LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 765 3182 3151 1.0096 1.0094
Hs 578T Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 765 3144 3152 0.9973 0.9974
Hs 578T Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 765 2845 3140 0.9060 0.9054
Hs 578T Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 765 2929 3151 0.9294 0.9295
Hs 578T Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 765 2785 3152 0.8835 0.8823
Hs 578T Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 765 2159 3140 0.6875 0.6640
Hs 578T Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 765 2191 3151 0.6952 0.6739
Hs 578T Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 765 2120 3152 0.6725 0.6470
Hs 578T Fedratinib
3.33
uM
LJP5
 1
L02
 72
hr
 765 977 3140 0.3111 0.1275
Hs 578T Fedratinib
3.33
uM
LJP5
 2
L02
 72
hr
 765 1012 3151 0.3211 0.1468
Hs 578T Fedratinib
3.33
uM
LJP5
 3
L02
 72
hr
 765 1014 3152 0.3217 0.1479
Hs 578T Fedratinib
10
uM
LJP5
 1
L01
 72
hr
 765 362 3140 0.1153 -0.3074
Hs 578T Fedratinib
10
uM
LJP5
 2
L01
 72
hr
 765 340 3151 0.1079 -0.3277
Hs 578T Fedratinib
10
uM
LJP5
 3
L01
 72
hr
 765 262 3152 0.0831 -0.4082
Hs 578T Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 765 1179 3140 0.3754 0.2365
Hs 578T Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 765 1218 3151 0.3865 0.2557
Hs 578T Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 765 1180 3152 0.3743 0.2363
Hs 578T Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 765 1030 3140 0.3280 0.1572
Hs 578T Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 765 1092 3151 0.3465 0.1903
Hs 578T Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 765 1031 3152 0.3271 0.1573
Hs 578T Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 765 1035 3140 0.3296 0.1599
Hs 578T Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 765 1004 3151 0.3186 0.1423
Hs 578T Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 765 1076 3152 0.3413 0.1817
Hs 578T Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 765 1018 3140 0.3242 0.1505
Hs 578T Trametinib
1.11
uM
LJP5
 2
P21
 72
hr
 765 927 3151 0.2941 0.0986