LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 1235 2076 4356 0.4766 0.3304
MCF7 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1235 1709 4326 0.3950 0.1966
MCF7 Withaferin A
1.11
uM
LJP6
 1
G15
 72
hr
 1235 1279 3974 0.3218 0.0208
MCF7 Withaferin A
1.11
uM
LJP6
 2
G15
 72
hr
 1235 1414 4070 0.3474 0.0817
MCF7 Withaferin A
1.11
uM
LJP6
 3
G15
 72
hr
 1235 1320 4126 0.3199 0.0388
MCF7 Withaferin A
1.11
uM
LJP5
 1
G15
 72
hr
 1235 1587 4119 0.3853 0.1551
MCF7 Withaferin A
1.11
uM
LJP5
 2
G15
 72
hr
 1235 1549 4356 0.3556 0.1325
MCF7 Withaferin A
1.11
uM
LJP5
 3
G15
 72
hr
 1235 1553 4326 0.3590 0.1349
MCF7 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1235 956 3974 0.2406 -0.1411
MCF7 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1235 1078 4070 0.2648 -0.0762
MCF7 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1235 1119 4126 0.2712 -0.0553
MCF7 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1235 1097 4119 0.2663 -0.0661
MCF7 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1235 1021 4356 0.2344 -0.0995
MCF7 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1235 987 4326 0.2281 -0.1167
MCF7 Withaferin A
10
uM
LJP6
 1
G13
 72
hr
 1235 1051 3974 0.2645 -0.0914
MCF7 Withaferin A
10
uM
LJP6
 2
G13
 72
hr
 1235 1060 4070 0.2604 -0.0852
MCF7 Withaferin A
10
uM
LJP6
 3
G13
 72
hr
 1235 987 4126 0.2392 -0.1210
MCF7 Withaferin A
10
uM
LJP5
 1
G13
 72
hr
 1235 956 4119 0.2321 -0.1372
MCF7 Withaferin A
10
uM
LJP5
 2
G13
 72
hr
 1235 1102 4356 0.2530 -0.0609
MCF7 Withaferin A
10
uM
LJP5
 3
G13
 72
hr
 1235 1275 4326 0.2947 0.0176
MCF7
LJP6
 1
A03
 72
hr
 1235 3718 3974 0.9356 0.9225
MCF7
LJP6
 1
A04
 72
hr
 1235 3468 3974 0.8726 0.8447
MCF7
LJP6
 1
A05
 72
hr
 1235 3863 3974 0.9720 0.9666
MCF7
LJP6
 1
A06
 72
hr
 1235 2454 3974 0.6175 0.5025
MCF7
LJP6
 1
B03
 72
hr
 1235 3725 3974 0.9373 0.9246