LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 765 1770 3143 0.5630 0.5089
Hs 578T Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 765 1851 3095 0.5979 0.5498
Hs 578T Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 765 1797 3066 0.5861 0.5317
Hs 578T Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 765 1583 3143 0.5035 0.4285
Hs 578T Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 765 1626 3095 0.5253 0.4533
Hs 578T Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 765 1453 3066 0.4739 0.3775
Hs 578T Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 765 1450 3143 0.4612 0.3683
Hs 578T Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 765 1580 3095 0.5104 0.4328
Hs 578T Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 765 1505 3066 0.4909 0.4019
Hs 578T Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 765 1406 3143 0.4472 0.3478
Hs 578T Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 765 1390 3095 0.4490 0.3446
Hs 578T Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 765 1336 3066 0.4358 0.3210
Hs 578T PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 765 2757 3143 0.8770 0.8753
Hs 578T PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 765 2788 3095 0.9006 0.8988
Hs 578T PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 765 2762 3066 0.9009 0.8984
Hs 578T PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 765 2550 3143 0.8111 0.8049
Hs 578T PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 765 2587 3095 0.8357 0.8297
Hs 578T PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 765 2369 3066 0.7727 0.7583
Hs 578T PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 765 2345 3143 0.7459 0.7322
Hs 578T PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 765 2239 3095 0.7233 0.7032
Hs 578T PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 765 2170 3066 0.7078 0.6830
Hs 578T PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 765 2074 3143 0.6597 0.6309
Hs 578T PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 765 1947 3095 0.6290 0.5892
Hs 578T PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 765 1888 3066 0.6158 0.5700
Hs 578T PF562271
3.33
uM
LJP6
 1
F14
 72
hr
 765 1544 3143 0.4911 0.4111