 1694 | 12413 | 11220 | 1.1062 | 1.0754 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 2 | L16 | 72 | hr | 1694 | 12672 | 11309 | 1.1205 | 1.0848 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 3 | L16 | 72 | hr | 1694 | 12517 | 11121 | 1.1255 | 1.0890 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 1 | L15 | 72 | hr | 1694 | 12264 | 11220 | 1.0930 | 1.0663 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 2 | L15 | 72 | hr | 1694 | 12668 | 11309 | 1.1201 | 1.0846 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 3 | L15 | 72 | hr | 1694 | 12507 | 11121 | 1.1246 | 1.0884 |
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 1 | L14 | 72 | hr | 1694 | 12547 | 11220 | 1.1182 | 1.0836 |
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 2 | L14 | 72 | hr | 1694 | 12883 | 11309 | 1.1391 | 1.0974 |
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 3 | L14 | 72 | hr | 1694 | 12682 | 11121 | 1.1404 | 1.0991 |
| MCF 10A | Sirolimus | 10 | uM | LJP6 | 1 | L13 | 72 | hr | 1694 | 12294 | 11220 | 1.0956 | 1.0681 |
| MCF 10A | Sirolimus | 10 | uM | LJP6 | 2 | L13 | 72 | hr | 1694 | 12630 | 11309 | 1.1168 | 1.0823 |
| MCF 10A | Sirolimus | 10 | uM | LJP6 | 3 | L13 | 72 | hr | 1694 | 12399 | 11121 | 1.1149 | 1.0818 |
| MCF 10A | ZSTK474 | 0.04 | uM | LJP6 | 1 | M18 | 72 | hr | 1694 | 10958 | 11220 | 0.9766 | 0.9827 |
| MCF 10A | ZSTK474 | 0.04 | uM | LJP6 | 2 | M18 | 72 | hr | 1694 | 11292 | 11309 | 0.9985 | 0.9989 |
| MCF 10A | ZSTK474 | 0.04 | uM | LJP6 | 3 | M18 | 72 | hr | 1694 | 10626 | 11121 | 0.9555 | 0.9667 |