LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | R406 | 10 | uM | LJP6 | 1 | C13 | 72 | hr | 1694 | 8883 | 11220 | 0.7917 | 0.8358 |
| MCF 10A | R406 | 10 | uM | LJP6 | 2 | C13 | 72 | hr | 1694 | 8001 | 11309 | 0.7075 | 0.7626 |
| MCF 10A | R406 | 10 | uM | LJP6 | 3 | C13 | 72 | hr | 1694 | 9137 | 11121 | 0.8216 | 0.8603 |
| MCF 10A | BI-2536 | 0.04 | uM | LJP6 | 1 | D18 | 72 | hr | 1694 | 1093 | 11220 | 0.0974 | -0.1485 |
| MCF 10A | BI-2536 | 0.04 | uM | LJP6 | 2 | D18 | 72 | hr | 1694 | 1060 | 11309 | 0.0937 | -0.1574 |
| MCF 10A | BI-2536 | 0.04 | uM | LJP6 | 3 | D18 | 72 | hr | 1694 | 894 | 11121 | 0.0804 | -0.2098 |
| MCF 10A | BI-2536 | 0.12 | uM | LJP6 | 1 | D17 | 72 | hr | 1694 | 1057 | 11220 | 0.0942 | -0.1589 |
| MCF 10A | BI-2536 | 0.12 | uM | LJP6 | 2 | D17 | 72 | hr | 1694 | 1183 | 11309 | 0.1046 | -0.1229 |
| MCF 10A | BI-2536 | 0.12 | uM | LJP6 | 3 | D17 | 72 | hr | 1694 | 951 | 11121 | 0.0855 | -0.1916 |
| MCF 10A | BI-2536 | 0.37 | uM | LJP6 | 1 | D16 | 72 | hr | 1694 | 1291 | 11220 | 0.1151 | -0.0949 |
| MCF 10A | BI-2536 | 0.37 | uM | LJP6 | 2 | D16 | 72 | hr | 1694 | 1197 | 11309 | 0.1058 | -0.1191 |
| MCF 10A | BI-2536 | 0.37 | uM | LJP6 | 3 | D16 | 72 | hr | 1694 | 1058 | 11121 | 0.0951 | -0.1593 |
| MCF 10A | BI-2536 | 1.11 | uM | LJP6 | 1 | D15 | 72 | hr | 1694 | 1288 | 11220 | 0.1148 | -0.0956 |
| MCF 10A | BI-2536 | 1.11 | uM | LJP6 | 2 | D15 | 72 | hr | 1694 | 1272 | 11309 | 0.1125 | -0.0994 |
| MCF 10A | BI-2536 | 1.11 | uM | LJP6 | 3 | D15 | 72 | hr | 1694 | 1182 | 11121 | 0.1063 | -0.1242 |
| MCF 10A | BI-2536 | 3.33 | uM | LJP6 | 1 | D14 | 72 | hr | 1694 | 1402 | 11220 | 0.1250 | -0.0671 |
| MCF 10A | BI-2536 | 3.33 | uM | LJP6 | 2 | D14 | 72 | hr | 1694 | 1162 | 11309 | 0.1028 | -0.1286 |
| MCF 10A | BI-2536 | 3.33 | uM | LJP6 | 3 | D14 | 72 | hr | 1694 | 1153 | 11121 | 0.1037 | -0.1322 |
| MCF 10A | BI-2536 | 10 | uM | LJP6 | 1 | D13 | 72 | hr | 1694 | 1527 | 11220 | 0.1361 | -0.0374 |
| MCF 10A | BI-2536 | 10 | uM | LJP6 | 2 | D13 | 72 | hr | 1694 | 1164 | 11309 | 0.1029 | -0.1281 |
| MCF 10A | BI-2536 | 10 | uM | LJP6 | 3 | D13 | 72 | hr | 1694 | 1550 | 11121 | 0.1394 | -0.0323 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 1 | I24 | 72 | hr | 1694 | 10619 | 11220 | 0.9464 | 0.9600 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 2 | I24 | 72 | hr | 1694 | 10606 | 11309 | 0.9378 | 0.9537 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 3 | I24 | 72 | hr | 1694 | 9710 | 11121 | 0.8731 | 0.9025 |
| MCF 10A | A443654 | 0.12 | uM | LJP6 | 1 | I23 | 72 | hr | 1694 | 8554 | 11220 | 0.7623 | 0.8106 |