LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1694 11177 11099 1.0070 1.0051
MCF 10A Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1694 10995 11168 0.9845 0.9885
MCF 10A Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1694 9520 11220 0.8484 0.8830
MCF 10A Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1694 9996 11309 0.8839 0.9119
MCF 10A Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1694 10028 11121 0.9017 0.9252
MCF 10A Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1694 9709 11042 0.8793 0.9071
MCF 10A Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 1694 9999 11099 0.9009 0.9245
MCF 10A Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1694 9990 11168 0.8945 0.9197
MCF 10A Withaferin A
1.11
uM
LJP6
 1
G15
 72
hr
 1694 764 11220 0.0681 -0.2532
MCF 10A Withaferin A
1.11
uM
LJP6
 2
G15
 72
hr
 1694 1260 11309 0.1114 -0.1025
MCF 10A Withaferin A
1.11
uM
LJP6
 3
G15
 72
hr
 1694 1215 11121 0.1093 -0.1153
MCF 10A Withaferin A
1.11
uM
LJP5
 1
G15
 72
hr
 1694 1132 11042 0.1025 -0.1385
MCF 10A Withaferin A
1.11
uM
LJP5
 2
G15
 72
hr
 1694 1296 11099 0.1168 -0.0941
MCF 10A Withaferin A
1.11
uM
LJP5
 3
G15
 72
hr
 1694 1318 11168 0.1180 -0.0882
MCF 10A Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1694 401 11220 0.0357 -0.4104
MCF 10A Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1694 407 11309 0.0360 -0.4059
MCF 10A Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1694 408 11121 0.0367 -0.4081
MCF 10A Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1694 503 11042 0.0456 -0.3618
MCF 10A Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1694 500 11099 0.0450 -0.3624
MCF 10A Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1694 437 11168 0.0391 -0.3923
MCF 10A Withaferin A
10
uM
LJP6
 1
G13
 72
hr
 1694 231 11220 0.0206 -0.5184
MCF 10A Withaferin A
10
uM
LJP6
 2
G13
 72
hr
 1694 244 11309 0.0216 -0.5072
MCF 10A Withaferin A
10
uM
LJP6
 3
G13
 72
hr
 1694 248 11121 0.0223 -0.5073
MCF 10A Withaferin A
10
uM
LJP5
 1
G13
 72
hr
 1694 319 11042 0.0289 -0.4607
MCF 10A Withaferin A
10
uM
LJP5
 2
G13
 72
hr
 1694 266 11099 0.0240 -0.4948