LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1334 1136 4117 0.2759 -0.0944
BT-20 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 1334 1001 3930 0.2547 -0.1686
BT-20 Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 1334 1030 4051 0.2543 -0.1494
BT-20 Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 1334 978 4117 0.2375 -0.1741
BT-20 Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 1334 1040 3930 0.2646 -0.1479
BT-20 Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 1334 1024 4051 0.2528 -0.1525
BT-20 Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 1334 1011 4117 0.2455 -0.1571
BT-20 Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 1334 1068 3930 0.2717 -0.1333
BT-20 Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 1334 1017 4051 0.2510 -0.1561
BT-20 Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 1334 1061 4117 0.2577 -0.1317
BT-20 Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 1334 3352 3955 0.8474 0.7995
BT-20 Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 1334 3825 3899 0.9810 0.9753
BT-20 Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 1334 4315 3921 1.1004 1.1269
BT-20 Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 1334 3253 3955 0.8223 0.7654
BT-20 Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 1334 3991 3899 1.0236 1.0303
BT-20 Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 1334 3938 3921 1.0042 1.0055
BT-20 Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 1334 3501 3955 0.8850 0.8501
BT-20 Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 1334 3917 3899 1.0046 1.0059
BT-20 Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 1334 3977 3921 1.0142 1.0182
BT-20 Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 1334 3343 3955 0.8451 0.7964
BT-20 Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 1334 4220 3899 1.0823 1.1049
BT-20 Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 1334 4043 3921 1.0310 1.0397
BT-20 Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 1334 3895 3955 0.9846 0.9803
BT-20 Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 1334 3985 3899 1.0220 1.0284
BT-20 Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 1334 3900 3921 0.9946 0.9930