LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 3 | E12 | 72 | hr | 2543 | 5726 | 5760 | 0.9940 | 0.9897 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 1 | E11 | 72 | hr | 2543 | 4613 | 5734 | 0.8044 | 0.6613 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 2 | E11 | 72 | hr | 2543 | 5025 | 5761 | 0.8722 | 0.7811 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 3 | E11 | 72 | hr | 2543 | 4481 | 5760 | 0.7778 | 0.6163 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 1 | E10 | 72 | hr | 2543 | 3408 | 5734 | 0.5943 | 0.2834 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 2 | E10 | 72 | hr | 2543 | 3607 | 5761 | 0.6261 | 0.3447 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 3 | E10 | 72 | hr | 2543 | 3252 | 5760 | 0.5645 | 0.2316 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 1 | E09 | 72 | hr | 2543 | 2546 | 5734 | 0.4440 | 0.0009 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 2 | E09 | 72 | hr | 2543 | 2511 | 5761 | 0.4358 | -0.0108 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 3 | E09 | 72 | hr | 2543 | 2394 | 5760 | 0.4156 | -0.0500 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 1 | E08 | 72 | hr | 2543 | 2182 | 5734 | 0.3805 | -0.1225 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 2 | E08 | 72 | hr | 2543 | 2423 | 5761 | 0.4206 | -0.0403 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 3 | E08 | 72 | hr | 2543 | 2255 | 5760 | 0.3914 | -0.0970 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 1 | E07 | 72 | hr | 2543 | 1647 | 5734 | 0.2872 | -0.3096 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 2 | E07 | 72 | hr | 2543 | 1446 | 5761 | 0.2510 | -0.3804 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 3 | E07 | 72 | hr | 2543 | 1498 | 5760 | 0.2600 | -0.3616 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 2543 | 5543 | 5258 | 1.0540 | 1.1030 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 2543 | 5246 | 5438 | 0.9647 | 0.9354 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 2543 | 5124 | 5557 | 0.9220 | 0.8611 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 1 | G11 | 72 | hr | 2543 | 5152 | 5258 | 0.9797 | 0.9612 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 2543 | 5152 | 5438 | 0.9474 | 0.9038 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 2543 | 4872 | 5557 | 0.8767 | 0.7797 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 1 | G10 | 72 | hr | 2543 | 2344 | 5258 | 0.4457 | -0.0750 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 2 | G10 | 72 | hr | 2543 | 2250 | 5438 | 0.4137 | -0.1058 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 3 | G10 | 72 | hr | 2543 | 2240 | 5557 | 0.4031 | -0.1066 |