LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 765 1017 3151 0.3227 0.1496
Hs 578T Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 765 1013 3152 0.3213 0.1473
Hs 578T Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 765 902 3140 0.2872 0.0842
Hs 578T Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 765 995 3151 0.3157 0.1373
Hs 578T Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 765 939 3152 0.2979 0.1055
Hs 578T Barasertib
10
uM
LJP5
 1
D07
 72
hr
 765 880 3140 0.2802 0.0711
Hs 578T Barasertib
10
uM
LJP5
 2
D07
 72
hr
 765 864 3151 0.2741 0.0614
Hs 578T Barasertib
10
uM
LJP5
 3
D07
 72
hr
 765 846 3152 0.2684 0.0505
Hs 578T Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 765 3336 3140 1.0623 1.0602
Hs 578T Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 765 3309 3151 1.0499 1.0483
Hs 578T Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 765 3303 3152 1.0478 1.0462
Hs 578T Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 765 3299 3140 1.0505 1.0490
Hs 578T Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 765 3214 3151 1.0198 1.0193
Hs 578T Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 765 3260 3152 1.0341 1.0331
Hs 578T Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 765 3344 3140 1.0648 1.0626
Hs 578T Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 765 3322 3151 1.0541 1.0522
Hs 578T Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 765 3195 3152 1.0135 1.0132
Hs 578T Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 765 3294 3140 1.0489 1.0474
Hs 578T Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 765 3279 3151 1.0404 1.0392
Hs 578T Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 765 3299 3152 1.0465 1.0450
Hs 578T Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 765 3000 3140 0.9553 0.9556
Hs 578T Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 765 2986 3151 0.9474 0.9478
Hs 578T Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 765 3057 3152 0.9697 0.9701
Hs 578T Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 765 1872 3140 0.5961 0.5515
Hs 578T Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 765 1953 3151 0.6197 0.5823