LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Trametinib | 3.33 | uM | LJP5 | 3 | P20 | 72 | hr | 2543 | 4392 | 5760 | 0.7624 | 0.5890 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 1 | P19 | 72 | hr | 2543 | 4189 | 5734 | 0.7305 | 0.5302 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 2 | P19 | 72 | hr | 2543 | 4297 | 5761 | 0.7458 | 0.5598 |
| SK-BR-3 | Trametinib | 10 | uM | LJP5 | 3 | P19 | 72 | hr | 2543 | 4663 | 5760 | 0.8094 | 0.6718 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 1 | N06 | 72 | hr | 2543 | 1767 | 5258 | 0.3360 | -0.2936 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 2 | N06 | 72 | hr | 2543 | 1949 | 5438 | 0.3584 | -0.2156 |
| SK-BR-3 | Omipalisib | 0.04 | uM | LJP6 | 3 | N06 | 72 | hr | 2543 | 1988 | 5557 | 0.3577 | -0.1963 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 1 | N05 | 72 | hr | 2543 | 1706 | 5258 | 0.3244 | -0.3169 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 2 | N05 | 72 | hr | 2543 | 1631 | 5438 | 0.2999 | -0.3332 |
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 3 | N05 | 72 | hr | 2543 | 1716 | 5557 | 0.3088 | -0.2946 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 1 | N04 | 72 | hr | 2543 | 1524 | 5258 | 0.2898 | -0.3866 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 2 | N04 | 72 | hr | 2543 | 1501 | 5438 | 0.2760 | -0.3819 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 3 | N04 | 72 | hr | 2543 | 1478 | 5557 | 0.2660 | -0.3821 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 1 | N03 | 72 | hr | 2543 | 1273 | 5258 | 0.2421 | -0.4834 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 2 | N03 | 72 | hr | 2543 | 1209 | 5438 | 0.2223 | -0.4926 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 3 | N03 | 72 | hr | 2543 | 1387 | 5557 | 0.2496 | -0.4159 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 1 | N02 | 72 | hr | 2543 | 1065 | 5258 | 0.2025 | -0.5643 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 2 | N02 | 72 | hr | 2543 | 1016 | 5438 | 0.1868 | -0.5670 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 3 | N02 | 72 | hr | 2543 | 1027 | 5557 | 0.1848 | -0.5526 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 1 | N01 | 72 | hr | 2543 | 635 | 5258 | 0.1208 | -0.7340 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 2 | N01 | 72 | hr | 2543 | 734 | 5438 | 0.1350 | -0.6781 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 3 | N01 | 72 | hr | 2543 | 739 | 5557 | 0.1330 | -0.6658 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 1 | H06 | 72 | hr | 2543 | 5640 | 5734 | 0.9835 | 0.9719 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 2 | H06 | 72 | hr | 2543 | 5221 | 5761 | 0.9062 | 0.8398 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 3 | H06 | 72 | hr | 2543 | 5870 | 5760 | 1.0189 | 1.0321 |