LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 1694 | 2548 | 11220 | 0.2271 | 0.1614 |
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 2 | A07 | 72 | hr | 1694 | 2272 | 11309 | 0.2009 | 0.1131 |
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 3 | A07 | 72 | hr | 1694 | 2302 | 11121 | 0.2070 | 0.1195 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 1694 | 12387 | 11220 | 1.1039 | 1.0738 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 2 | B12 | 72 | hr | 1694 | 11751 | 11309 | 1.0391 | 1.0282 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 1694 | 12052 | 11121 | 1.0837 | 1.0601 |
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 1 | B11 | 72 | hr | 1694 | 12219 | 11220 | 1.0889 | 1.0635 |
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 2 | B11 | 72 | hr | 1694 | 11307 | 11309 | 0.9998 | 0.9999 |
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 3 | B11 | 72 | hr | 1694 | 11948 | 11121 | 1.0744 | 1.0535 |
| MCF 10A | Sorafenib | 0.37 | uM | LJP6 | 1 | B10 | 72 | hr | 1694 | 11562 | 11220 | 1.0304 | 1.0221 |
| MCF 10A | Sorafenib | 0.37 | uM | LJP6 | 2 | B10 | 72 | hr | 1694 | 11297 | 11309 | 0.9989 | 0.9992 |
| MCF 10A | Sorafenib | 0.37 | uM | LJP6 | 3 | B10 | 72 | hr | 1694 | 11462 | 11121 | 1.0306 | 1.0224 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 1694 | 11278 | 11220 | 1.0051 | 1.0037 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 1694 | 10653 | 11309 | 0.9420 | 0.9568 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 1694 | 11115 | 11121 | 0.9995 | 0.9996 |
| MCF 10A | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 1694 | 10704 | 11220 | 0.9539 | 0.9657 |
| MCF 10A | Sorafenib | 3.33 | uM | LJP6 | 2 | B08 | 72 | hr | 1694 | 10026 | 11309 | 0.8865 | 0.9140 |
| MCF 10A | Sorafenib | 3.33 | uM | LJP6 | 3 | B08 | 72 | hr | 1694 | 10788 | 11121 | 0.9700 | 0.9777 |
| MCF 10A | Sorafenib | 10 | uM | LJP6 | 1 | B07 | 72 | hr | 1694 | 6772 | 11220 | 0.6035 | 0.6620 |
| MCF 10A | Sorafenib | 10 | uM | LJP6 | 2 | B07 | 72 | hr | 1694 | 6341 | 11309 | 0.5607 | 0.6191 |
| MCF 10A | Sorafenib | 10 | uM | LJP6 | 3 | B07 | 72 | hr | 1694 | 6567 | 11121 | 0.5905 | 0.6472 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 1 | I12 | 72 | hr | 1694 | 11683 | 11042 | 1.0580 | 1.0421 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 2 | I12 | 72 | hr | 1694 | 11387 | 11099 | 1.0259 | 1.0189 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 3 | I12 | 72 | hr | 1694 | 11377 | 11168 | 1.0187 | 1.0137 |
| MCF 10A | CP466722 | 0.12 | uM | LJP5 | 1 | I11 | 72 | hr | 1694 | 11197 | 11042 | 1.0140 | 1.0103 |