High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1097 | 401 | | 5619 | 10511 | 100.4 | 25.69 | 150.94 | 167.26 | 71 | 79 | 86 | 92 | 97 | 103 | 110 | 119 | 132 | 0.0786 | 826 | 0.983 | 96.05 | 27.31 | 1 | 0.0418 | 235 | 0.0033 | 15.27 | 6.069 | 0.2967 | 10734.1 | 1230000 | 151000000 | 19900000000 | 0.4514 | 0.2026 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0093 | 0.0000 | 0.0335 | 0.0025 | 0.0924 | 0.0231 | 0.1475 | 0.0450 | 0.1673 | 0.0550 | 0.1991 | 0.0865 | 0.3487 | 0.7879 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0000 | 0.0089 | 0.0002 | 0.0392 | 0.0149 | 0.0643 | 0.0223 | 0.0770 | 0.0225 | 0.1061 | 0.0415 | 0.7020 | 0.8987 | 0.0103 | 0.0074 | 0.0197 | 0.0245 | 0.0310 | 0.0515 | 0.0874 | 0.0711 | 0.1400 | 0.1985 | 0.1805 | 0.1642 | 0.1184 | 0.1201 | 0.1391 | 0.1569 | 0.2735 | 0.2059 | 0.0012 | 0.0051 | 0.0125 | 0.0446 | 0.0896 | 0.1405 | 0.1151 | 0.1526 | 0.4387 | 11 | 17 | 32 | 53 | 79 | 117 | 181 | 290 | 415 | 0.0097 | 71.41 | 6.470 | 0.3608 | 50757.6 | 22700000 | 11700000000 | 6580000000000 | 0.5255 | 0.1681 | 0.0205 | 0.0024 | 0.1212 | 0.0122 | 0.2269 | 0.0538 | 0.1561 | 0.1204 | 0.1448 | 0.1703 | 0.1458 | 0.1689 | 0.0791 | 0.1385 | 0.0565 | 0.1434 | 0.0493 | 0.1899 | 0.0005 | 0.0004 | 0.0015 | 0.0008 | 0.0056 | 0.0018 | 0.0121 | 0.0135 | 0.0522 | 0.0488 | 0.0869 | 0.0725 | 0.0689 | 0.0674 | 0.0959 | 0.0926 | 0.6765 | 0.7021 | 0.0000 | 0.0007 | 0.0022 | 0.0011 | 0.0060 | 0.0049 | 0.0133 | 0.0226 | 0.0616 | 0.0560 | 0.1042 | 0.1173 | 0.0801 | 0.0920 | 0.1087 | 0.1117 | 0.6238 | 0.5937 | 0.0014 | 0.0025 | 0.0061 | 0.0150 | 0.0574 | 0.0872 | 0.0738 | 0.0955 | 0.6611 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 122 | 891 | | 5327 | 11696 | 148.0 | 43.59 | 217.70 | 199.22 | 99 | 112 | 123 | 132 | 142 | 151 | 163 | 179 | 203 | 0.0892 | 1043 | 1.215 | 95.34 | 38.64 | 1 | 0.0466 | 248 | 0.0014 | 41.30 | 6.881 | 0.2047 | 23789.2 | 4180000 | 807000000 | 172000000000 | 0.4266 | 0.2289 | 0.0000 | 0.0000 | 0.0056 | 0.0000 | 0.0251 | 0.0013 | 0.0471 | 0.0047 | 0.1157 | 0.0325 | 0.1666 | 0.0629 | 0.1649 | 0.0713 | 0.1997 | 0.1120 | 0.2754 | 0.7151 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0038 | 0.0006 | 0.0121 | 0.0008 | 0.0476 | 0.0188 | 0.0784 | 0.0323 | 0.0758 | 0.0298 | 0.1162 | 0.0531 | 0.6657 | 0.8647 | 0.0082 | 0.0150 | 0.0082 | 0.0107 | 0.0245 | 0.0515 | 0.0927 | 0.1180 | 0.1455 | 0.1888 | 0.1936 | 0.1996 | 0.1264 | 0.1245 | 0.1564 | 0.1352 | 0.2445 | 0.1567 | 0.0017 | 0.0038 | 0.0137 | 0.0384 | 0.0970 | 0.1482 | 0.1179 | 0.1521 | 0.4272 | 20 | 42 | 72 | 110 | 157 | 216 | 283 | 375 | 516 | 0.0025 | 101.46 | 7.379 | 0.2318 | 87079.5 | 45700000 | 28000000000 | 19200000000000 | 0.4833 | 0.1693 | 0.0350 | 0.0024 | 0.1038 | 0.0141 | 0.1931 | 0.0587 | 0.1431 | 0.1069 | 0.1600 | 0.1598 | 0.1213 | 0.1625 | 0.1000 | 0.1305 | 0.0781 | 0.1354 | 0.0656 | 0.2298 | 0.0009 | 0.0005 | 0.0017 | 0.0025 | 0.0061 | 0.0045 | 0.0160 | 0.0176 | 0.0575 | 0.0550 | 0.0955 | 0.0812 | 0.0699 | 0.0655 | 0.1043 | 0.0953 | 0.6482 | 0.6780 | 0.0013 | 0.0012 | 0.0039 | 0.0053 | 0.0078 | 0.0112 | 0.0234 | 0.0287 | 0.0793 | 0.0765 | 0.1139 | 0.1255 | 0.0886 | 0.0921 | 0.1219 | 0.1240 | 0.5599 | 0.5353 | 0.0011 | 0.0013 | 0.0071 | 0.0174 | 0.0656 | 0.1025 | 0.0861 | 0.1177 | 0.6012 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 974 | 491 | | 2075 | 6138 | 79.2 | 16.85 | 226.62 | 224.68 | 59 | 65 | 70 | 74 | 77 | 82 | 86 | 93 | 102 | 0.0632 | 388 | 0.768 | 127.88 | 34.79 | 1 | 0.1566 | 325 | 0.0032 | 15.64 | 6.011 | 0.2726 | 6562.2 | 567309 | 51100000 | 4800000000 | 0.4688 | 0.1916 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0073 | 0.0005 | 0.0278 | 0.0010 | 0.0805 | 0.0234 | 0.1426 | 0.0426 | 0.1500 | 0.0483 | 0.2004 | 0.0701 | 0.3899 | 0.8141 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0063 | 0.0000 | 0.0322 | 0.0138 | 0.0679 | 0.0256 | 0.0621 | 0.0177 | 0.1059 | 0.0290 | 0.7238 | 0.9140 | 0.0081 | 0.0370 | 0.0270 | 0.0278 | 0.0377 | 0.0926 | 0.0916 | 0.0833 | 0.1456 | 0.1759 | 0.1806 | 0.2407 | 0.1294 | 0.1204 | 0.1240 | 0.1852 | 0.2561 | 0.0370 | 0.0030 | 0.0071 | 0.0163 | 0.0346 | 0.0925 | 0.1209 | 0.1189 | 0.1423 | 0.4644 | 24 | 43 | 68 | 98 | 138 | 204 | 294 | 397 | 550 | 0.0072 | 49.76 | 6.356 | 0.3422 | 101826.0 | 62200000 | 45000000000 | 36400000000000 | 0.4500 | 0.1910 | 0.0311 | 0.0000 | 0.1627 | 0.0071 | 0.2825 | 0.0767 | 0.1686 | 0.1526 | 0.1361 | 0.1859 | 0.1124 | 0.2314 | 0.0503 | 0.1313 | 0.0355 | 0.0987 | 0.0207 | 