LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Selumetinib
10
uM
LJP6
 3
M07
 72
hr
 1694 2842 11121 0.2556 0.2099
MCF 10A MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 1694 11589 11220 1.0328 1.0238
MCF 10A MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 1694 11759 11309 1.0398 1.0287
MCF 10A MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 1694 11338 11121 1.0195 1.0143
MCF 10A MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 1694 11358 11220 1.0122 1.0089
MCF 10A MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 1694 11651 11309 1.0302 1.0219
MCF 10A MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 1694 11079 11121 0.9962 0.9972
MCF 10A MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 1694 7318 11220 0.6522 0.7099
MCF 10A MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 1694 7694 11309 0.6803 0.7376
MCF 10A MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 1694 7148 11121 0.6427 0.6995
MCF 10A MK2206
1.11
uM
LJP6
 1
F03
 72
hr
 1694 10669 11220 0.9508 0.9634
MCF 10A MK2206
1.11
uM
LJP6
 2
F03
 72
hr
 1694 10892 11309 0.9631 0.9727
MCF 10A MK2206
1.11
uM
LJP6
 3
F03
 72
hr
 1694 10621 11121 0.9550 0.9664
MCF 10A MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 1694 9943 11220 0.8861 0.9133
MCF 10A MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 1694 10131 11309 0.8958 0.9212
MCF 10A MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 1694 10065 11121 0.9050 0.9278
MCF 10A MK2206
10
uM
LJP6
 1
F01
 72
hr
 1694 5449 11220 0.4856 0.5347
MCF 10A MK2206
10
uM
LJP6
 2
F01
 72
hr
 1694 5957 11309 0.5267 0.5826
MCF 10A MK2206
10
uM
LJP6
 3
F01
 72
hr
 1694 4933 11121 0.4436 0.4824
MCF 10A AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 1694 11183 11042 1.0127 1.0094
MCF 10A AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 1694 10970 11099 0.9883 0.9914
MCF 10A AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 1694 11484 11168 1.0283 1.0206
MCF 10A AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 1694 10967 11042 0.9932 0.9949
MCF 10A AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 1694 10401 11099 0.9371 0.9526
MCF 10A AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 1694 10990 11168 0.9840 0.9882