LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 1389 553 5740 0.0963 -0.3623
MCF7 SNS-032
10
uM
LJP6
 1
H13
 72
hr
 1389 376 5147 0.0731 -0.4992
MCF7 SNS-032
10
uM
LJP6
 2
H13
 72
hr
 1389 452 5447 0.0830 -0.4342
MCF7 SNS-032
10
uM
LJP6
 3
H13
 72
hr
 1389 506 5740 0.0881 -0.3894
MCF7 Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 1389 4907 5147 0.9534 0.9501
MCF7 Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 1389 4573 5447 0.8394 0.8301
MCF7 Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 1389 4145 5740 0.7221 0.7059
MCF7 Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 1389 5180 5147 1.0064 1.0068
MCF7 Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 1389 5068 5447 0.9303 0.9280
MCF7 Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 1389 4241 5740 0.7388 0.7251
MCF7 Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 1389 4954 5147 0.9625 0.9599
MCF7 Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 1389 4643 5447 0.8523 0.8442
MCF7 Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 1389 5204 5740 0.9065 0.9064
MCF7 Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 1389 4845 5147 0.9413 0.9370
MCF7 Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1389 4254 5447 0.7809 0.7642
MCF7 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1389 4840 5740 0.8431 0.8401
MCF7 Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 1389 3547 5147 0.6891 0.6423
MCF7 Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 1389 3883 5447 0.7128 0.6844
MCF7 Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 1389 3847 5740 0.6702 0.6448
MCF7 Afatinib
10
uM
LJP6
 1
G19
 72
hr
 1389 624 5147 0.1212 -0.3452
MCF7 Afatinib
10
uM
LJP6
 2
G19
 72
hr
 1389 720 5447 0.1322 -0.2834
MCF7 Afatinib
10
uM
LJP6
 3
G19
 72
hr
 1389 938 5740 0.1634 -0.1745
MCF7 GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 1389 3645 5147 0.7082 0.6662
MCF7 GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 1389 3799 5447 0.6973 0.6658
MCF7 GSK1904529A
0.04
uM
LJP6
 3
H24
 72
hr
 1389 3501 5740 0.6099 0.5708