LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 765 2851 3143 0.9069 0.9064
Hs 578T MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 765 2748 3095 0.8877 0.8853
Hs 578T MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 765 2705 3066 0.8823 0.8787
Hs 578T MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 765 2585 3143 0.8223 0.8170
Hs 578T MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 765 2330 3095 0.7527 0.7372
Hs 578T MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 765 2407 3066 0.7851 0.7724
Hs 578T MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 765 1743 3143 0.5544 0.4976
Hs 578T MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 765 1781 3095 0.5753 0.5205
Hs 578T MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 765 1676 3066 0.5466 0.4793
Hs 578T MK2206
1.11
uM
LJP6
 1
F03
 72
hr
 765 2138 3143 0.6801 0.6554
Hs 578T MK2206
1.11
uM
LJP6
 2
F03
 72
hr
 765 2091 3095 0.6755 0.6464
Hs 578T MK2206
1.11
uM
LJP6
 3
F03
 72
hr
 765 2119 3066 0.6911 0.6631
Hs 578T MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 765 1954 3143 0.6215 0.5839
Hs 578T MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 765 2030 3095 0.6558 0.6224
Hs 578T MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 765 2058 3066 0.6712 0.6390
Hs 578T MK2206
10
uM
LJP6
 1
F01
 72
hr
 765 2332 3143 0.7418 0.7275
Hs 578T MK2206
10
uM
LJP6
 2
F01
 72
hr
 765 2404 3095 0.7766 0.7643
Hs 578T MK2206
10
uM
LJP6
 3
F01
 72
hr
 765 2236 3066 0.7293 0.7083
Hs 578T AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 765 2834 3140 0.9025 0.9017
Hs 578T AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 765 2802 3151 0.8891 0.8881
Hs 578T AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 765 2827 3152 0.8968 0.8961
Hs 578T AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 765 2638 3140 0.8400 0.8360
Hs 578T AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 765 2800 3151 0.8884 0.8875
Hs 578T AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 765 2777 3152 0.8809 0.8796
Hs 578T AZD-6482
0.37
uM
LJP5
 1
I04
 72
hr
 765 2659 3140 0.8467 0.8432