LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 1 | A23 | 72 | hr | 1389 | 4053 | 5772 | 0.7021 | 0.6838 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 3 | A23 | 72 | hr | 1389 | 5108 | 6038 | 0.8459 | 0.8482 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 1 | A22 | 72 | hr | 1389 | 3953 | 5772 | 0.6848 | 0.6635 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 3 | A22 | 72 | hr | 1389 | 4458 | 6038 | 0.7383 | 0.7333 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 1 | A21 | 72 | hr | 1389 | 2672 | 5772 | 0.4629 | 0.3748 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 3 | A21 | 72 | hr | 1389 | 3898 | 6038 | 0.6455 | 0.6269 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 1 | A20 | 72 | hr | 1389 | 1179 | 5772 | 0.2042 | -0.0767 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 3 | A20 | 72 | hr | 1389 | 2310 | 6038 | 0.3826 | 0.2711 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 1 | A19 | 72 | hr | 1389 | 908 | 5772 | 0.1573 | -0.1869 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 3 | A19 | 72 | hr | 1389 | 1250 | 6038 | 0.2070 | -0.0485 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 1 | D06 | 72 | hr | 1389 | 5734 | 5147 | 1.1140 | 1.1176 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 2 | D06 | 72 | hr | 1389 | 5195 | 5447 | 0.9536 | 0.9524 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 3 | D06 | 72 | hr | 1389 | 5386 | 5740 | 0.9383 | 0.9387 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 1 | D05 | 72 | hr | 1389 | 5321 | 5147 | 1.0338 | 1.0355 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 2 | D05 | 72 | hr | 1389 | 4933 | 5447 | 0.9055 | 0.9018 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 3 | D05 | 72 | hr | 1389 | 5305 | 5740 | 0.9241 | 0.9244 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 1 | D04 | 72 | hr | 1389 | 5618 | 5147 | 1.0915 | 1.0948 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 2 | D04 | 72 | hr | 1389 | 4553 | 5447 | 0.8357 | 0.8260 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 3 | D04 | 72 | hr | 1389 | 4822 | 5740 | 0.8400 | 0.8367 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 1 | D03 | 72 | hr | 1389 | 4085 | 5147 | 0.7937 | 0.7698 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 2 | D03 | 72 | hr | 1389 | 3227 | 5447 | 0.5923 | 0.5335 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 3 | D03 | 72 | hr | 1389 | 3688 | 5740 | 0.6425 | 0.6112 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 1 | D02 | 72 | hr | 1389 | 1605 | 5147 | 0.3118 | 0.0795 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 2 | D02 | 72 | hr | 1389 | 1360 | 5447 | 0.2496 | -0.0107 |
| MCF7 | BMS345541 | 3.33 | uM | LJP6 | 3 | D02 | 72 | hr | 1389 | 1816 | 5740 | 0.3164 | 0.1399 |