LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 1334 2814 4051 0.6946 0.5931
BT-20 Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 1334 2165 4117 0.5258 0.3467
BT-20 Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1334 4119 3955 1.0413 1.0523
BT-20 Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1334 4089 3899 1.0487 1.0624
BT-20 Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1334 4355 3921 1.1106 1.1396
BT-20 Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 1334 4465 3955 1.1287 1.1606
BT-20 Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 1334 3960 3899 1.0156 1.0201
BT-20 Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 1334 3874 3921 0.9879 0.9844
BT-20 Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 1334 4050 3955 1.0238 1.0303
BT-20 Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 1334 3746 3899 0.9607 0.9489
BT-20 Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 1334 3699 3921 0.9433 0.9263
BT-20 Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 1334 4074 3955 1.0299 1.0379
BT-20 Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 1334 3737 3899 0.9584 0.9458
BT-20 Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 1334 3734 3921 0.9522 0.9380
BT-20 Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 1334 4008 3955 1.0132 1.0168
BT-20 Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 1334 3685 3899 0.9451 0.9283
BT-20 Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 1334 3413 3921 0.8704 0.8292
BT-20 Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 1334 3801 3955 0.9609 0.9497
BT-20 Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 1334 3469 3899 0.8897 0.8544
BT-20 Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 1334 3452 3921 0.8803 0.8426
BT-20 Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 1334 4066 3930 1.0344 1.0439
BT-20 Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 1334 4536 4051 1.1197 1.1463
BT-20 Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 1334 3703 4117 0.8993 0.8736
BT-20 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 1334 4177 3930 1.0626 1.0795
BT-20 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 1334 4290 4051 1.0590 1.0728