LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Dasatinib | 0.37 | uM | LJP5 | 3 | D04 | 72 | hr | 1694 | 3140 | 11168 | 0.2812 | 0.2545 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 1 | I03 | 72 | hr | 1694 | 2162 | 11220 | 0.1927 | 0.0935 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 2 | I03 | 72 | hr | 1694 | 2171 | 11309 | 0.1920 | 0.0948 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP6 | 3 | I03 | 72 | hr | 1694 | 1852 | 11121 | 0.1665 | 0.0333 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP5 | 1 | D03 | 72 | hr | 1694 | 2298 | 11042 | 0.2081 | 0.1193 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP5 | 2 | D03 | 72 | hr | 1694 | 2324 | 11099 | 0.2094 | 0.1236 |
| MCF 10A | Dasatinib | 1.11 | uM | LJP5 | 3 | D03 | 72 | hr | 1694 | 2645 | 11168 | 0.2368 | 0.1779 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP6 | 1 | I02 | 72 | hr | 1694 | 1521 | 11220 | 0.1356 | -0.0388 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP6 | 2 | I02 | 72 | hr | 1694 | 1371 | 11309 | 0.1212 | -0.0744 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP6 | 3 | I02 | 72 | hr | 1694 | 1091 | 11121 | 0.0981 | -0.1497 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP5 | 1 | D02 | 72 | hr | 1694 | 1716 | 11042 | 0.1554 | 0.0047 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP5 | 2 | D02 | 72 | hr | 1694 | 2079 | 11099 | 0.1873 | 0.0784 |
| MCF 10A | Dasatinib | 3.33 | uM | LJP5 | 3 | D02 | 72 | hr | 1694 | 1763 | 11168 | 0.1579 | 0.0147 |
| MCF 10A | Dasatinib | 10 | uM | LJP6 | 1 | I01 | 72 | hr | 1694 | 1093 | 11220 | 0.0974 | -0.1485 |
| MCF 10A | Dasatinib | 10 | uM | LJP6 | 2 | I01 | 72 | hr | 1694 | 946 | 11309 | 0.0836 | -0.1917 |
| MCF 10A | Dasatinib | 10 | uM | LJP6 | 3 | I01 | 72 | hr | 1694 | 576 | 11121 | 0.0518 | -0.3280 |
| MCF 10A | Dasatinib | 10 | uM | LJP5 | 1 | D01 | 72 | hr | 1694 | 1355 | 11042 | 0.1227 | -0.0793 |
| MCF 10A | Dasatinib | 10 | uM | LJP5 | 2 | D01 | 72 | hr | 1694 | 1180 | 11099 | 0.1063 | -0.1249 |
| MCF 10A | Dasatinib | 10 | uM | LJP5 | 3 | D01 | 72 | hr | 1694 | 1219 | 11168 | 0.1092 | -0.1140 |
| MCF 10A | Tozasertib | 0.04 | uM | LJP5 | 1 | B18 | 72 | hr | 1694 | 6186 | 11042 | 0.5602 | 0.6143 |
| MCF 10A | Tozasertib | 0.04 | uM | LJP5 | 2 | B18 | 72 | hr | 1694 | 6210 | 11099 | 0.5595 | 0.6145 |
| MCF 10A | Tozasertib | 0.04 | uM | LJP5 | 3 | B18 | 72 | hr | 1694 | 6652 | 11168 | 0.5956 | 0.6532 |
| MCF 10A | Tozasertib | 0.12 | uM | LJP5 | 1 | B17 | 72 | hr | 1694 | 1978 | 11042 | 0.1791 | 0.0589 |
| MCF 10A | Tozasertib | 0.12 | uM | LJP5 | 2 | B17 | 72 | hr | 1694 | 1973 | 11099 | 0.1778 | 0.0578 |
| MCF 10A | Tozasertib | 0.12 | uM | LJP5 | 3 | B17 | 72 | hr | 1694 | 2052 | 11168 | 0.1837 | 0.0730 |