LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 1 | M13 | 72 | hr | 2543 | 2174 | 5734 | 0.3791 | -0.1253 |
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 2 | M13 | 72 | hr | 2543 | 2346 | 5761 | 0.4072 | -0.0662 |
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 3 | M13 | 72 | hr | 2543 | 2252 | 5760 | 0.3909 | -0.0980 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 1 | N06 | 72 | hr | 2543 | 5169 | 5734 | 0.9014 | 0.8306 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 2 | N06 | 72 | hr | 2543 | 5106 | 5761 | 0.8862 | 0.8054 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 3 | N06 | 72 | hr | 2543 | 5624 | 5760 | 0.9762 | 0.9596 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 2543 | 4829 | 5734 | 0.8421 | 0.7274 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 2 | N05 | 72 | hr | 2543 | 5129 | 5761 | 0.8902 | 0.8123 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 3 | N05 | 72 | hr | 2543 | 5246 | 5760 | 0.9106 | 0.8474 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 1 | N04 | 72 | hr | 2543 | 4428 | 5734 | 0.7722 | 0.6043 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 2 | N04 | 72 | hr | 2543 | 4703 | 5761 | 0.8163 | 0.6838 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 3 | N04 | 72 | hr | 2543 | 5028 | 5760 | 0.8728 | 0.7821 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 2543 | 4392 | 5734 | 0.7659 | 0.5932 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 2543 | 4111 | 5761 | 0.7135 | 0.5023 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 2543 | 4499 | 5760 | 0.7810 | 0.6218 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 2543 | 3151 | 5734 | 0.5495 | 0.2004 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 2 | N02 | 72 | hr | 2543 | 3340 | 5761 | 0.5797 | 0.2598 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 2543 | 3520 | 5760 | 0.6110 | 0.3172 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 1 | N01 | 72 | hr | 2543 | 1949 | 5734 | 0.3399 | -0.2031 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 2 | N01 | 72 | hr | 2543 | 1806 | 5761 | 0.3135 | -0.2519 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 3 | N01 | 72 | hr | 2543 | 2061 | 5760 | 0.3578 | -0.1633 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 1 | K24 | 72 | hr | 2543 | 3136 | 5734 | 0.5469 | 0.1955 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 2 | K24 | 72 | hr | 2543 | 3165 | 5761 | 0.5493 | 0.2036 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 3 | K24 | 72 | hr | 2543 | 3518 | 5760 | 0.6107 | 0.3165 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 2543 | 2537 | 5734 | 0.4424 | -0.0022 |