LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A KIN001-043
3.33
uM
LJP6
 1
C08
 72
hr
 1694 10128 11220 0.9026 0.9263
MCF 10A KIN001-043
3.33
uM
LJP6
 2
C08
 72
hr
 1694 9703 11309 0.8580 0.8912
MCF 10A KIN001-043
3.33
uM
LJP6
 3
C08
 72
hr
 1694 10090 11121 0.9073 0.9296
MCF 10A KIN001-043
10
uM
LJP6
 1
C07
 72
hr
 1694 5591 11220 0.4983 0.5492
MCF 10A KIN001-043
10
uM
LJP6
 2
C07
 72
hr
 1694 6056 11309 0.5355 0.5922
MCF 10A KIN001-043
10
uM
LJP6
 3
C07
 72
hr
 1694 4697 11121 0.4224 0.4559
MCF 10A Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 1694 11567 11220 1.0308 1.0224
MCF 10A Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 1694 11426 11309 1.0103 1.0075
MCF 10A Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 1694 11301 11121 1.0162 1.0119
MCF 10A Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 1694 11137 11220 0.9925 0.9945
MCF 10A Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 1694 10153 11309 0.8978 0.9228
MCF 10A Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 1694 10823 11121 0.9732 0.9801
MCF 10A Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 1694 10426 11220 0.9292 0.9468
MCF 10A Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 1694 9698 11309 0.8575 0.8908
MCF 10A Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 1694 9937 11121 0.8935 0.9188
MCF 10A Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 1694 8233 11220 0.7337 0.7854
MCF 10A Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 1694 7942 11309 0.7023 0.7578
MCF 10A Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 1694 7789 11121 0.7004 0.7541
MCF 10A Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 1694 6394 11220 0.5698 0.6273
MCF 10A Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 1694 5668 11309 0.5012 0.5541
MCF 10A Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 1694 5752 11121 0.5172 0.5687
MCF 10A Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 1694 2585 11220 0.2304 0.1675
MCF 10A Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 1694 2416 11309 0.2136 0.1383
MCF 10A Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 1694 2339 11121 0.2103 0.1261
MCF 10A Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1694 11167 11042 1.0113 1.0083