LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 765 2099 3152 0.6658 0.6390
Hs 578T NU7441
10
uM
LJP5
 1
C07
 72
hr
 765 1189 3140 0.3786 0.2416
Hs 578T NU7441
10
uM
LJP5
 2
C07
 72
hr
 765 1222 3151 0.3877 0.2577
Hs 578T NU7441
10
uM
LJP5
 3
C07
 72
hr
 765 1138 3152 0.3610 0.2146
Hs 578T OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 765 2809 3143 0.8935 0.8925
Hs 578T OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 765 2905 3095 0.9384 0.9379
Hs 578T OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 765 2911 3066 0.9495 0.9489
Hs 578T OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 765 2847 3143 0.9056 0.9051
Hs 578T OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 765 2671 3095 0.8628 0.8589
Hs 578T OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 765 2781 3066 0.9071 0.9049
Hs 578T OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 765 2531 3143 0.8051 0.7982
Hs 578T OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 765 2366 3095 0.7643 0.7504
Hs 578T OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 765 2333 3066 0.7609 0.7450
Hs 578T OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 765 1703 3143 0.5417 0.4806
Hs 578T OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 765 1545 3095 0.4991 0.4170
Hs 578T OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 765 1434 3066 0.4677 0.3685
Hs 578T OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 765 1154 3143 0.3671 0.2234
Hs 578T OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 765 1204 3095 0.3889 0.2522
Hs 578T OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 765 1137 3066 0.3708 0.2188
Hs 578T OSI-027
10
uM
LJP6
 1
E07
 72
hr
 765 820 3143 0.2608 0.0346
Hs 578T OSI-027
10
uM
LJP6
 2
E07
 72
hr
 765 888 3095 0.2869 0.0767
Hs 578T OSI-027
10
uM
LJP6
 3
E07
 72
hr
 765 939 3066 0.3063 0.1077
Hs 578T WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 765 1103 3143 0.3509 0.1965
Hs 578T WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 765 1064 3095 0.3437 0.1777
Hs 578T WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 765 1087 3066 0.3545 0.1917