High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 547 | 120 | | 5210 | 7031 | 116.5 | 33.51 | 67.29 | 88.49 | 82 | 90 | 96 | 102 | 109 | 116 | 126 | 140 | 161 | 0.1074 | 755 | 0.962 | 86.27 | 33.84 | 2 | 0.0478 | 249 | 0.0029 | 20.97 | 6.262 | 0.2723 | 14702.5 | 2030000 | 306000000 | 50600000000 | 0.4062 | 0.2387 | 0.0018 | 0.0000 | 0.0032 | 0.0000 | 0.0093 | 0.0009 | 0.0370 | 0.0017 | 0.1025 | 0.0273 | 0.1787 | 0.0577 | 0.1630 | 0.0624 | 0.1798 | 0.0955 | 0.3247 | 0.7545 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0044 | 0.0004 | 0.0154 | 0.0008 | 0.0427 | 0.0160 | 0.0740 | 0.0248 | 0.0717 | 0.0220 | 0.1040 | 0.0419 | 0.6847 | 0.8941 | 0.0019 | 0.0042 | 0.0049 | 0.0166 | 0.0165 | 0.0374 | 0.0525 | 0.0832 | 0.1380 | 0.1933 | 0.1672 | 0.2121 | 0.1263 | 0.0894 | 0.1545 | 0.1538 | 0.3382 | 0.2100 | 0.0039 | 0.0048 | 0.0101 | 0.0400 | 0.0761 | 0.1094 | 0.1104 | 0.1359 | 0.5094 | 12 | 15 | 20 | 26 | 33 | 43 | 64 | 100 | 163 | 0.0295 | 19.01 | 4.722 | 0.5549 | 12357.0 | 4090000 | 1840000000 | 978000000000 | 0.7256 | 0.0616 | 0.0176 | 0.0062 | 0.0821 | 0.0241 | 0.1437 | 0.0469 | 0.1935 | 0.0841 | 0.1686 | 0.1496 | 0.1569 | 0.1695 | 0.0997 | 0.1447 | 0.0982 | 0.1371 | 0.0396 | 0.2378 | 0.0025 | 0.0024 | 0.0050 | 0.0041 | 0.0103 | 0.0111 | 0.0227 | 0.0199 | 0.0900 | 0.0827 | 0.1399 | 0.1253 | 0.0929 | 0.0918 | 0.1312 | 0.1236 | 0.5056 | 0.5392 | 0.0011 | 0.0020 | 0.0092 | 0.0033 | 0.0075 | 0.0139 | 0.0316 | 0.0463 | 0.1086 | 0.1026 | 0.1580 | 0.1794 | 0.1080 | 0.1112 | 0.1356 | 0.1456 | 0.4406 | 0.3958 | 0.0034 | 0.0034 | 0.0112 | 0.0244 | 0.0937 | 0.1541 | 0.0941 | 0.1332 | 0.4824 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 933 | 123 | | 15895 | 25256 | 160.6 | 49.99 | 222.36 | 201.78 | 108 | 123 | 135 | 145 | 155 | 167 | 180 | 197 | 224 | 0.0522 | 1319 | 1.013 | 68.60 | 26.63 | 1 | 0.0118 | 188 | 0.0011 | 38.56 | 7.182 | 0.2007 | 28277.2 | 5410000 | 1120000000 | 250000000000 | 0.4469 | 0.2019 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0004 | 0.0316 | 0.0036 | 0.1026 | 0.0245 | 0.1744 | 0.0573 | 0.1683 | 0.0626 | 0.1924 | 0.0950 | 0.3207 | 0.7567 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0020 | 0.0001 | 0.0095 | 0.0013 | 0.0356 | 0.0107 | 0.0680 | 0.0249 | 0.0660 | 0.0239 | 0.0986 | 0.0414 | 0.7192 | 0.8976 | 0.0038 | 0.0039 | 0.0105 | 0.0143 | 0.0212 | 0.0306 | 0.0646 | 0.0971 | 0.1280 | 0.1519 | 0.1664 | 0.1956 | 0.1271 | 0.1167 | 0.1414 | 0.1402 | 0.3371 | 0.2497 | 0.0010 | 0.0033 | 0.0088 | 0.0321 | 0.0763 | 0.1269 | 0.1097 | 0.1304 | 0.5115 | 26 | 46 | 75 | 111 | 161 | 221 | 294 | 379 | 507 | 0.0037 | 85.09 | 7.177 | 0.2606 | 90156.2 | 49000000 | 32300000000 | 24700000000000 | 0.5277 | 0.1518 | 0.0405 | 0.0017 | 0.1859 | 0.0114 | 0.2913 | 0.0812 | 0.1595 | 0.1431 | 0.1289 | 0.2051 | 0.0931 | 0.1986 | 0.0540 | 0.1320 | 0.0300 | 0.1078 | 0.0167 | 0.1190 | 0.0003 | 0.0003 | 0.0017 | 0.0005 | 0.0033 | 0.0024 | 0.0137 | 0.0100 | 0.0734 | 0.0561 | 0.1231 | 0.1010 | 0.0947 | 0.0796 | 0.1369 | 0.1199 | 0.5529 | 0.6302 | 0.0009 | 0.0011 | 0.0033 | 0.0060 | 0.0084 | 0.0108 | 0.0290 | 0.0412 | 0.1013 | 0.1114 | 0.1586 | 0.1680 | 0.1119 | 0.1173 | 0.1427 | 0.1435 | 0.4438 | 0.4007 | 0.0005 | 0.0008 | 0.0048 | 0.0220 | 0.0840 | 0.1483 | 0.1014 | 0.1428 | 0.4955 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 923 | 124 | | 725 | 2122 | 76.0 | 19.18 | 87.85 | 150.35 | 55 | 62 | 66 | 70 | 74 | 78 | 82 | 89 | 98 | 0.1555 | 330 | 1.062 | 83.67 | 27.73 | 1 | 0.3007 | 218 | 0.0059 | 12.27 | 5.382 | 0.3021 | 6143.7 | 529049 | 48700000 | 4800000000 | 0.4598 | 0.1774 | 0.0021 | 0.0000 | 0.0105 | 0.0000 | 0.0316 | 0.0062 | 0.0547 | 0.0170 | 0.1116 | 0.0602 | 0.1495 | 0.0802 | 0.1558 | 0.0725 | 0.1811 | 0.1065 | 0.3032 | 0.6574 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0100 | 0.0014 | 0.0067 | 0.0029 | 0.0585 | 0.0432 | 0.1137 | 0.0748 | 0.0870 | 0.0489 | 0.1421 | 0.0691 | 0.5803 | 0.7597 | 0.0081 | 0.0213 | 0.0488 | 0.0000 | 0.0407 | 0.0638 | 0.0894 | 0.1489 | 0.2602 | 0.2340 | 0.1057 | 0.2340 | 0.1545 | 0.0638 | 0.1463 | 0.0851 | 0.1463 | 0.1489 | 0.0000 | 0.0030 | 0.0302 | 0.0604 | 0.1329 | 0.1813 | 0.1390 | 0.1601 | 0.2931 | 14 | 17 | 20 | 25 | 38 | 53 | 73 | 106 | 191 | 0.0472 | 42.92 | 4.329 | 0.5495 | 30310.8 | 21700000 | 20800000000 | 23000000000000 | 0.5356 | 0.1304 | 0.0400 | 0.0000 | 0.1778 | 0.0200 | 0.1689 | 0.0798 | 0.2267 | 0.1098 | 0.1289 | 0.1377 | 0.1333 | 0.1896 | 0.0978 | 0.1337 | 0.0178 | 0.1018 | 0.0089 | 0.2275 | 0.0015 | 0.0000 | 0.0122 | 0.0000 | 0.0198 | 0.0141 | 0.0517 | 0.0387 | 0.0836 | 0.0810 | 0.1049 | 0.1244 | 0.1094 | 0.0845 | 0.1261 | 0.1315 | 0.4909 | 0.5258 | 0.0000 | 0.0028 | 0.0139 | 0.0057 | 0.0254 | 0.0256 | 0.0647 | 0.0427 | 0.1062 | 0.1225 | 0.1201 | 0.1595 | 0.1178 | 0.0798 | 0.1293 | 0.1681 | 0.4226 | 0.3932 | 0.0019 | 0.0130 | 0.0093 | 0.0484 | 0.1043 | 0.1229 | 0.0987 | 0.1378 | 0.4637 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 421 | 124 | | 5496 | 10543 | 841.5 | 127.28 | 116.18 | 190.68 | 650 | 752 | 803 | 837 | 864 | 891 | 918 | 946 | 983 | 0.0719 | 758 | 0.901 | 57.38 | 16.12 | 1 | 0.0260 | 143 | 0.0008 | 45.33 | 7.373 | 0.1837 | 724381.0 | 635000000 | 565000000000 | 510000000000000 | 0.4046 | 0.2403 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0000 | 0.0037 | 0.0006 | 0.0217 | 0.0126 | 0.0354 | 0.0196 | 0.0394 | 0.0116 | 0.0630 | 0.0199 | 0.8361 | 0.9356 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0019 | 0.0006 | 0.0126 | 0.0126 | 0.0229 | 0.0196 | 0.0169 | 0.0116 | 0.0272 | 0.0199 | 0.9185 | 0.9356 | 0.0145 | 0.0000 | 0.0364 | 0.0000 | 0.0545 | 0.0000 | 0.1200 | 0.0000 | 0.1200 | 0.0000 | 0.1418 | 0.0000 | 0.1455 | 0.0000 | 0.1091 | 0.0000 | 0.2582 | 0.0000 | 0.0016 | 0.0038 | 0.0047 | 0.0144 | 0.0357 | 0.0510 | 0.0620 | 0.0780 | 0.7489 | 11 | 14 | 18 | 24 | 31 | 47 | 83 | 165 | 375 | 0.1122 | 20.14 | 4.053 | 0.6479 | 49852.9 | 32900000 | 26200000000 | 23500000000000 | 0.4577 | 0.2035 | 0.0423 | 0.0022 | 0.1482 | 0.0186 | 0.2052 | 0.1010 | 0.1580 | 0.1256 | 0.1612 | 0.1330 | 0.1075 | 0.1627 | 0.0749 | 0.1085 | 0.0619 | 0.1226 | 0.0407 | 0.2259 | 0.0007 | 0.0006 | 0.0007 | 0.0012 | 0.0071 | 0.0066 | 0.0172 | 0.0124 | 0.0487 | 0.0469 | 0.0774 | 0.0650 | 0.0551 | 0.0478 | 0.0804 | 0.0728 | 0.7127 | 0.7468 | 0.0000 | 0.0005 | 0.0004 | 0.0014 | 0.0030 | 0.0038 | 0.0179 | 0.0141 | 0.0640 | 0.0756 | 0.0989 | 0.1136 | 0.0648 | 0.0700 | 0.0942 | 0.1103 | 0.6567 | 0.6108 | 0.0000 | 0.0027 | 0.0027 | 0.0170 | 0.0572 | 0.0877 | 0.0634 | 0.0912 | 0.6781 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1218 | 127 | | 498 | 20452 | 136.6 | 11.03 | 9.21 | 3.44 | 125 | 129 | 132 | 134 | 137 | 139 | 142 | 145 | 150 | 0.0417 | 853 | 1.250 | 19.42 | 8.06 | 3 | 0.1104 | 55 | 0.0920 | 0.84 | 2.707 | 0.6980 | 18782.2 | 2600000 | 362000000 | 50600000000 | 0.4730 | 0.1733 