LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 2 | O01 | 72 | hr | 1694 | 957 | 11309 | 0.0846 | -0.1883 |
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 3 | O01 | 72 | hr | 1694 | 626 | 11121 | 0.0563 | -0.3070 |
| MCF 10A | Geldanamycin | 10 | uM | LJP5 | 1 | O01 | 72 | hr | 1694 | 761 | 11042 | 0.0689 | -0.2562 |
| MCF 10A | Geldanamycin | 10 | uM | LJP5 | 2 | O01 | 72 | hr | 1694 | 1170 | 11099 | 0.1054 | -0.1276 |
| MCF 10A | Geldanamycin | 10 | uM | LJP5 | 3 | O01 | 72 | hr | 1694 | 844 | 11168 | 0.0756 | -0.2260 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 1 | N12 | 72 | hr | 1694 | 11648 | 11042 | 1.0548 | 1.0399 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 2 | N12 | 72 | hr | 1694 | 11121 | 11099 | 1.0019 | 1.0014 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 3 | N12 | 72 | hr | 1694 | 11380 | 11168 | 1.0190 | 1.0138 |
| MCF 10A | YM 201636 | 0.12 | uM | LJP5 | 1 | N11 | 72 | hr | 1694 | 11219 | 11042 | 1.0160 | 1.0118 |
| MCF 10A | YM 201636 | 0.12 | uM | LJP5 | 2 | N11 | 72 | hr | 1694 | 10622 | 11099 | 0.9570 | 0.9678 |
| MCF 10A | YM 201636 | 0.12 | uM | LJP5 | 3 | N11 | 72 | hr | 1694 | 11205 | 11168 | 1.0033 | 1.0024 |
| MCF 10A | YM 201636 | 0.37 | uM | LJP5 | 1 | N10 | 72 | hr | 1694 | 10232 | 11042 | 0.9266 | 0.9444 |
| MCF 10A | YM 201636 | 0.37 | uM | LJP5 | 2 | N10 | 72 | hr | 1694 | 9913 | 11099 | 0.8931 | 0.9183 |
| MCF 10A | YM 201636 | 0.37 | uM | LJP5 | 3 | N10 | 72 | hr | 1694 | 10586 | 11168 | 0.9479 | 0.9610 |
| MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 1 | N09 | 72 | hr | 1694 | 8854 | 11042 | 0.8018 | 0.8432 |
| MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 2 | N09 | 72 | hr | 1694 | 8687 | 11099 | 0.7827 | 0.8272 |
| MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 3 | N09 | 72 | hr | 1694 | 9101 | 11168 | 0.8149 | 0.8550 |
| MCF 10A | YM 201636 | 3.33 | uM | LJP5 | 1 | N08 | 72 | hr | 1694 | 8335 | 11042 | 0.7548 | 0.8024 |
| MCF 10A | YM 201636 | 3.33 | uM | LJP5 | 2 | N08 | 72 | hr | 1694 | 8146 | 11099 | 0.7339 | 0.7844 |
| MCF 10A | YM 201636 | 3.33 | uM | LJP5 | 3 | N08 | 72 | hr | 1694 | 8299 | 11168 | 0.7431 | 0.7932 |
| MCF 10A | YM 201636 | 10 | uM | LJP5 | 1 | N07 | 72 | hr | 1694 | 3755 | 11042 | 0.3401 | 0.3422 |
| MCF 10A | YM 201636 | 10 | uM | LJP5 | 2 | N07 | 72 | hr | 1694 | 3430 | 11099 | 0.3090 | 0.2971 |
| MCF 10A | YM 201636 | 10 | uM | LJP5 | 3 | N07 | 72 | hr | 1694 | 3223 | 11168 | 0.2886 | 0.2666 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1694 | 11322 | 11042 | 1.0253 | 1.0186 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 2 | M06 | 72 | hr | 1694 | 11415 | 11099 | 1.0284 | 1.0208 |