LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T SNS-032
3.33
uM
LJP6
 1
H14
 72
hr
 765 449 3143 0.1428 -0.2300
Hs 578T SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 765 415 3095 0.1341 -0.2616
Hs 578T SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 765 429 3066 0.1399 -0.2509
Hs 578T SNS-032
10
uM
LJP6
 1
H13
 72
hr
 765 383 3143 0.1218 -0.2878
Hs 578T SNS-032
10
uM
LJP6
 2
H13
 72
hr
 765 419 3095 0.1354 -0.2581
Hs 578T SNS-032
10
uM
LJP6
 3
H13
 72
hr
 765 397 3066 0.1295 -0.2793
Hs 578T Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 765 3036 3143 0.9657 0.9661
Hs 578T Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 765 2861 3095 0.9242 0.9233
Hs 578T Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 765 2902 3066 0.9465 0.9459
Hs 578T Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 765 2933 3143 0.9330 0.9331
Hs 578T Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 765 2811 3095 0.9081 0.9066
Hs 578T Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 765 2885 3066 0.9410 0.9402
Hs 578T Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 765 3034 3143 0.9651 0.9654
Hs 578T Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 765 2795 3095 0.9029 0.9012
Hs 578T Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 765 2822 3066 0.9204 0.9189
Hs 578T Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 765 2800 3143 0.8907 0.8896
Hs 578T Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 765 2671 3095 0.8628 0.8589
Hs 578T Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 765 2657 3066 0.8666 0.8620
Hs 578T Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 765 2466 3143 0.7844 0.7754
Hs 578T Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 765 2484 3095 0.8024 0.7932
Hs 578T Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 765 2638 3066 0.8604 0.8554
Hs 578T Afatinib
10
uM
LJP6
 1
G19
 72
hr
 765 504 3143 0.1603 -0.1851
Hs 578T Afatinib
10
uM
LJP6
 2
G19
 72
hr
 765 458 3095 0.1480 -0.2246
Hs 578T Afatinib
10
uM
LJP6
 3
G19
 72
hr
 765 511 3066 0.1667 -0.1825
Hs 578T GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 765 3019 3143 0.9603 0.9607