LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 2 | D08 | 72 | hr | 2543 | 2041 | 5761 | 0.3543 | -0.1702 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 3 | D08 | 72 | hr | 2543 | 2076 | 5760 | 0.3604 | -0.1582 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 1 | D07 | 72 | hr | 2543 | 1964 | 5734 | 0.3425 | -0.1978 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 2 | D07 | 72 | hr | 2543 | 2049 | 5761 | 0.3556 | -0.1674 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 3 | D07 | 72 | hr | 2543 | 2181 | 5760 | 0.3786 | -0.1222 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 2543 | 5416 | 5734 | 0.9445 | 0.9049 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 2 | C18 | 72 | hr | 2543 | 5680 | 5761 | 0.9859 | 0.9760 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 2543 | 5868 | 5760 | 1.0186 | 1.0315 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 1 | C17 | 72 | hr | 2543 | 5673 | 5734 | 0.9893 | 0.9817 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 2 | C17 | 72 | hr | 2543 | 5604 | 5761 | 0.9727 | 0.9536 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 3 | C17 | 72 | hr | 2543 | 5891 | 5760 | 1.0226 | 1.0382 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 2543 | 5633 | 5734 | 0.9823 | 0.9698 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 2 | C16 | 72 | hr | 2543 | 5988 | 5761 | 1.0393 | 1.0665 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 2543 | 6223 | 5760 | 1.0802 | 1.1352 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 1 | C15 | 72 | hr | 2543 | 5826 | 5734 | 1.0160 | 1.0272 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 2 | C15 | 72 | hr | 2543 | 5858 | 5761 | 1.0168 | 1.0284 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 3 | C15 | 72 | hr | 2543 | 6113 | 5760 | 1.0611 | 1.1032 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 1 | C14 | 72 | hr | 2543 | 5380 | 5734 | 0.9382 | 0.8941 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 2 | C14 | 72 | hr | 2543 | 5876 | 5761 | 1.0199 | 1.0337 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 3 | C14 | 72 | hr | 2543 | 5944 | 5760 | 1.0318 | 1.0538 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 1 | C13 | 72 | hr | 2543 | 5119 | 5734 | 0.8927 | 0.8155 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 2 | C13 | 72 | hr | 2543 | 5469 | 5761 | 0.9492 | 0.9136 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 2543 | 4988 | 5760 | 0.8658 | 0.7701 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 2543 | 5897 | 5734 | 1.0283 | 1.0482 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 2 | D18 | 72 | hr | 2543 | 6163 | 5761 | 1.0697 | 1.1176 |