LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 1389 3763 5447 0.6907 0.6578
MCF7 Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 1389 3561 5740 0.6203 0.5839
MCF7 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 1389 2286 5147 0.4441 0.3017
MCF7 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 1389 2175 5447 0.3992 0.2554
MCF7 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 1389 2574 5740 0.4484 0.3517
MCF7 Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 1389 1671 5147 0.3247 0.1027
MCF7 Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 1389 1916 5447 0.3517 0.1772
MCF7 Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 1389 1847 5740 0.3218 0.1493
MCF7 Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 1389 1449 5147 0.2815 0.0226
MCF7 Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 1389 1651 5447 0.3031 0.0916
MCF7 Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 1389 1445 5740 0.2517 0.0195
MCF7 Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 1389 1695 5147 0.3293 0.1111
MCF7 Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 1389 1709 5447 0.3137 0.1109
MCF7 Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 1389 1598 5740 0.2784 0.0708
MCF7 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1389 4210 5772 0.7293 0.7153
MCF7 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 1389 4569 6038 0.7566 0.7535
MCF7 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 1389 4417 5772 0.7652 0.7558
MCF7 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 1389 4807 6038 0.7961 0.7960
MCF7 Sigma A6730
0.37
uM
LJP5
 1
B22
 72
hr
 1389 4575 5772 0.7926 0.7861
MCF7 Sigma A6730
0.37
uM
LJP5
 3
B22
 72
hr
 1389 4976 6038 0.8241 0.8255
MCF7 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 1389 3376 5772 0.5848 0.5405
MCF7 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 1389 3531 6038 0.5848 0.5528
MCF7 Sigma A6730
3.33
uM
LJP5
 1
B20
 72
hr
 1389 3159 5772 0.5473 0.4915
MCF7 Sigma A6730
3.33
uM
LJP5
 3
B20
 72
hr
 1389 3751 6038 0.6212 0.5977
MCF7 Sigma A6730
10
uM
LJP5
 1
B19
 72
hr
 1389 1500 5772 0.2599 0.0381