LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 1334 1458 4051 0.3599 0.0567
BT-20 Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 1334 1333 4117 0.3237 -0.0008
BT-20 Dactolisib
10
uM
LJP5
 1
M13
 72
hr
 1334 1543 3930 0.3925 0.0975
BT-20 Dactolisib
10
uM
LJP5
 2
M13
 72
hr
 1334 1390 4051 0.3431 0.0257
BT-20 Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 1334 1380 4117 0.3351 0.0208
BT-20 Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 1334 4050 3930 1.0303 1.0387
BT-20 Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 1334 4276 4051 1.0555 1.0686
BT-20 Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 1334 4053 4117 0.9843 0.9806
BT-20 Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 1334 3918 3930 0.9968 0.9958
BT-20 Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 1334 4272 4051 1.0545 1.0674
BT-20 Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 1334 4111 4117 0.9984 0.9980
BT-20 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 1334 3157 3930 0.8032 0.7375
BT-20 Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 1334 3259 4051 0.8045 0.7460
BT-20 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1334 3325 4117 0.8075 0.7535
BT-20 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1334 2787 3930 0.7090 0.6040
BT-20 Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 1334 3134 4051 0.7736 0.7039
BT-20 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 1334 3050 4117 0.7407 0.6628
BT-20 Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 1334 1730 3930 0.4401 0.1811
BT-20 Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 1334 1671 4051 0.4125 0.1506
BT-20 Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 1334 1593 4117 0.3869 0.1150
BT-20 Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 1334 893 3930 0.2272 -0.2273
BT-20 Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 1334 922 4051 0.2276 -0.2062
BT-20 Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 1334 936 4117 0.2273 -0.1961
BT-20 GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 1334 2438 3930 0.6202 0.4720
BT-20 GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 1334 2370 4051 0.5850 0.4311