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0103 | 0.0080 | 0.0103 | 0.0080 | 0.0514 | 0.0502 | 0.1337 | 0.1285 | 0.0638 | 0.0582 | 0.1008 | 0.0683 | 0.6276 | 0.6787 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0103 | 0.0080 | 0.0103 | 0.0080 | 0.0513 | 0.0502 | 0.1335 | 0.1285 | 0.0637 | 0.0582 | 0.0842 | 0.0683 | 0.6448 | 0.6787 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0080 | 0.0080 | 0.0319 | 0.0956 | 0.1873 | 0.1594 | 0.1912 | 0.1753 | 0.1434 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 14 | 0.3292 | 0.40 | 0.993 | 0.6993 | 96.6 | 1114.47 | 13902.1 | 185508 | 0.4877 | 0.1649 | 0.0427 | 0.0010 | 0.1299 | 0.0068 | 0.2175 | 0.0218 | 0.2344 | 0.0618 | 0.1940 | 0.1341 | 0.1196 | 0.2265 | 0.0482 | 0.2611 | 0.0121 | 0.2035 | 0.0016 | 0.0835 | 0.0015 | 0.0001 | 0.0101 | 0.0006 | 0.0312 | 0.0040 | 0.0680 | 0.0142 | 0.1176 | 0.0364 | 0.1753 | 0.0828 | 0.2208 | 0.1592 | 0.2235 | 0.3027 | 0.1521 | 0.4001 | 0.0590 | 0.1703 | 0.1271 | 0.2470 | 0.1772 | 0.2322 | 0.1954 | 0.1620 | 0.1825 | 0.0961 | 0.1334 | 0.0570 | 0.0783 | 0.0237 | 0.0376 | 0.0074 | 0.0095 | 0.0043 | 0.0081 | 0.0349 | 0.0676 | 0.1210 | 0.1670 | 0.1995 | 0.1880 | 0.1467 | 0.0671 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 128 | | 4381 | 3891 | 142.2 | 45.53 | 116.54 | 68.03 | 93 | 105 | 115 | 124 | 134 | 144 | 156 | 174 | 206 | 0.1773 | 690 | 1.154 | 92.96 | 30.48 | 1 | 0.0539 | 236 | 0.0014 | 45.81 | 6.878 | 0.1869 | 22305.5 | 3870000 | 744000000 | 158000000000 | 0.4152 | 0.2335 | 0.0000 | 0.0000 | 0.0045 | 0.0003 | 0.0186 | 0.0022 | 0.0626 | 0.0091 | 0.1392 | 0.0365 | 0.1946 | 0.0890 | 0.1642 | 0.0862 | 0.1655 | 0.1307 | 0.2508 | 0.6460 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0038 | 0.0010 | 0.0190 | 0.0034 | 0.0514 | 0.0191 | 0.0936 | 0.0528 | 0.0787 | 0.0396 | 0.1148 | 0.0671 | 0.6372 | 0.8169 | 0.0021 | 0.0099 | 0.0063 | 0.0079 | 0.0264 | 0.0258 | 0.0738 | 0.0813 | 0.1276 | 0.1488 | 0.1762 | 0.1925 | 0.1171 | 0.1310 | 0.1403 | 0.1587 | 0.3302 | 0.2440 | 0.0016 | 0.0054 | 0.0136 | 0.0490 | 0.1017 | 0.1447 | 0.1181 | 0.1371 | 0.4287 | 38 | 55 | 71 | 88 | 106 | 126 | 145 | 172 | 209 | 0.0023 | 29.24 | 6.422 | 0.2512 | 18208.7 | 3510000 | 804000000 | 216000000000 | 0.4985 | 0.1471 | 0.0212 | 0.0005 | 0.0945 | 0.0070 | 0.1741 | 0.0289 | 0.1656 | 0.0690 | 0.1975 | 0.1573 | 0.1592 | 0.1669 | 0.0902 | 0.1493 | 0.0637 | 0.1728 | 0.0340 | 0.2483 | 0.0018 | 0.0000 | 0.0041 | 0.0011 | 0.0091 | 0.0040 | 0.0279 | 0.0190 | 0.0741 | 0.0623 | 0.1189 | 0.0845 | 0.1006 | 0.0758 | 0.1161 | 0.1217 | 0.5473 | 0.6316 | 0.0048 | 0.0023 | 0.0088 | 0.0137 | 0.0201 | 0.0286 | 0.0530 | 0.0766 | 0.1349 | 0.1646 | 0.1743 | 0.1737 | 0.1245 | 0.1234 | 0.1414 | 0.1349 | 0.3382 | 0.2823 | 0.0006 | 0.0069 | 0.0103 | 0.0322 | 0.0925 | 0.1516 | 0.1040 | 0.1338 | 0.4681 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1069 | 128 | | 2783 | 11256 | 51.7 | 18.54 | 103.66 | 116.84 | 30 | 35 | 40 | 45 | 50 | 54 | 60 | 67 | 78 | 0.0861 | 969 | 0.603 | 152.75 | 27.51 | 6 | 0.1347 | 375 | 0.0052 | 9.08 | 5.547 | 0.3491 | 3018.8 | 195743 | 13900000 | 1050000000 | 0.4330 | 0.1802 | 0.0026 | 0.0005 | 0.0071 | 0.0000 | 0.0556 | 0.0035 | 0.1412 | 0.0262 | 0.1571 | 0.0657 | 0.1986 | 0.1226 | 0.1297 | 0.1409 | 0.1262 | 0.1557 | 0.1818 | 0.4849 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0017 | 0.0228 | 0.0132 | 0.0565 | 0.0405 | 0.1146 | 0.0653 | 0.0880 | 0.0690 | 0.1222 | 0.0860 | 0.5932 | 0.7243 | 0.0071 | 0.0025 | 0.0085 | 0.0354 | 0.0297 | 0.0303 | 0.0621 | 0.0581 | 0.1285 | 0.1465 | 0.1370 | 0.1641 | 0.1314 | 0.1237 | 0.1427 | 0.1717 | 0.3531 | 0.2677 | 0.0008 | 0.0000 | 0.0110 | 0.0432 | 0.0856 | 0.1540 | 0.1163 | 0.1406 | 0.4485 | 13 | 17 | 24 | 38 | 58 | 83 | 121 | 176 | 261 | 0.0237 | 15.67 | 5.256 | 0.4584 | 24394.3 | 8520000 | 3730000000 | 1900000000000 | 0.5135 | 0.1676 | 0.0460 | 0.0031 | 0.1957 | 0.0140 | 0.2492 | 0.0815 | 0.1672 | 0.1444 | 0.1530 | 0.1870 | 0.0962 | 0.1917 | 0.0552 | 0.1269 | 0.0268 | 0.1211 | 0.0109 | 0.1304 | 0.0004 | 0.0007 | 0.0020 | 0.0011 | 0.0080 | 0.0037 | 0.0214 | 0.0182 | 0.0764 | 0.0588 | 0.1256 | 0.1088 | 0.0857 | 0.0785 | 0.1129 | 0.1069 | 0.5677 | 0.6232 | 0.0021 | 0.0004 | 0.0030 | 0.0071 | 0.0118 | 0.0139 | 0.0300 | 0.0363 | 0.0919 | 0.0879 | 0.1475 | 0.1584 | 0.1001 | 0.0993 | 0.1186 | 0.1217 | 0.4948 | 0.4751 | 0.0005 | 0.0031 | 0.0065 | 0.0265 | 0.0749 | 0.1471 | 0.0884 | 0.1191 | 0.5339 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 623 | 128 | | 5953 | 11599 | 530.3 | 117.08 | 264.39 | 415.53 | 392 | 428 | 458 | 485 | 513 | 546 | 584 | 630 | 696 | 0.0813 | 943 | 0.967 | 130.08 | 35.78 | 1 | 0.0519 | 309 | 0.0004 | 120.83 | 7.914 | 0.1104 | 294936.0 | 172000000 | 105000000000 | 66500000000000 | 0.4302 | 0.2128 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0059 | 0.0004 | 0.0185 | 0.0013 | 0.0765 | 0.0215 | 0.1506 | 0.0396 | 0.1458 | 0.0420 | 0.1956 | 0.0637 | 0.4064 | 0.8314 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0076 | 0.0003 | 0.0384 | 0.0137 | 0.0657 | 0.0215 | 0.0657 | 0.0178 | 0.0966 | 0.0280 | 0.7218 | 0.9187 | 0.0044 | 0.0061 | 0.0000 | 0.0214 | 0.0142 | 0.0428 | 0.0567 | 0.1284 | 0.1258 | 0.1743 | 0.1709 | 0.2110 | 0.1116 | 0.1376 | 0.1515 | 0.1407 | 0.3649 | 0.1376 | 0.0015 | 0.0015 | 0.0083 | 0.0326 | 0.0701 | 0.1227 | 0.0848 | 0.1148 | 0.5638 | 9 | 12 | 15 | 20 | 32 | 87 | 235 | 532 | 918 | 0.0999 | 84.61 | 5.018 | 0.5316 | 242548.0 | 294000000 | 414000000000 | 650000000000000 | 0.4380 | 0.2212 | 0.0713 | 0.0000 | 0.2240 | 0.0143 | 0.2261 | 0.1554 | 0.1344 | 0.1964 | 0.1303 | 0.1954 | 0.0876 | 0.1573 | 0.0448 | 0.0925 | 0.0407 | 0.0944 | 0.0407 | 0.0944 | 0.0006 | 0.0000 | 0.0003 | 0.0013 | 0.0014 | 0.0020 | 0.0089 | 0.0075 | 0.0371 | 0.0362 | 0.0674 | 0.0619 | 0.0438 | 0.0415 | 0.0726 | 0.0714 | 0.7680 | 0.7782 | 0.0006 | 0.0000 | 0.0000 | 0.0007 | 0.0013 | 0.0014 | 0.0055 | 0.0051 | 0.0375 | 0.0471 | 0.0789 | 0.0792 | 0.0465 | 0.0567 | 0.0818 | 0.0857 | 0.7478 | 0.7240 | 0.0003 | 0.0030 | 0.0021 | 0.0087 | 0.0382 | 0.0659 | 0.0454 | 0.0728 | 0.7636 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 95 | 131 | | 989 | 1640 | 89.4 | 13.84 | 29.47 | 62.84 | 71 | 77 | 82 | 85 | 89 | 93 | 96 | 101 | 107 | 0.2116 | 347 | 0.177 | 169.76 | 32.53 | 2 | 0.8817 | 872 | 0.0651 | 1.08 | 3.063 | 0.6829 | 8181.5 | 766522 | 73500000 | 7210000000 | 0.3997 | 0.2450 | 0.0013 | 0.0000 | 0.0025 | 0.0000 | 0.0063 | 0.0000 | 0.0304 | 0.0061 | 0.0608 | 0.0348 | 0.0989 | 0.0583 | 0.1343 | 0.0409 | 0.1926 | 0.0502 | 0.4728 | 0.8096 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0022 | 0.0000 | 0.0169 | 0.0051 | 0.0371 | 0.0293 | 0.0573 | 0.0526 | 0.0629 | 0.0303 | 0.0843 | 0.0415 | 0.7371 | 0.8413 | 0.0594 | 0.0000 | 0.1089 | 0.3333 | 0.1188 | 0.2500 | 0.1485 | 0.2500 | 0.1485 | 0.0833 | 0.1782 | 0.0833 | 0.0594 | 0.0000 | 0.0792 | 0.0000 | 0.0990 | 