LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BX-912 | 3.33 | uM | LJP5 | 3 | L20 | 72 | hr | 2543 | 2354 | 5760 | 0.4086 | -0.0635 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 1 | L19 | 72 | hr | 2543 | 2162 | 5734 | 0.3770 | -0.1294 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 2 | L19 | 72 | hr | 2543 | 2163 | 5761 | 0.3754 | -0.1283 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 3 | L19 | 72 | hr | 2543 | 2137 | 5760 | 0.3710 | -0.1372 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 1 | M12 | 72 | hr | 2543 | 5908 | 5258 | 1.1234 | 1.2349 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 2 | M12 | 72 | hr | 2543 | 5750 | 5438 | 1.0573 | 1.1044 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 3 | M12 | 72 | hr | 2543 | 5796 | 5557 | 1.0429 | 1.0760 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 1 | M11 | 72 | hr | 2543 | 5575 | 5258 | 1.0601 | 1.1146 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 2 | M11 | 72 | hr | 2543 | 5389 | 5438 | 0.9910 | 0.9835 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 3 | M11 | 72 | hr | 2543 | 5514 | 5557 | 0.9922 | 0.9862 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 1 | M10 | 72 | hr | 2543 | 5524 | 5258 | 1.0504 | 1.0961 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 2 | M10 | 72 | hr | 2543 | 5517 | 5438 | 1.0145 | 1.0264 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 3 | M10 | 72 | hr | 2543 | 5607 | 5557 | 1.0089 | 1.0158 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 1 | M09 | 72 | hr | 2543 | 5311 | 5258 | 1.0099 | 1.0189 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 2 | M09 | 72 | hr | 2543 | 5639 | 5438 | 1.0369 | 1.0673 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 3 | M09 | 72 | hr | 2543 | 5585 | 5557 | 1.0050 | 1.0088 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 1 | M08 | 72 | hr | 2543 | 5477 | 5258 | 1.0415 | 1.0791 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 2 | M08 | 72 | hr | 2543 | 5495 | 5438 | 1.0105 | 1.0191 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 3 | M08 | 72 | hr | 2543 | 5221 | 5557 | 0.9395 | 0.8923 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 1 | M07 | 72 | hr | 2543 | 5427 | 5258 | 1.0320 | 1.0610 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 2 | M07 | 72 | hr | 2543 | 5093 | 5438 | 0.9365 | 0.8839 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 3 | M07 | 72 | hr | 2543 | 5273 | 5557 | 0.9488 | 0.9090 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 1 | F06 | 72 | hr | 2543 | 4756 | 5258 | 0.9044 | 0.8171 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 2 | F06 | 72 | hr | 2543 | 4548 | 5438 | 0.8363 | 0.6991 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 3 | F06 | 72 | hr | 2543 | 4652 | 5557 | 0.8371 | 0.7082 |