LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 1 | O03 | 72 | hr | 1389 | 1630 | 5772 | 0.2824 | 0.0809 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 3 | O03 | 72 | hr | 1389 | 1647 | 6038 | 0.2728 | 0.0837 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP6 | 1 | O02 | 72 | hr | 1389 | 1209 | 5147 | 0.2349 | -0.0708 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP6 | 2 | O02 | 72 | hr | 1389 | 1187 | 5447 | 0.2179 | -0.0766 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP6 | 3 | O02 | 72 | hr | 1389 | 1255 | 5740 | 0.2186 | -0.0484 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP5 | 1 | O02 | 72 | hr | 1389 | 1214 | 5772 | 0.2103 | -0.0634 |
| MCF7 | Geldanamycin | 3.33 | uM | LJP5 | 3 | O02 | 72 | hr | 1389 | 1301 | 6038 | 0.2155 | -0.0304 |
| MCF7 | Geldanamycin | 10 | uM | LJP6 | 1 | O01 | 72 | hr | 1389 | 566 | 5147 | 0.1100 | -0.3782 |
| MCF7 | Geldanamycin | 10 | uM | LJP6 | 2 | O01 | 72 | hr | 1389 | 702 | 5447 | 0.1289 | -0.2926 |
| MCF7 | Geldanamycin | 10 | uM | LJP6 | 3 | O01 | 72 | hr | 1389 | 597 | 5740 | 0.1040 | -0.3380 |
| MCF7 | Geldanamycin | 10 | uM | LJP5 | 1 | O01 | 72 | hr | 1389 | 614 | 5772 | 0.1064 | -0.3278 |
| MCF7 | Geldanamycin | 10 | uM | LJP5 | 3 | O01 | 72 | hr | 1389 | 785 | 6038 | 0.1300 | -0.2360 |
| MCF7 | YM 201636 | 0.04 | uM | LJP5 | 1 | N12 | 72 | hr | 1389 | 6399 | 5772 | 1.1085 | 1.1028 |
| MCF7 | YM 201636 | 0.04 | uM | LJP5 | 3 | N12 | 72 | hr | 1389 | 6377 | 6038 | 1.0561 | 1.0521 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 1 | N11 | 72 | hr | 1389 | 5852 | 5772 | 1.0138 | 1.0134 |
| MCF7 | YM 201636 | 0.12 | uM | LJP5 | 3 | N11 | 72 | hr | 1389 | 5518 | 6038 | 0.9138 | 0.9168 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 1 | N10 | 72 | hr | 1389 | 4963 | 5772 | 0.8598 | 0.8582 |
| MCF7 | YM 201636 | 0.37 | uM | LJP5 | 3 | N10 | 72 | hr | 1389 | 5271 | 6038 | 0.8729 | 0.8758 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 1 | N09 | 72 | hr | 1389 | 3514 | 5772 | 0.6088 | 0.5709 |
| MCF7 | YM 201636 | 1.11 | uM | LJP5 | 3 | N09 | 72 | hr | 1389 | 4261 | 6038 | 0.7056 | 0.6967 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 1 | N08 | 72 | hr | 1389 | 2776 | 5772 | 0.4809 | 0.4006 |
| MCF7 | YM 201636 | 3.33 | uM | LJP5 | 3 | N08 | 72 | hr | 1389 | 3435 | 6038 | 0.5689 | 0.5327 |
| MCF7 | YM 201636 | 10 | uM | LJP5 | 1 | N07 | 72 | hr | 1389 | 1497 | 5772 | 0.2593 | 0.0371 |
| MCF7 | YM 201636 | 10 | uM | LJP5 | 3 | N07 | 72 | hr | 1389 | 1693 | 6038 | 0.2804 | 0.0978 |
| MCF7 | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1389 | 6210 | 5772 | 1.0758 | 1.0724 |