0.0000 | 0.0019 | 0.0077 | 0.0232 | 0.0522 | 0.0754 | 0.1006 | 0.1528 | 0.2147 | 0.3714 | 8 | 10 | 12 | 13 | 15 | 17 | 20 | 26 | 43 | 0.3370 | 1.57 | 1.900 | 0.7940 | 4815.1 | 2160000 | 1340000000 | 961000000000 | 0.6590 | 0.0663 | 0.0476 | 0.0571 | 0.1429 | 0.0571 | 0.1905 | 0.0813 | 0.2434 | 0.1099 | 0.2487 | 0.1429 | 0.0794 | 0.1868 | 0.0476 | 0.1890 | 0.0000 | 0.1341 | 0.0000 | 0.0418 | 0.0128 | 0.0413 | 0.0434 | 0.0366 | 0.0561 | 0.0461 | 0.0918 | 0.0636 | 0.1429 | 0.0986 | 0.1709 | 0.1574 | 0.1301 | 0.1558 | 0.1071 | 0.1558 | 0.2449 | 0.2448 | 0.0246 | 0.0057 | 0.0148 | 0.0230 | 0.0296 | 0.0345 | 0.0788 | 0.0575 | 0.1478 | 0.1609 | 0.1773 | 0.2126 | 0.1281 | 0.1149 | 0.1232 | 0.1437 | 0.2759 | 0.2471 | 0.0223 | 0.0335 | 0.0520 | 0.0632 | 0.1561 | 0.1710 | 0.1227 | 0.1190 | 0.2602 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 284 | 132 | | 3587 | 822 | 127.8 | 29.04 | 269.41 | 172.52 | 95 | 103 | 110 | 116 | 124 | 131 | 139 | 150 | 166 | 0.4538 | 373 | 0.730 | 52.80 | 16.97 | 1 | 0.0435 | 156 | 0.0026 | 19.75 | 6.264 | 0.2480 | 17172.9 | 2430000 | 364000000 | 57600000000 | 0.4499 | 0.2003 | 0.0013 | 0.0000 | 0.0039 | 0.0000 | 0.0057 | 0.0006 | 0.0284 | 0.0024 | 0.0900 | 0.0181 | 0.1429 | 0.0404 | 0.1608 | 0.0440 | 0.2172 | 0.0871 | 0.3497 | 0.8073 | 0.0007 | 0.0000 | 0.0031 | 0.0000 | 0.0021 | 0.0000 | 0.0106 | 0.0011 | 0.0398 | 0.0118 | 0.0621 | 0.0230 | 0.0648 | 0.0149 | 0.1204 | 0.0342 | 0.6964 | 0.9150 | 0.0048 | 0.0197 | 0.0207 | 0.0542 | 0.0287 | 0.0690 | 0.0813 | 0.1232 | 0.1643 | 0.1675 | 0.1978 | 0.1773 | 0.1372 | 0.1330 | 0.1547 | 0.1182 | 0.2105 | 0.1379 | 0.0025 | 0.0044 | 0.0176 | 0.0478 | 0.0806 | 0.1233 | 0.1296 | 0.1517 | 0.4424 | 69 | 114 | 153 | 190 | 229 | 286 | 352 | 427 | 520 | 0.0018 | 138.36 | 6.442 | 0.1434 | 102307.0 | 47200000 | 24500000000 | 13800000000000 | 0.3578 | 0.2281 | 0.0612 | 0.0059 | 0.2245 | 0.0413 | 0.3197 | 0.1150 | 0.1905 | 0.1475 | 0.1020 | 0.2448 | 0.0748 | 0.2035 | 0.0136 | 0.1091 | 0.0136 | 0.0973 | 0.0000 | 0.0354 | 0.0023 | 0.0018 | 0.0093 | 0.0161 | 0.0395 | 0.0233 | 0.0302 | 0.0376 | 0.1674 | 0.1485 | 0.2256 | 0.2093 | 0.1605 | 0.1503 | 0.1581 | 0.1807 | 0.2070 | 0.2326 | 0.0000 | 0.0045 | 0.0071 | 0.0227 | 0.0247 | 0.0455 | 0.0813 | 0.0818 | 0.2226 | 0.2682 | 0.2438 | 0.2182 | 0.1696 | 0.1591 | 0.1060 | 0.0682 | 0.1449 | 0.1318 | 0.0029 | 0.0086 | 0.0173 | 0.0490 | 0.1844 | 0.2478 | 0.1729 | 0.1499 | 0.1671 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 508 | 133 | | 5112 | 15953 | 596.9 | 122.93 | 209.99 | 332.25 | 447 | 490 | 521 | 552 | 585 | 617 | 653 | 698 | 767 | 0.0564 | 899 | 0.855 | 86.15 | 24.76 | 1 | 0.0428 | 219 | 0.0004 | 156.57 | 7.925 | 0.1053 | 371349.0 | 241000000 | 162000000000 | 113000000000000 | 0.4423 | 0.2051 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0024 | 0.0000 | 0.0187 | 0.0008 | 0.0672 | 0.0192 | 0.1466 | 0.0410 | 0.1398 | 0.0373 | 0.1694 | 0.0551 | 0.4551 | 0.8466 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0089 | 0.0004 | 0.0325 | 0.0132 | 0.0678 | 0.0246 | 0.0610 | 0.0151 | 0.0909 | 0.0305 | 0.7386 | 0.9162 | 0.0023 | 0.0043 | 0.0103 | 0.0043 | 0.0195 | 0.0468 | 0.0736 | 0.1319 | 0.1310 | 0.1872 | 0.2080 | 0.2468 | 0.1023 | 0.0936 | 0.1264 | 0.1106 | 0.3264 | 0.1745 | 0.0008 | 0.0025 | 0.0105 | 0.0257 | 0.0758 | 0.1281 | 0.1049 | 0.1184 | 0.5333 | 8 | 10 | 12 | 14 | 20 | 73 | 208 | 417 | 696 | 0.1770 | 37.47 | 4.561 | 0.5961 | 154477.0 | 156000000 | 189000000000 | 260000000000000 | 0.5567 | 0.1171 | 0.0435 | 0.0017 | 0.1317 | 0.0133 | 0.1719 | 0.0920 | 0.1462 | 0.1123 | 0.1551 | 0.1516 | 0.1272 | 0.1707 | 0.1071 | 0.1244 | 0.0737 | 0.1291 | 0.0435 | 0.2049 | 0.0000 | 0.0003 | 0.0002 | 0.0000 | 0.0013 | 0.0010 | 0.0089 | 0.0045 | 0.0312 | 0.0322 | 0.0618 | 0.0501 | 0.0532 | 0.0353 | 0.0709 | 0.0694 | 0.7724 | 0.8070 | 0.0005 | 0.0002 | 0.0000 | 0.0007 | 0.0023 | 0.0015 | 0.0087 | 0.0100 | 0.0449 | 0.0500 | 0.0795 | 0.0826 | 0.0525 | 0.0585 | 0.0887 | 0.0933 | 0.7230 | 0.7032 | 0.0008 | 0.0015 | 0.0023 | 0.0088 | 0.0390 | 0.0736 | 0.0524 | 0.0793 | 0.7423 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1275 | 136 | | 348 | 1761 | 24.9 | 4.56 | 12.04 | 4.73 | 19 | 21 | 22 | 24 | 25 | 26 | 27 | 29 | 31 | 0.1550 | 273 | 0.753 | 89.14 | 19.31 | 1 | 0.6466 | 225 | 0.0917 | 1.19 | 2.649 | 0.6279 | 641.9 | 17045.4 | 465908 | 13100000 | 0.3990 | 0.2249 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0283 | 0.0000 | 0.0850 | 0.0208 | 0.1377 | 0.0564 | 0.1903 | 0.0682 | 0.2510 | 0.0653 | 0.1984 | 0.1721 | 0.1053 | 0.6172 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0355 | 0.0145 | 0.0548 | 0.0609 | 0.0613 | 0.0522 | 0.0968 | 0.0551 | 0.2194 | 0.0725 | 0.5226 | 0.7449 | 0.0476 | 0.6250 | 0.1746 | 0.2500 | 0.1270 | 0.1250 | 0.2857 | 0.0000 | 0.1746 | 0.0000 | 0.1111 | 0.0000 | 0.0794 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0056 | 0.0278 | 0.0778 | 0.0889 | 0.1611 | 0.2111 | 0.2000 | 0.1722 | 0.0556 | 7 | 7 | 9 | 11 | 11 | 13 | 14 | 16 | 18 | 0.4459 | 0.26 | 0.850 | 0.7731 | 167.2 | 2583.98 | 43505.2 | 785905 | 0.4996 | 0.1549 | 0.0715 | 0.0083 | 0.1464 | 0.0379 | 0.2230 | 0.0592 | 0.2379 | 0.0981 | 0.1747 | 0.1637 | 0.0948 | 0.2202 | 0.0349 | 0.2239 | 0.0166 | 0.1508 | 0.0000 | 0.0379 | 0.0196 | 0.0065 | 0.0267 | 0.0196 | 0.0364 | 0.0224 | 0.0756 | 0.0427 | 0.0907 | 0.0782 | 0.1307 | 0.0941 | 0.1627 | 0.1260 | 0.1956 | 0.2288 | 0.2622 | 0.3816 | 0.0611 | 0.1433 | 0.0630 | 0.1533 | 0.1183 | 0.2067 | 0.1756 | 0.1600 | 0.1584 | 0.1267 | 0.1737 | 0.1000 | 0.1317 | 0.0667 | 0.0954 | 0.0333 | 0.0229 | 0.0100 | 0.0427 | 0.0380 | 0.0617 | 0.1032 | 0.1329 | 0.1696 | 0.1459 | 0.1969 | 0.1091 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 402 | 136 | | 3297 | 12148 | 98.0 | 18.33 | 8.19 | 2.60 | 74 | 80 | 85 | 92 | 97 | 103 | 108 | 114 | 123 | 0.0740 | 899 | 0.685 | 83.76 | 26.42 | 1 | 0.0746 | 246 | 0.0399 | 0.86 | 3.490 | 0.6974 | 9940.2 | 1040000 | 113000000 | 12600000000 | 0.4461 | 0.1984 | 0.0050 | 0.0003 | 0.0077 | 0.0000 | 0.0149 | 0.0019 | 0.0398 | 0.0046 | 0.0430 | 0.0207 | 0.0742 | 0.0377 | 0.0972 | 0.0303 | 0.1470 | 0.0585 | 0.5712 | 0.8460 | 0.0026 | 0.0000 | 0.0018 | 0.0000 | 0.0048 | 0.0015 | 0.0183 | 0.0033 | 0.0202 | 0.0176 | 0.0352 | 0.0303 | 0.0421 | 0.0218 | 0.0546 | 0.0331 | 0.8204 | 0.8923 | 0.0251 | 0.0625 | 0.0309 | 0.0625 | 0.0502 | 0.1719 | 0.0598 | 0.1563 | 0.0927 | 0.1875 | 0.1544 | 0.1406 | 0.1216 | 0.0938 | 0.1564 | 0.0781 | 0.3089 | 0.0469 | 0.0024 | 0.0036 | 0.0134 | 0.0243 | 0.0389 | 0.0584 | 0.0833 | 0.1217 | 0.6539 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0144 | 12.37 | 4.643 | 0.3155 | 73.9 | 721.847 | 7566.38 | 84525.8 | 0.5238 | 0.1413 | 0.0153 | 0.0002 | 0.0771 | 0.0016 | 0.1639 | 0.0070 | 0.2274 | 0.0223 | 0.2309 | 0.0551 | 0.1655 | 0.1102 | 0.0864 | 0.1993 | 0.0283 | 0.3127 | 0.0052 | 0.2916 | 0.0011 | 0.0000 | 0.0072 | 0.0003 | 0.0296 | 0.0015 | 0.0604 | 0.0068 | 0.1020 | 0.0189 | 0.1625 | 0.0400 | 0.2241 | 0.0871 | 0.2509 | 0.2788 | 0.1621 | 0.5666 | 0.0905 | 0.3211 | 0.1651 | 0.2629 | 0.2052 | 0.1761 | 0.1949 | 0.1076 | 0.1565 | 0.0717 | 0.0987 | 0.0351 | 0.0583 | 0.0215 | 0.0222 | 0.0032 | 0.0085 | 0.0008 | 0.0051 | 0.0284 | 0.0735 | 0.1320 | 0.1649 | 0.1938 | 0.1874 | 0.1443 | 0.0706 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 380 | 140 | | 4015 | 11442 | 298.5 | 93.89 | 283.49 | 327.91 | 188 | 224 | 248 | 270 | 290 | 313 | 337 | 371 | 423 | 0.0718 | 821 | 0.641 | 110.89 | 16.16 | 3 | 0.0590 | 237 | 0.0005 | 119.77 | 7.721 | 0.1137 | 97912.3 | 34900000 | 13400000000 | 5490000000000 | 0.4228 | 0.1994 | 0.0000 | 0.0000 | 0.0005 | 0.0003 | 0.0078 | 0.0000 | 0.0352 | 0.0049 | 0.0906 | 0.0391 | 0.1684 | 0.0564 | 0.1361 | 0.0524 | 0.1522 | 0.0795 | 0.4092 | 0.7675 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0135 | 0.0016 | 0.0347 | 0.0237 | 0.0663 | 0.0307 | 0.0579 | 0.0234 | 0.0710 | 0.0373 | 0.7547 | 0.8833 | 0.0011 | 0.0093 | 0.0032 | 0.0023 | 0.0086 | 0.0163 | 0.0452 | 0.0629 | 0.0893 | 0.0979 | 0.1453 | 0.1375 | 0.0969 | 0.1235 | 0.1163 | 0.1142 | 0.4941 | 0.4359 | 0.0005 | 0.0005 | 0.0032 | 0.0244 | 0.0684 | 0.1087 | 0.0976 | 0.1124 | 0.5843 | 18 | 23 | 31 | 69 | 150 | 246 | 370 | 532 | 762 | 0.0260 | 64.88 | 6.232 | 0.4074 | 187886.0 | 166000000 | 173000000000 | 201000000000000 | 0.6183 | 0.1150 | 0.0315 | 0.0018 | 0.0954 | 0.0093 | 0.2028 | 0.0466 | 0.1778 | 0.0888 | 0.1759 | 0.1607 | 0.1389 | 0.1793 | 0.0880 | 0.1474 | 0.0528 | 0.1482 | 0.0370 | 0.2179 | 0.0008 | 0.0000 | 0.0015 | 0.0004 | 0.0054 | 0.0022 | 0.0149 | 0.0104 | 0.0492 | 0.0440 | 0.0677 | 0.0593 | 0.0620 | 0.0557 | 0.0989 | 0.0825 | 0.6996 | 0.7454 | 0.0014 | 0.0000 | 0.0038 | 0.0019 | 0.0049 | 0.0074 | 0.0181 | 0.0211 | 0.0585 | 0.0692 | 0.0937 | 0.0977 | 0.0766 | 0.0922 | 0.1110 | 0.1151 | 0.6320 | 0.5954 | 0.0005 | 0.0026 | 0.0062 | 0.0133 | 0.0554 | 0.0778 | 0.0700 | 0.1011 | 0.6730 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 524 | 141 | | 4317 | 6246 | 463.8 | 114.50 | 71.69 | 106.41 | 339 | 369 | 392 | 415 | 440 | 467 | 500 | 549 | 629 | 0.1005 | 628 | 1.211 | 95.02 | 37.48 | 1 | 0.0563 | 243 | 0.0011 | 40.02 | 7.058 | 0.1884 | 228193.0 | 119000000 | 66600000000 | 39500000000000 | 0.3905 | 0.2504 | 0.0000 | 0.0000 | 0.0012 | 0.0005 | 0.0054 | 0.0005 | 0.0173 | 0.0033 | 0.0695 | 0.0228 | 0.1245 | 0.0415 | 0.1318 | 0.0400 | 0.1690 | 0.0488 | 0.4814 | 0.8426 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0076 | 0.0009 | 0.0334 | 0.0140 | 0.0577 | 0.0244 | 0.0633 | 0.0147 | 0.0882 | 0.0216 | 0.7466 | 0.9244 | 0.0037 | 0.0000 | 0.0049 | 0.0057 | 0.0099 | 0.0345 | 0.0469 | 0.0690 | 0.0877 | 0.1293 | 0.1395 | 0.1264 | 0.1025 | 0.1264 | 0.1173 | 0.1494 | 0.4877 | 0.3592 | 0.0006 | 0.0051 | 0.0130 | 0.0395 | 0.0745 | 0.1072 | 0.0874 | 0.0987 | 0.5742 | 7 | 10 | 12 | 15 | 21 | 31 | 56 | 127 | 227 | 0.0902 | 12.13 | 4.224 | 0.6055 | 16459.4 | 5640000 | 2380000000 | 1160000000000 | 0.4828 | 0.1513 | 0.0532 | 0.0047 | 0.1894 | 0.0235 | 0.2990 | 0.0691 | 0.2359 | 0.1821 | 0.1196 | 0.2323 | 0.0698 | 0.2276 | 0.0266 | 0.1366 | 0.0000 | 0.0754 | 0.0066 | 0.0487 | 0.0000 | 0.0014 | 0.0000 | 0.0014 | 0.0022 | 0.0039 | 0.0129 | 0.0082 | 0.0533 | 0.0488 | 0.0787 | 0.0768 | 0.0566 | 0.0497 | 0.0981 | 0.0888 | 0.6983 | 0.7209 | 0.0000 | 0.0000 | 0.0013 | 0.0021 | 