LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T BX-912
1.11
uM
LJP5
 3
L21
 72
hr
 765 1612 3152 0.5114 0.4403
Hs 578T BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 765 763 3140 0.2430 -0.0013
Hs 578T BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 765 952 3151 0.3021 0.1130
Hs 578T BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 765 1032 3152 0.3274 0.1578
Hs 578T BX-912
10
uM
LJP5
 1
L19
 72
hr
 765 413 3140 0.1315 -0.2611
Hs 578T BX-912
10
uM
LJP5
 2
L19
 72
hr
 765 439 3151 0.1393 -0.2381
Hs 578T BX-912
10
uM
LJP5
 3
L19
 72
hr
 765 394 3152 0.1250 -0.2774
Hs 578T Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 765 2112 3143 0.6718 0.6455
Hs 578T Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 765 2068 3095 0.6680 0.6374
Hs 578T Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 765 2035 3066 0.6637 0.6299
Hs 578T Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 765 1845 3143 0.5869 0.5400
Hs 578T Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 765 1633 3095 0.5275 0.4564
Hs 578T Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 765 1748 3066 0.5701 0.5107
Hs 578T Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 765 1641 3143 0.5220 0.4540
Hs 578T Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 765 1579 3095 0.5101 0.4324
Hs 578T Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 765 1584 3066 0.5166 0.4382
Hs 578T Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 765 1532 3143 0.4873 0.4058
Hs 578T Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 765 1461 3095 0.4720 0.3782
Hs 578T Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 765 1460 3066 0.4762 0.3808
Hs 578T Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 765 1409 3143 0.4482 0.3492
Hs 578T Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 765 1349 3095 0.4358 0.3248
Hs 578T Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 765 1325 3066 0.4322 0.3155
Hs 578T Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 765 1129 3143 0.3591 0.2103
Hs 578T Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 765 1114 3095 0.3599 0.2048
Hs 578T Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 765 1063 3066 0.3467 0.1785