LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nilotinib | 0.12 | uM | LJP5 | 3 | N17 | 72 | hr | 1389 | 6361 | 6038 | 1.0534 | 1.0497 |
| MCF7 | Nilotinib | 0.37 | uM | LJP5 | 1 | N16 | 72 | hr | 1389 | 5655 | 5772 | 0.9796 | 0.9801 |
| MCF7 | Nilotinib | 0.37 | uM | LJP5 | 3 | N16 | 72 | hr | 1389 | 5748 | 6038 | 0.9519 | 0.9540 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 1 | N15 | 72 | hr | 1389 | 5580 | 5772 | 0.9667 | 0.9673 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 3 | N15 | 72 | hr | 1389 | 5835 | 6038 | 0.9663 | 0.9679 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 1 | N14 | 72 | hr | 1389 | 5664 | 5772 | 0.9812 | 0.9816 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 3 | N14 | 72 | hr | 1389 | 5503 | 6038 | 0.9113 | 0.9143 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 1 | N13 | 72 | hr | 1389 | 1798 | 5772 | 0.3115 | 0.1338 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 3 | N13 | 72 | hr | 1389 | 1441 | 6038 | 0.2386 | 0.0175 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 1 | K24 | 72 | hr | 1389 | 4270 | 5147 | 0.8296 | 0.8117 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 2 | K24 | 72 | hr | 1389 | 4605 | 5447 | 0.8453 | 0.8366 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 3 | K24 | 72 | hr | 1389 | 3609 | 5740 | 0.6287 | 0.5943 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 1 | K23 | 72 | hr | 1389 | 4472 | 5147 | 0.8688 | 0.8566 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 2 | K23 | 72 | hr | 1389 | 3736 | 5447 | 0.6858 | 0.6517 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 3 | K23 | 72 | hr | 1389 | 3854 | 5740 | 0.6714 | 0.6463 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 1 | K22 | 72 | hr | 1389 | 2432 | 5147 | 0.4725 | 0.3450 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 2 | K22 | 72 | hr | 1389 | 2690 | 5447 | 0.4938 | 0.3982 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 3 | K22 | 72 | hr | 1389 | 2727 | 5740 | 0.4751 | 0.3903 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 1 | K21 | 72 | hr | 1389 | 1297 | 5147 | 0.2520 | -0.0356 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 2 | K21 | 72 | hr | 1389 | 1295 | 5447 | 0.2377 | -0.0349 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 3 | K21 | 72 | hr | 1389 | 1396 | 5740 | 0.2432 | 0.0024 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 1 | K20 | 72 | hr | 1389 | 915 | 5147 | 0.1778 | -0.1982 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 2 | K20 | 72 | hr | 1389 | 921 | 5447 | 0.1691 | -0.1881 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 3 | K20 | 72 | hr | 1389 | 1037 | 5740 | 0.1807 | -0.1331 |
| MCF7 | JNK-9L | 10 | uM | LJP6 | 1 | K19 | 72 | hr | 1389 | 1280 | 5147 | 0.2487 | -0.0423 |