LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 1389 2237 5772 0.3875 0.2610
MCF7 PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 1389 2548 6038 0.4220 0.3313
MCF7 PD0325901
10
uM
LJP6
 1
E01
 72
hr
 1389 1221 5147 0.2372 -0.0660
MCF7 PD0325901
10
uM
LJP6
 2
E01
 72
hr
 1389 1599 5447 0.2935 0.0740
MCF7 PD0325901
10
uM
LJP6
 3
E01
 72
hr
 1389 1564 5740 0.2725 0.0597
MCF7 PD0325901
10
uM
LJP5
 1
C01
 72
hr
 1389 1322 5772 0.2290 -0.0238
MCF7 PD0325901
10
uM
LJP5
 3
C01
 72
hr
 1389 1447 6038 0.2396 0.0195
MCF7 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 1389 3546 5147 0.6889 0.6421
MCF7 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 1389 3532 5447 0.6483 0.6054
MCF7 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 1389 3305 5740 0.5757 0.5272
MCF7 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 1389 3508 5772 0.6077 0.5696
MCF7 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 1389 3846 6038 0.6369 0.6167
MCF7 Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 1389 1944 5147 0.3777 0.1947
MCF7 Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 1389 1801 5447 0.3306 0.1408
MCF7 Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 1389 1732 5740 0.3017 0.1138
MCF7 Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 1389 1782 5772 0.3087 0.1289
MCF7 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 1389 2064 6038 0.3418 0.2054
MCF7 Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 1389 1394 5147 0.2708 0.0019
MCF7 Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 1389 1351 5447 0.2480 -0.0140
MCF7 Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 1389 1458 5740 0.2540 0.0239
MCF7 Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 1389 1489 5772 0.2580 0.0344
MCF7 Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 1389 1529 6038 0.2532 0.0463
MCF7 Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 1389 1505 5147 0.2924 0.0433
MCF7 Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 1389 1688 5447 0.3098 0.1039
MCF7 Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 1389 1540 5740 0.2683 0.0517