LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 1334 3649 3930 0.9283 0.9068
BT-20 BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 1334 3386 4051 0.8358 0.7882
BT-20 BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 1334 3700 4117 0.8986 0.8726
BT-20 BX-912
10
uM
LJP5
 1
L19
 72
hr
 1334 1962 3930 0.4991 0.2805
BT-20 BX-912
10
uM
LJP5
 2
L19
 72
hr
 1334 1917 4051 0.4732 0.2536
BT-20 BX-912
10
uM
LJP5
 3
L19
 72
hr
 1334 1780 4117 0.4323 0.1938
BT-20 Selumetinib
0.04
uM
LJP6
 1
M12
 72
hr
 1334 4726 3955 1.1947 1.2404
BT-20 Selumetinib
0.04
uM
LJP6
 2
M12
 72
hr
 1334 4350 3899 1.1156 1.1466
BT-20 Selumetinib
0.04
uM
LJP6
 3
M12
 72
hr
 1334 4157 3921 1.0601 1.0765
BT-20 Selumetinib
0.12
uM
LJP6
 1
M11
 72
hr
 1334 4514 3955 1.1411 1.1757
BT-20 Selumetinib
0.12
uM
LJP6
 2
M11
 72
hr
 1334 3979 3899 1.0205 1.0264
BT-20 Selumetinib
0.12
uM
LJP6
 3
M11
 72
hr
 1334 4339 3921 1.1065 1.1345
BT-20 Selumetinib
0.37
uM
LJP6
 1
M10
 72
hr
 1334 4097 3955 1.0357 1.0453
BT-20 Selumetinib
0.37
uM
LJP6
 2
M10
 72
hr
 1334 3459 3899 0.8871 0.8510
BT-20 Selumetinib
0.37
uM
LJP6
 3
M10
 72
hr
 1334 3990 3921 1.0175 1.0224
BT-20 Selumetinib
1.11
uM
LJP6
 1
M09
 72
hr
 1334 4190 3955 1.0592 1.0748
BT-20 Selumetinib
1.11
uM
LJP6
 2
M09
 72
hr
 1334 3873 3899 0.9933 0.9913
BT-20 Selumetinib
1.11
uM
LJP6
 3
M09
 72
hr
 1334 3577 3921 0.9122 0.8852
BT-20 Selumetinib
3.33
uM
LJP6
 1
M08
 72
hr
 1334 4051 3955 1.0241 1.0306
BT-20 Selumetinib
3.33
uM
LJP6
 2
M08
 72
hr
 1334 3668 3899 0.9407 0.9225
BT-20 Selumetinib
3.33
uM
LJP6
 3
M08
 72
hr
 1334 3562 3921 0.9084 0.8801
BT-20 Selumetinib
10
uM
LJP6
 1
M07
 72
hr
 1334 4219 3955 1.0665 1.0839
BT-20 Selumetinib
10
uM
LJP6
 2
M07
 72
hr
 1334 4106 3899 1.0531 1.0680
BT-20 Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 1334 3757 3921 0.9581 0.9457
BT-20 MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 1334 4191 3955 1.0595 1.0751