LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 1334 1645 4117 0.3995 0.1373
BT-20 Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 1334 1118 3930 0.2844 -0.1075
BT-20 Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 1334 1243 4051 0.3068 -0.0435
BT-20 Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 1334 1357 4117 0.3296 0.0103
BT-20 Barasertib
10
uM
LJP5
 1
D07
 72
hr
 1334 941 3930 0.2394 -0.2009
BT-20 Barasertib
10
uM
LJP5
 2
D07
 72
hr
 1334 984 4051 0.2429 -0.1733
BT-20 Barasertib
10
uM
LJP5
 3
D07
 72
hr
 1334 1074 4117 0.2608 -0.1251
BT-20 Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 1334 3410 3930 0.8675 0.8257
BT-20 Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 1334 3913 4051 0.9659 0.9572
BT-20 Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 1334 4169 4117 1.0125 1.0153
BT-20 Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1334 3523 3930 0.8963 0.8643
BT-20 Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1334 3809 4051 0.9403 0.9245
BT-20 Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1334 4094 4117 0.9943 0.9929
BT-20 Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 1334 3598 3930 0.9153 0.8896
BT-20 Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 1334 4081 4051 1.0074 1.0092
BT-20 Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 1334 4244 4117 1.0307 1.0375
BT-20 Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 1334 3617 3930 0.9202 0.8960
BT-20 Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 1334 4227 4051 1.0434 1.0538
BT-20 Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 1334 4007 4117 0.9731 0.9668
BT-20 Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 1334 3180 3930 0.8090 0.7457
BT-20 Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 1334 3623 4051 0.8943 0.8653
BT-20 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1334 3984 4117 0.9675 0.9598
BT-20 Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 1334 2633 3930 0.6698 0.5465
BT-20 Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 1334 2654 4051 0.6551 0.5359
BT-20 Vemurafenib
10
uM
LJP5
 3
C13
 72
hr
 1334 3008 4117 0.7305 0.6486