LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 1 | H10 | 72 | hr | 2543 | 2806 | 5734 | 0.4893 | 0.0874 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 2 | H10 | 72 | hr | 2543 | 2670 | 5761 | 0.4634 | 0.0420 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 3 | H10 | 72 | hr | 2543 | 2617 | 5760 | 0.4543 | 0.0245 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 1 | H09 | 72 | hr | 2543 | 2110 | 5734 | 0.3680 | -0.1473 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 2 | H09 | 72 | hr | 2543 | 2042 | 5761 | 0.3544 | -0.1699 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 3 | H09 | 72 | hr | 2543 | 2256 | 5760 | 0.3916 | -0.0967 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 1 | H08 | 72 | hr | 2543 | 2174 | 5734 | 0.3791 | -0.1253 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 2 | H08 | 72 | hr | 2543 | 2036 | 5761 | 0.3534 | -0.1719 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 3 | H08 | 72 | hr | 2543 | 2301 | 5760 | 0.3994 | -0.0814 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 1 | H07 | 72 | hr | 2543 | 1866 | 5734 | 0.3254 | -0.2321 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 2 | H07 | 72 | hr | 2543 | 1819 | 5761 | 0.3157 | -0.2474 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 3 | H07 | 72 | hr | 2543 | 2010 | 5760 | 0.3489 | -0.1809 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 1 | J06 | 72 | hr | 2543 | 4991 | 5258 | 0.9491 | 0.9027 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 2 | J06 | 72 | hr | 2543 | 4743 | 5438 | 0.8722 | 0.7654 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 3 | J06 | 72 | hr | 2543 | 5448 | 5557 | 0.9803 | 0.9651 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 1 | J05 | 72 | hr | 2543 | 4221 | 5258 | 0.8027 | 0.6215 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 2 | J05 | 72 | hr | 2543 | 4145 | 5438 | 0.7622 | 0.5612 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 3 | J05 | 72 | hr | 2543 | 4511 | 5557 | 0.8117 | 0.6622 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 1 | J04 | 72 | hr | 2543 | 3416 | 5258 | 0.6496 | 0.3251 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 2 | J04 | 72 | hr | 2543 | 2916 | 5438 | 0.5362 | 0.1328 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 3 | J04 | 72 | hr | 2543 | 3445 | 5557 | 0.6199 | 0.3087 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 1 | J03 | 72 | hr | 2543 | 1821 | 5258 | 0.3463 | -0.2730 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 2 | J03 | 72 | hr | 2543 | 1651 | 5438 | 0.3036 | -0.3258 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 3 | J03 | 72 | hr | 2543 | 1956 | 5557 | 0.3520 | -0.2078 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 1 | J02 | 72 | hr | 2543 | 1322 | 5258 | 0.2514 | -0.4644 |