LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 765 1963 3066 0.6403 0.6008
Hs 578T JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 765 860 3143 0.2736 0.0591
Hs 578T JNK-9L
3.33
uM
LJP6
 2
K20
 72
hr
 765 819 3095 0.2646 0.0344
Hs 578T JNK-9L
3.33
uM
LJP6
 3
K20
 72
hr
 765 910 3066 0.2968 0.0905
Hs 578T JNK-9L
10
uM
LJP6
 1
K19
 72
hr
 765 515 3143 0.1638 -0.1764
Hs 578T JNK-9L
10
uM
LJP6
 2
K19
 72
hr
 765 493 3095 0.1593 -0.1958
Hs 578T JNK-9L
10
uM
LJP6
 3
K19
 72
hr
 765 585 3066 0.1908 -0.1254
Hs 578T PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 765 1573 3143 0.5004 0.4241
Hs 578T PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 765 1647 3095 0.5320 0.4626
Hs 578T PD0325901
0.04
uM
LJP6
 3
E06
 72
hr
 765 1696 3066 0.5532 0.4881
Hs 578T PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 765 1689 3140 0.5378 0.4751
Hs 578T PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 765 1676 3151 0.5318 0.4681
Hs 578T PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 765 1704 3152 0.5405 0.4799
Hs 578T PD0325901
0.12
uM
LJP6
 1
E05
 72
hr
 765 1395 3143 0.4437 0.3426
Hs 578T PD0325901
0.12
uM
LJP6
 2
E05
 72
hr
 765 1446 3095 0.4671 0.3712
Hs 578T PD0325901
0.12
uM
LJP6
 3
E05
 72
hr
 765 1358 3066 0.4429 0.3318
Hs 578T PD0325901
0.12
uM
LJP5
 1
C05
 72
hr
 765 1420 3140 0.4522 0.3547
Hs 578T PD0325901
0.12
uM
LJP5
 2
C05
 72
hr
 765 1450 3151 0.4601 0.3676
Hs 578T PD0325901
0.12
uM
LJP5
 3
C05
 72
hr
 765 1436 3152 0.4555 0.3610
Hs 578T PD0325901
0.37
uM
LJP6
 1
E04
 72
hr
 765 1403 3143 0.4463 0.3464
Hs 578T PD0325901
0.37
uM
LJP6
 2
E04
 72
hr
 765 1240 3095 0.4006 0.2706
Hs 578T PD0325901
0.37
uM
LJP6
 3
E04
 72
hr
 765 1256 3066 0.4097 0.2809
Hs 578T PD0325901
0.37
uM
LJP5
 1
C04
 72
hr
 765 1299 3140 0.4137 0.2968
Hs 578T PD0325901
0.37
uM
LJP5
 2
C04
 72
hr
 765 1424 3151 0.4518 0.3555
Hs 578T PD0325901
0.37
uM
LJP5
 3
C04
 72
hr
 765 1324 3152 0.4200 0.3080