LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | PF562271 | 3.33 | uM | LJP6 | 1 | F14 | 72 | hr | 1694 | 2112 | 11220 | 0.1882 | 0.0842 |
| MCF 10A | PF562271 | 3.33 | uM | LJP6 | 2 | F14 | 72 | hr | 1694 | 2240 | 11309 | 0.1981 | 0.1073 |
| MCF 10A | PF562271 | 3.33 | uM | LJP6 | 3 | F14 | 72 | hr | 1694 | 2147 | 11121 | 0.1931 | 0.0912 |
| MCF 10A | PF562271 | 10 | uM | LJP6 | 1 | F13 | 72 | hr | 1694 | 454 | 11220 | 0.0405 | -0.3830 |
| MCF 10A | PF562271 | 10 | uM | LJP6 | 2 | F13 | 72 | hr | 1694 | 502 | 11309 | 0.0444 | -0.3586 |
| MCF 10A | PF562271 | 10 | uM | LJP6 | 3 | F13 | 72 | hr | 1694 | 526 | 11121 | 0.0473 | -0.3501 |
| MCF 10A | PHA-793887 | 0.04 | uM | LJP6 | 1 | E24 | 72 | hr | 1694 | 4029 | 11220 | 0.3591 | 0.3738 |
| MCF 10A | PHA-793887 | 0.04 | uM | LJP6 | 2 | E24 | 72 | hr | 1694 | 3895 | 11309 | 0.3444 | 0.3552 |
| MCF 10A | PHA-793887 | 0.04 | uM | LJP6 | 3 | E24 | 72 | hr | 1694 | 3475 | 11121 | 0.3125 | 0.3029 |
| MCF 10A | PHA-793887 | 0.12 | uM | LJP6 | 1 | E23 | 72 | hr | 1694 | 3462 | 11220 | 0.3085 | 0.2995 |
| MCF 10A | PHA-793887 | 0.12 | uM | LJP6 | 2 | E23 | 72 | hr | 1694 | 3507 | 11309 | 0.3101 | 0.3043 |
| MCF 10A | PHA-793887 | 0.12 | uM | LJP6 | 3 | E23 | 72 | hr | 1694 | 3184 | 11121 | 0.2863 | 0.2616 |
| MCF 10A | PHA-793887 | 0.37 | uM | LJP6 | 1 | E22 | 72 | hr | 1694 | 2880 | 11220 | 0.2567 | 0.2147 |
| MCF 10A | PHA-793887 | 0.37 | uM | LJP6 | 2 | E22 | 72 | hr | 1694 | 2800 | 11309 | 0.2476 | 0.2013 |
| MCF 10A | PHA-793887 | 0.37 | uM | LJP6 | 3 | E22 | 72 | hr | 1694 | 2453 | 11121 | 0.2206 | 0.1461 |
| MCF 10A | PHA-793887 | 1.11 | uM | LJP6 | 1 | E21 | 72 | hr | 1694 | 2345 | 11220 | 0.2090 | 0.1266 |
| MCF 10A | PHA-793887 | 1.11 | uM | LJP6 | 2 | E21 | 72 | hr | 1694 | 2134 | 11309 | 0.1887 | 0.0879 |
| MCF 10A | PHA-793887 | 1.11 | uM | LJP6 | 3 | E21 | 72 | hr | 1694 | 2277 | 11121 | 0.2048 | 0.1151 |
| MCF 10A | PHA-793887 | 3.33 | uM | LJP6 | 1 | E20 | 72 | hr | 1694 | 1602 | 11220 | 0.1428 | -0.0203 |
| MCF 10A | PHA-793887 | 3.33 | uM | LJP6 | 2 | E20 | 72 | hr | 1694 | 1705 | 11309 | 0.1508 | 0.0023 |
| MCF 10A | PHA-793887 | 3.33 | uM | LJP6 | 3 | E20 | 72 | hr | 1694 | 1433 | 11121 | 0.1289 | -0.0598 |
| MCF 10A | PHA-793887 | 10 | uM | LJP6 | 1 | E19 | 72 | hr | 1694 | 605 | 11220 | 0.0539 | -0.3145 |
| MCF 10A | PHA-793887 | 10 | uM | LJP6 | 2 | E19 | 72 | hr | 1694 | 547 | 11309 | 0.0484 | -0.3382 |
| MCF 10A | PHA-793887 | 10 | uM | LJP6 | 3 | E19 | 72 | hr | 1694 | 523 | 11121 | 0.0470 | -0.3514 |
| MCF 10A | QL-X-138 | 0.04 | uM | LJP6 | 1 | F24 | 72 | hr | 1694 | 12146 | 11220 | 1.0824 | 1.0589 |