LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Selumetinib | 3.33 | uM | LJP6 | 2 | M08 | 72 | hr | 1389 | 2994 | 5447 | 0.5496 | 0.4763 |
| MCF7 | Selumetinib | 3.33 | uM | LJP6 | 3 | M08 | 72 | hr | 1389 | 3243 | 5740 | 0.5649 | 0.5131 |
| MCF7 | Selumetinib | 10 | uM | LJP6 | 1 | M07 | 72 | hr | 1389 | 3445 | 5147 | 0.6693 | 0.6172 |
| MCF7 | Selumetinib | 10 | uM | LJP6 | 2 | M07 | 72 | hr | 1389 | 2860 | 5447 | 0.5250 | 0.4424 |
| MCF7 | Selumetinib | 10 | uM | LJP6 | 3 | M07 | 72 | hr | 1389 | 2910 | 5740 | 0.5069 | 0.4351 |
| MCF7 | MK2206 | 0.04 | uM | LJP6 | 1 | F06 | 72 | hr | 1389 | 3872 | 5147 | 0.7523 | 0.7203 |
| MCF7 | MK2206 | 0.04 | uM | LJP6 | 2 | F06 | 72 | hr | 1389 | 4261 | 5447 | 0.7821 | 0.7656 |
| MCF7 | MK2206 | 0.04 | uM | LJP6 | 3 | F06 | 72 | hr | 1389 | 4080 | 5740 | 0.7107 | 0.6927 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 1 | F05 | 72 | hr | 1389 | 3246 | 5147 | 0.6307 | 0.5670 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 2 | F05 | 72 | hr | 1389 | 3606 | 5447 | 0.6619 | 0.6223 |
| MCF7 | MK2206 | 0.12 | uM | LJP6 | 3 | F05 | 72 | hr | 1389 | 3682 | 5740 | 0.6414 | 0.6100 |
| MCF7 | MK2206 | 0.37 | uM | LJP6 | 1 | F04 | 72 | hr | 1389 | 2203 | 5147 | 0.4280 | 0.2764 |
| MCF7 | MK2206 | 0.37 | uM | LJP6 | 2 | F04 | 72 | hr | 1389 | 2442 | 5447 | 0.4482 | 0.3313 |
| MCF7 | MK2206 | 0.37 | uM | LJP6 | 3 | F04 | 72 | hr | 1389 | 2461 | 5740 | 0.4287 | 0.3223 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 1 | F03 | 72 | hr | 1389 | 2756 | 5147 | 0.5355 | 0.4370 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 2 | F03 | 72 | hr | 1389 | 2692 | 5447 | 0.4941 | 0.3988 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 3 | F03 | 72 | hr | 1389 | 2848 | 5740 | 0.4961 | 0.4201 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 1 | F02 | 72 | hr | 1389 | 2149 | 5147 | 0.4175 | 0.2598 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 2 | F02 | 72 | hr | 1389 | 2241 | 5447 | 0.4114 | 0.2746 |
| MCF7 | MK2206 | 3.33 | uM | LJP6 | 3 | F02 | 72 | hr | 1389 | 2243 | 5740 | 0.3907 | 0.2638 |
| MCF7 | MK2206 | 10 | uM | LJP6 | 1 | F01 | 72 | hr | 1389 | 1434 | 5147 | 0.2786 | 0.0170 |
| MCF7 | MK2206 | 10 | uM | LJP6 | 2 | F01 | 72 | hr | 1389 | 1244 | 5447 | 0.2283 | -0.0544 |
| MCF7 | MK2206 | 10 | uM | LJP6 | 3 | F01 | 72 | hr | 1389 | 1683 | 5740 | 0.2932 | 0.0983 |
| MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 1 | I06 | 72 | hr | 1389 | 5815 | 5772 | 1.0074 | 1.0072 |
| MCF7 | AZD-6482 | 0.04 | uM | LJP5 | 3 | I06 | 72 | hr | 1389 | 6353 | 6038 | 1.0521 | 1.0485 |