LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | TGX221 | 10 | uM | LJP5 | 2 | H19 | 72 | hr | 2543 | 5738 | 5761 | 0.9959 | 0.9931 |
| SK-BR-3 | TGX221 | 10 | uM | LJP5 | 3 | H19 | 72 | hr | 2543 | 5541 | 5760 | 0.9618 | 0.9351 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP6 | 1 | C06 | 72 | hr | 2543 | 5049 | 5258 | 0.9601 | 0.9238 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP6 | 2 | C06 | 72 | hr | 2543 | 5313 | 5438 | 0.9770 | 0.9580 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP6 | 3 | C06 | 72 | hr | 2543 | 4983 | 5557 | 0.8967 | 0.8156 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP5 | 1 | E06 | 72 | hr | 2543 | 6009 | 5734 | 1.0479 | 1.0813 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP5 | 2 | E06 | 72 | hr | 2543 | 5866 | 5761 | 1.0182 | 1.0307 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP5 | 3 | E06 | 72 | hr | 2543 | 5845 | 5760 | 1.0146 | 1.0247 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 1 | C05 | 72 | hr | 2543 | 4334 | 5258 | 0.8241 | 0.6629 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 2 | C05 | 72 | hr | 2543 | 4005 | 5438 | 0.7365 | 0.5131 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 3 | C05 | 72 | hr | 2543 | 4643 | 5557 | 0.8355 | 0.7053 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 1 | E05 | 72 | hr | 2543 | 5536 | 5734 | 0.9654 | 0.9408 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 2 | E05 | 72 | hr | 2543 | 5560 | 5761 | 0.9650 | 0.9406 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 3 | E05 | 72 | hr | 2543 | 5701 | 5760 | 0.9896 | 0.9824 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 1 | C04 | 72 | hr | 2543 | 3433 | 5258 | 0.6528 | 0.3313 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 2 | C04 | 72 | hr | 2543 | 3465 | 5438 | 0.6372 | 0.3258 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 3 | C04 | 72 | hr | 2543 | 3517 | 5557 | 0.6329 | 0.3330 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 1 | E04 | 72 | hr | 2543 | 4668 | 5734 | 0.8140 | 0.6782 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 2 | E04 | 72 | hr | 2543 | 4901 | 5761 | 0.8507 | 0.7437 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 3 | E04 | 72 | hr | 2543 | 4995 | 5760 | 0.8671 | 0.7722 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 1 | C03 | 72 | hr | 2543 | 2086 | 5258 | 0.3967 | -0.1724 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 2 | C03 | 72 | hr | 2543 | 2150 | 5438 | 0.3954 | -0.1421 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 3 | C03 | 72 | hr | 2543 | 2194 | 5557 | 0.3948 | -0.1229 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP5 | 1 | E03 | 72 | hr | 2543 | 2537 | 5734 | 0.4424 | -0.0022 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP5 | 2 | E03 | 72 | hr | 2543 | 2689 | 5761 | 0.4667 | 0.0483 |