LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Vemurafenib
10
uM
LJP5
 3
C13
 72
hr
 765 2009 3152 0.6373 0.6042
Hs 578T Enzastaurin
0.04
uM
LJP5
 1
D18
 72
hr
 765 3139 3140 0.9996 0.9996
Hs 578T Enzastaurin
0.04
uM
LJP5
 2
D18
 72
hr
 765 3198 3151 1.0147 1.0143
Hs 578T Enzastaurin
0.04
uM
LJP5
 3
D18
 72
hr
 765 3045 3152 0.9659 0.9663
Hs 578T Enzastaurin
0.12
uM
LJP5
 1
D17
 72
hr
 765 3045 3140 0.9696 0.9700
Hs 578T Enzastaurin
0.12
uM
LJP5
 2
D17
 72
hr
 765 3117 3151 0.9890 0.9892
Hs 578T Enzastaurin
0.12
uM
LJP5
 3
D17
 72
hr
 765 3073 3152 0.9748 0.9752
Hs 578T Enzastaurin
0.37
uM
LJP5
 1
D16
 72
hr
 765 3123 3140 0.9945 0.9946
Hs 578T Enzastaurin
0.37
uM
LJP5
 2
D16
 72
hr
 765 3084 3151 0.9785 0.9789
Hs 578T Enzastaurin
0.37
uM
LJP5
 3
D16
 72
hr
 765 2947 3152 0.9348 0.9351
Hs 578T Enzastaurin
1.11
uM
LJP5
 1
D15
 72
hr
 765 3161 3140 1.0066 1.0064
Hs 578T Enzastaurin
1.11
uM
LJP5
 2
D15
 72
hr
 765 3142 3151 0.9969 0.9970
Hs 578T Enzastaurin
1.11
uM
LJP5
 3
D15
 72
hr
 765 3026 3152 0.9599 0.9603
Hs 578T Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 765 3134 3140 0.9980 0.9980
Hs 578T Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 765 3055 3151 0.9693 0.9697
Hs 578T Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 765 3216 3152 1.0202 1.0196
Hs 578T Enzastaurin
10
uM
LJP5
 1
D13
 72
hr
 765 3040 3140 0.9680 0.9684
Hs 578T Enzastaurin
10
uM
LJP5
 2
D13
 72
hr
 765 3033 3151 0.9624 0.9628
Hs 578T Enzastaurin
10
uM
LJP5
 3
D13
 72
hr
 765 3056 3152 0.9694 0.9698
Hs 578T Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 765 2307 3143 0.7338 0.7183
Hs 578T Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 765 2260 3095 0.7301 0.7111
Hs 578T Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 765 2250 3066 0.7339 0.7137
Hs 578T Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 765 2011 3143 0.6397 0.6064
Hs 578T Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 765 1926 3095 0.6222 0.5806
Hs 578T Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 765 1901 3066 0.6200 0.5754