LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 1389 3680 5147 0.7150 0.6746
MCF7 OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 1389 4551 5447 0.8354 0.8256
MCF7 OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 1389 3820 5740 0.6655 0.6392
MCF7 OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1389 2596 5147 0.5044 0.3923
MCF7 OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1389 2980 5447 0.5470 0.4728
MCF7 OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1389 2970 5740 0.5174 0.4495
MCF7 OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 1389 2044 5147 0.3971 0.2268
MCF7 OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 1389 2170 5447 0.3983 0.2539
MCF7 OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 1389 2311 5740 0.4026 0.2823
MCF7 OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 1389 2029 5147 0.3942 0.2220
MCF7 OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 1389 2180 5447 0.4002 0.2568
MCF7 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 1389 2216 5740 0.3860 0.2563
MCF7 OSI-027
10
uM
LJP6
 1
E07
 72
hr
 1389 1852 5147 0.3598 0.1644
MCF7 OSI-027
10
uM
LJP6
 2
E07
 72
hr
 1389 1956 5447 0.3590 0.1896
MCF7 OSI-027
10
uM
LJP6
 3
E07
 72
hr
 1389 1876 5740 0.3268 0.1581
MCF7 WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 1389 2101 5147 0.4082 0.2448
MCF7 WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 1389 1974 5447 0.3623 0.1951
MCF7 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1389 1801 5740 0.3137 0.1353
MCF7 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1389 1995 5147 0.3876 0.2112
MCF7 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1389 1794 5447 0.3293 0.1386
MCF7 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1389 1968 5740 0.3428 0.1855
MCF7 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1389 1896 5147 0.3684 0.1790
MCF7 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1389 1871 5447 0.3434 0.1631
MCF7 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1389 1796 5740 0.3129 0.1337
MCF7 WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 1389 1955 5147 0.3798 0.1983