LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T LDN-193189
10
uM
LJP5
 3
G01
 72
hr
 765 197 3152 0.0625 -0.4853
Hs 578T PF431396
0.04
uM
LJP5
 1
E12
 72
hr
 765 2384 3140 0.7592 0.7470
Hs 578T PF431396
0.04
uM
LJP5
 2
E12
 72
hr
 765 2387 3151 0.7574 0.7456
Hs 578T PF431396
0.04
uM
LJP5
 3
E12
 72
hr
 765 2336 3152 0.7410 0.7271
Hs 578T PF431396
0.12
uM
LJP5
 1
E11
 72
hr
 765 2194 3140 0.6987 0.6772
Hs 578T PF431396
0.12
uM
LJP5
 2
E11
 72
hr
 765 2083 3151 0.6609 0.6330
Hs 578T PF431396
0.12
uM
LJP5
 3
E11
 72
hr
 765 2065 3152 0.6551 0.6259
Hs 578T PF431396
0.37
uM
LJP5
 1
E10
 72
hr
 765 1874 3140 0.5968 0.5523
Hs 578T PF431396
0.37
uM
LJP5
 2
E10
 72
hr
 765 1808 3151 0.5737 0.5236
Hs 578T PF431396
0.37
uM
LJP5
 3
E10
 72
hr
 765 1741 3152 0.5523 0.4956
Hs 578T PF431396
1.11
uM
LJP5
 1
E09
 72
hr
 765 1148 3140 0.3656 0.2204
Hs 578T PF431396
1.11
uM
LJP5
 2
E09
 72
hr
 765 1181 3151 0.3747 0.2369
Hs 578T PF431396
1.11
uM
LJP5
 3
E09
 72
hr
 765 1098 3152 0.3483 0.1935
Hs 578T PF431396
3.33
uM
LJP5
 1
E08
 72
hr
 765 941 3140 0.2997 0.1070
Hs 578T PF431396
3.33
uM
LJP5
 2
E08
 72
hr
 765 934 3151 0.2964 0.1026
Hs 578T PF431396
3.33
uM
LJP5
 3
E08
 72
hr
 765 888 3152 0.2817 0.0757
Hs 578T PF431396
10
uM
LJP5
 1
E07
 72
hr
 765 490 3140 0.1560 -0.1964
Hs 578T PF431396
10
uM
LJP5
 2
E07
 72
hr
 765 525 3151 0.1666 -0.1684
Hs 578T PF431396
10
uM
LJP5
 3
E07
 72
hr
 765 453 3152 0.1437 -0.2263
Hs 578T Celastrol
0.04
uM
LJP6
 1
G12
 72
hr
 765 3201 3143 1.0182 1.0178
Hs 578T Celastrol
0.04
uM
LJP6
 2
G12
 72
hr
 765 3178 3095 1.0266 1.0262
Hs 578T Celastrol
0.04
uM
LJP6
 3
G12
 72
hr
 765 3155 3066 1.0290 1.0288
Hs 578T Celastrol
0.12
uM
LJP6
 1
G11
 72
hr
 765 3353 3143 1.0665 1.0642
Hs 578T Celastrol
0.12
uM
LJP6
 2
G11
 72
hr
 765 3176 3095 1.0260 1.0256
Hs 578T Celastrol
0.12
uM
LJP6
 3
G11
 72
hr
 765 3115 3066 1.0160 1.0159