LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Ruxolitinib
10
uM
LJP5
 1
O13
 72
hr
 765 2187 3140 0.6964 0.6746
Hs 578T Ruxolitinib
10
uM
LJP5
 2
O13
 72
hr
 765 2090 3151 0.6632 0.6357
Hs 578T Ruxolitinib
10
uM
LJP5
 3
O13
 72
hr
 765 2176 3152 0.6903 0.6681
Hs 578T Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 765 2930 3140 0.9330 0.9331
Hs 578T Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 765 3030 3151 0.9614 0.9618
Hs 578T Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 765 2982 3152 0.9459 0.9463
Hs 578T Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 765 2809 3140 0.8945 0.8935
Hs 578T Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 765 2739 3151 0.8691 0.8672
Hs 578T Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 765 2706 3152 0.8584 0.8560
Hs 578T Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 765 2506 3140 0.7980 0.7903
Hs 578T Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 765 2432 3151 0.7717 0.7616
Hs 578T Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 765 2584 3152 0.8197 0.8145
Hs 578T Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 765 2318 3140 0.7381 0.7231
Hs 578T Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 765 2105 3151 0.6679 0.6414
Hs 578T Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 765 2112 3152 0.6700 0.6439
Hs 578T Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 765 1860 3140 0.5923 0.5466
Hs 578T Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 765 1809 3151 0.5740 0.5240
Hs 578T Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 765 1881 3152 0.5967 0.5533
Hs 578T Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 765 758 3140 0.2414 -0.0045
Hs 578T Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 765 760 3151 0.2411 -0.0032
Hs 578T Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 765 744 3152 0.2360 -0.0136
Hs 578T Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 765 3060 3140 0.9744 0.9747
Hs 578T Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 765 3314 3151 1.0515 1.0498
Hs 578T Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 765 3238 3152 1.0271 1.0264
Hs 578T Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 765 3118 3140 0.9929 0.9930