LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Dasatinib | 1.11 | uM | LJP5 | 3 | D03 | 72 | hr | 1235 | 1076 | 4326 | 0.2487 | -0.0735 |
| MCF7 | Dasatinib | 3.33 | uM | LJP6 | 1 | I02 | 72 | hr | 1235 | 971 | 3974 | 0.2443 | -0.1331 |
| MCF7 | Dasatinib | 3.33 | uM | LJP6 | 2 | I02 | 72 | hr | 1235 | 926 | 4070 | 0.2275 | -0.1543 |
| MCF7 | Dasatinib | 3.33 | uM | LJP6 | 3 | I02 | 72 | hr | 1235 | 851 | 4126 | 0.2062 | -0.1928 |
| MCF7 | Dasatinib | 3.33 | uM | LJP5 | 1 | D02 | 72 | hr | 1235 | 954 | 4119 | 0.2316 | -0.1382 |
| MCF7 | Dasatinib | 3.33 | uM | LJP5 | 2 | D02 | 72 | hr | 1235 | 1041 | 4356 | 0.2390 | -0.0899 |
| MCF7 | Dasatinib | 3.33 | uM | LJP5 | 3 | D02 | 72 | hr | 1235 | 923 | 4326 | 0.2133 | -0.1489 |
| MCF7 | Dasatinib | 10 | uM | LJP6 | 1 | I01 | 72 | hr | 1235 | 767 | 3974 | 0.1930 | -0.2463 |
| MCF7 | Dasatinib | 10 | uM | LJP6 | 2 | I01 | 72 | hr | 1235 | 802 | 4070 | 0.1970 | -0.2221 |
| MCF7 | Dasatinib | 10 | uM | LJP6 | 3 | I01 | 72 | hr | 1235 | 790 | 4126 | 0.1915 | -0.2266 |
| MCF7 | Dasatinib | 10 | uM | LJP5 | 1 | D01 | 72 | hr | 1235 | 837 | 4119 | 0.2032 | -0.2008 |
| MCF7 | Dasatinib | 10 | uM | LJP5 | 2 | D01 | 72 | hr | 1235 | 955 | 4356 | 0.2192 | -0.1320 |
| MCF7 | Dasatinib | 10 | uM | LJP5 | 3 | D01 | 72 | hr | 1235 | 963 | 4326 | 0.2226 | -0.1287 |
| MCF7 | Tozasertib | 0.04 | uM | LJP5 | 1 | B18 | 72 | hr | 1235 | 1456 | 4119 | 0.3535 | 0.0992 |
| MCF7 | Tozasertib | 0.04 | uM | LJP5 | 2 | B18 | 72 | hr | 1235 | 1503 | 4356 | 0.3450 | 0.1139 |
| MCF7 | Tozasertib | 0.04 | uM | LJP5 | 3 | B18 | 72 | hr | 1235 | 1361 | 4326 | 0.3146 | 0.0550 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 1 | B17 | 72 | hr | 1235 | 1405 | 4119 | 0.3411 | 0.0769 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 2 | B17 | 72 | hr | 1235 | 1329 | 4356 | 0.3051 | 0.0410 |
| MCF7 | Tozasertib | 0.12 | uM | LJP5 | 3 | B17 | 72 | hr | 1235 | 1415 | 4326 | 0.3271 | 0.0780 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 1 | B16 | 72 | hr | 1235 | 1509 | 4119 | 0.3663 | 0.1220 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 2 | B16 | 72 | hr | 1235 | 1502 | 4356 | 0.3448 | 0.1135 |
| MCF7 | Tozasertib | 0.37 | uM | LJP5 | 3 | B16 | 72 | hr | 1235 | 1439 | 4326 | 0.3326 | 0.0880 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 1 | B15 | 72 | hr | 1235 | 1364 | 4119 | 0.3311 | 0.0587 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 2 | B15 | 72 | hr | 1235 | 1392 | 4356 | 0.3195 | 0.0679 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 3 | B15 | 72 | hr | 1235 | 1348 | 4326 | 0.3116 | 0.0494 |