LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PD173074
10
uM
LJP6
 2
I07
 72
hr
 1694 6668 11309 0.5896 0.6491
MCF 10A PD173074
10
uM
LJP6
 3
I07
 72
hr
 1694 6623 11121 0.5955 0.6524
MCF 10A Crizotinib
0.04
uM
LJP5
 1
A24
 72
hr
 1694 10901 11042 0.9872 0.9905
MCF 10A Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 1694 10927 11099 0.9845 0.9885
MCF 10A Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 1694 10810 11168 0.9679 0.9762
MCF 10A Crizotinib
0.12
uM
LJP5
 1
A23
 72
hr
 1694 10498 11042 0.9507 0.9630
MCF 10A Crizotinib
0.12
uM
LJP5
 2
A23
 72
hr
 1694 10513 11099 0.9472 0.9604
MCF 10A Crizotinib
0.12
uM
LJP5
 3
A23
 72
hr
 1694 10636 11168 0.9523 0.9644
MCF 10A Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 1694 10034 11042 0.9087 0.9304
MCF 10A Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 1694 9918 11099 0.8936 0.9187
MCF 10A Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 1694 10017 11168 0.8969 0.9216
MCF 10A Crizotinib
1.11
uM
LJP5
 1
A21
 72
hr
 1694 9726 11042 0.8808 0.9083
MCF 10A Crizotinib
1.11
uM
LJP5
 2
A21
 72
hr
 1694 9742 11099 0.8777 0.9061
MCF 10A Crizotinib
1.11
uM
LJP5
 3
A21
 72
hr
 1694 10001 11168 0.8955 0.9205
MCF 10A Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 1694 9094 11042 0.8236 0.8615
MCF 10A Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 1694 8909 11099 0.8027 0.8443
MCF 10A Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 1694 9028 11168 0.8084 0.8496
MCF 10A Crizotinib
10
uM
LJP5
 1
A19
 72
hr
 1694 2091 11042 0.1894 0.0809
MCF 10A Crizotinib
10
uM
LJP5
 2
A19
 72
hr
 1694 2233 11099 0.2012 0.1072
MCF 10A Crizotinib
10
uM
LJP5
 3
A19
 72
hr
 1694 1985 11168 0.1777 0.0599
MCF 10A BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 1694 11096 11220 0.9889 0.9918
MCF 10A BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 1694 11260 11309 0.9956 0.9968
MCF 10A BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 1694 10906 11121 0.9807 0.9857
MCF 10A BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 1694 10692 11220 0.9529 0.9649
MCF 10A BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 1694 10851 11309 0.9595 0.9700