LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A LDN-193189
10
uM
LJP5
 2
G01
 72
hr
 1694 334 11099 0.0301 -0.4505
MCF 10A LDN-193189
10
uM
LJP5
 3
G01
 72
hr
 1694 357 11168 0.0320 -0.4358
MCF 10A PF431396
0.04
uM
LJP5
 1
E12
 72
hr
 1694 7328 11042 0.6636 0.7186
MCF 10A PF431396
0.04
uM
LJP5
 2
E12
 72
hr
 1694 7419 11099 0.6684 0.7239
MCF 10A PF431396
0.04
uM
LJP5
 3
E12
 72
hr
 1694 7260 11168 0.6501 0.7072
MCF 10A PF431396
0.12
uM
LJP5
 1
E11
 72
hr
 1694 5698 11042 0.5160 0.5660
MCF 10A PF431396
0.12
uM
LJP5
 2
E11
 72
hr
 1694 5806 11099 0.5231 0.5749
MCF 10A PF431396
0.12
uM
LJP5
 3
E11
 72
hr
 1694 5591 11168 0.5006 0.5509
MCF 10A PF431396
0.37
uM
LJP5
 1
E10
 72
hr
 1694 3667 11042 0.3321 0.3305
MCF 10A PF431396
0.37
uM
LJP5
 2
E10
 72
hr
 1694 3774 11099 0.3400 0.3436
MCF 10A PF431396
0.37
uM
LJP5
 3
E10
 72
hr
 1694 3551 11168 0.3180 0.3126
MCF 10A PF431396
1.11
uM
LJP5
 1
E09
 72
hr
 1694 2360 11042 0.2137 0.1304
MCF 10A PF431396
1.11
uM
LJP5
 2
E09
 72
hr
 1694 2225 11099 0.2005 0.1057
MCF 10A PF431396
1.11
uM
LJP5
 3
E09
 72
hr
 1694 2151 11168 0.1926 0.0917
MCF 10A PF431396
3.33
uM
LJP5
 1
E08
 72
hr
 1694 1953 11042 0.1769 0.0540
MCF 10A PF431396
3.33
uM
LJP5
 2
E08
 72
hr
 1694 1913 11099 0.1724 0.0458
MCF 10A PF431396
3.33
uM
LJP5
 3
E08
 72
hr
 1694 1774 11168 0.1588 0.0170
MCF 10A PF431396
10
uM
LJP5
 1
E07
 72
hr
 1694 701 11042 0.0635 -0.2784
MCF 10A PF431396
10
uM
LJP5
 2
E07
 72
hr
 1694 764 11099 0.0688 -0.2545
MCF 10A PF431396
10
uM
LJP5
 3
E07
 72
hr
 1694 677 11168 0.0606 -0.2862
MCF 10A Celastrol
0.04
uM
LJP6
 1
G12
 72
hr
 1694 12016 11220 1.0709 1.0508
MCF 10A Celastrol
0.04
uM
LJP6
 2
G12
 72
hr
 1694 12002 11309 1.0612 1.0439
MCF 10A Celastrol
0.04
uM
LJP6
 3
G12
 72
hr
 1694 11672 11121 1.0495 1.0359
MCF 10A Celastrol
0.12
uM
LJP6
 1
G11
 72
hr
 1694 12496 11220 1.1136 1.0805
MCF 10A Celastrol
0.12
uM
LJP6
 2
G11
 72
hr
 1694 12369 11309 1.0937 1.0665