0.0058 | 0.0077 | 0.0154 | 0.0112 | 0.0624 | 0.0732 | 0.0977 | 0.0962 | 0.0585 | 0.0635 | 0.1145 | 0.1123 | 0.6444 | 0.6339 | 0.0000 | 0.0018 | 0.0035 | 0.0183 | 0.0589 | 0.0796 | 0.0654 | 0.0961 | 0.6765 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1160 | 141 | | 3233 | 11358 | 59.9 | 15.14 | 124.51 | 201.52 | 40 | 47 | 52 | 56 | 59 | 63 | 68 | 73 | 80 | 0.0812 | 922 | 1.116 | 66.27 | 24.02 | 8 | 0.0520 | 168 | 0.0039 | 9.71 | 5.841 | 0.3283 | 3816.7 | 256199 | 18000000 | 1310000000 | 0.4210 | 0.2075 | 0.0016 | 0.0007 | 0.0121 | 0.0007 | 0.0236 | 0.0021 | 0.0356 | 0.0084 | 0.0773 | 0.0453 | 0.1135 | 0.0541 | 0.1321 | 0.0699 | 0.1908 | 0.1173 | 0.4134 | 0.7015 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0058 | 0.0007 | 0.0136 | 0.0046 | 0.0342 | 0.0320 | 0.0427 | 0.0346 | 0.0497 | 0.0369 | 0.0730 | 0.0515 | 0.7767 | 0.8398 | 0.0133 | 0.0415 | 0.0146 | 0.0553 | 0.0320 | 0.0968 | 0.0626 | 0.0829 | 0.0786 | 0.1613 | 0.1012 | 0.1705 | 0.1318 | 0.1475 | 0.1491 | 0.1521 | 0.4168 | 0.0922 | 0.0063 | 0.0101 | 0.0184 | 0.0380 | 0.0582 | 0.0671 | 0.0880 | 0.1063 | 0.6076 | 16 | 20 | 23 | 28 | 42 | 71 | 118 | 184 | 325 | 0.0815 | 10.02 | 4.228 | 0.6192 | 56109.0 | 50800000 | 64300000000 | 94700000000000 | 0.6731 | 0.0824 | 0.0382 | 0.0025 | 0.1393 | 0.0177 | 0.1670 | 0.0809 | 0.1460 | 0.1089 | 0.1651 | 0.1648 | 0.1431 | 0.1712 | 0.1002 | 0.1344 | 0.0716 | 0.1363 | 0.0296 | 0.1834 | 0.0000 | 0.0004 | 0.0018 | 0.0020 | 0.0063 | 0.0029 | 0.0266 | 0.0186 | 0.0673 | 0.0669 | 0.0986 | 0.0822 | 0.0819 | 0.0716 | 0.1122 | 0.1042 | 0.6054 | 0.6512 | 0.0004 | 0.0029 | 0.0043 | 0.0062 | 0.0093 | 0.0083 | 0.0377 | 0.0360 | 0.0890 | 0.0989 | 0.1328 | 0.1320 | 0.0800 | 0.0757 | 0.1120 | 0.1105 | 0.5345 | 0.5294 | 0.0012 | 0.0027 | 0.0067 | 0.0307 | 0.0828 | 0.1186 | 0.0791 | 0.1205 | 0.5577 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 568 | 142 | | 3390 | 3676 | 488.2 | 76.89 | 55.99 | 95.47 | 384 | 420 | 448 | 473 | 493 | 513 | 533 | 556 | 587 | 0.1317 | 484 | 0.859 | 109.18 | 23.32 | 5 | 0.0752 | 255 | 0.0012 | 41.51 | 6.959 | 0.2091 | 244289.0 | 125000000 | 65200000000 | 34600000000000 | 0.4456 | 0.2022 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0133 | 0.0009 | 0.0451 | 0.0139 | 0.0863 | 0.0237 | 0.0833 | 0.0160 | 0.1064 | 0.0261 | 0.6638 | 0.9194 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0009 | 0.0220 | 0.0139 | 0.0441 | 0.0237 | 0.0414 | 0.0154 | 0.0588 | 0.0231 | 0.8284 | 0.9230 | 0.0028 | 0.0000 | 0.0113 | 1.0000 | 0.0395 | 0.0000 | 0.1073 | 0.0000 | 0.1638 | 0.0000 | 0.2147 | 0.0000 | 0.1243 | 0.0000 | 0.1356 | 0.0000 | 0.2006 | 0.0000 | 0.0006 | 0.0017 | 0.0045 | 0.0195 | 0.0658 | 0.1155 | 0.1016 | 0.1267 | 0.5642 | 9 | 11 | 12 | 14 | 17 | 20 | 25 | 75 | 169 | 0.1554 | 6.68 | 3.147 | 0.7267 | 12247.2 | 4240000 | 1770000000 | 834000000000 | 0.4752 | 0.1492 | 0.0192 | 0.0284 | 0.0769 | 0.0355 | 0.1731 | 0.1277 | 0.3462 | 0.1489 | 0.1346 | 0.1915 | 0.1346 | 0.1773 | 0.1154 | 0.1206 | 0.0000 | 0.0709 | 0.0000 | 0.0993 | 0.0000 | 0.0046 | 0.0025 | 0.0058 | 0.0012 | 0.0116 | 0.0037 | 0.0127 | 0.0160 | 0.0197 | 0.0197 | 0.0313 | 0.0271 | 0.0174 | 0.0406 | 0.0440 | 0.8892 | 0.8530 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0028 | 0.0039 | 0.0083 | 0.0211 | 0.0221 | 0.0316 | 0.0456 | 0.0395 | 0.0415 | 0.0684 | 0.0692 | 0.8329 | 0.8105 | 0.0000 | 0.0000 | 0.0013 | 0.0038 | 0.0189 | 0.0215 | 0.0278 | 0.0556 | 0.8712 |