0.1164 | 0.0008 | 0.0000 | 0.0023 | 0.0013 | 0.0011 | 0.0016 | 0.0106 | 0.0107 | 0.0513 | 0.0417 | 0.1124 | 0.1059 | 0.0724 | 0.0672 | 0.1116 | 0.0820 | 0.6376 | 0.6897 | 0.0000 | 0.0012 | 0.0005 | 0.0030 | 0.0056 | 0.0077 | 0.0192 | 0.0195 | 0.0709 | 0.0936 | 0.1478 | 0.1647 | 0.1063 | 0.1043 | 0.1184 | 0.1345 | 0.5314 | 0.4716 | 0.0004 | 0.0013 | 0.0053 | 0.0149 | 0.0605 | 0.1329 | 0.0925 | 0.1136 | 0.5785 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1197 | 726 | | 3699 | 9192 | 137.4 | 44.39 | 37.17 | 36.11 | 98 | 107 | 113 | 119 | 127 | 135 | 146 | 160 | 187 | 0.0926 | 851 | 1.180 | 107.28 | 41.01 | 1 | 0.0746 | 276 | 0.0024 | 30.51 | 6.416 | 0.2449 | 20843.7 | 3610000 | 733000000 | 177000000000 | 0.4112 | 0.2401 | 0.0009 | 0.0003 | 0.0037 | 0.0006 | 0.0107 | 0.0009 | 0.0409 | 0.0027 | 0.0991 | 0.0285 | 0.1647 | 0.0612 | 0.1629 | 0.0558 | 0.2010 | 0.0876 | 0.3160 | 0.7623 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0050 | 0.0000 | 0.0210 | 0.0014 | 0.0522 | 0.0177 | 0.0878 | 0.0343 | 0.0906 | 0.0296 | 0.1372 | 0.0500 | 0.6048 | 0.8670 | 0.0060 | 0.0031 | 0.0105 | 0.0031 | 0.0180 | 0.0251 | 0.0481 | 0.0721 | 0.1008 | 0.1755 | 0.1474 | 0.1850 | 0.1158 | 0.1129 | 0.1549 | 0.1348 | 0.3985 | 0.2884 | 0.0049 | 0.0084 | 0.0182 | 0.0477 | 0.0869 | 0.1170 | 0.0953 | 0.0988 | 0.5228 | 9 | 13 | 17 | 21 | 25 | 32 | 40 | 53 | 80 | 0.0260 | 5.48 | 4.415 | 0.5610 | 2685.3 | 330423 | 59700000 | 14100000000 | 0.5938 | 0.1120 | 0.0235 | 0.0088 | 0.0780 | 0.0186 | 0.1751 | 0.0368 | 0.2151 | 0.0862 | 0.2240 | 0.1372 | 0.1421 | 0.1696 | 0.0882 | 0.1863 | 0.0406 | 0.1875 | 0.0133 | 0.1690 | 0.0060 | 0.0053 | 0.0070 | 0.0086 | 0.0141 | 0.0129 | 0.0319 | 0.0244 | 0.0718 | 0.0561 | 0.1115 | 0.0821 | 0.1027 | 0.0929 | 0.1364 | 0.1305 | 0.5185 | 0.5871 | 0.0033 | 0.0083 | 0.0129 | 0.0119 | 0.0220 | 0.0217 | 0.0407 | 0.0620 | 0.1073 | 0.1168 | 0.1401 | 0.1302 | 0.1052 | 0.1111 | 0.1393 | 0.1292 | 0.4291 | 0.4088 | 0.0032 | 0.0106 | 0.0122 | 0.0448 | 0.0860 | 0.1246 | 0.1159 | 0.1259 | 0.4767 | ||
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 274 | 724 | | 833 | 13982 | 37.7 | 9.22 | 181.15 | 216.84 | 28 | 30 | 32 | 34 | 36 | 38 | 40 | 44 | 50 | 0.0473 | 662 | 1.199 | 23.54 | 8.94 | 3 | 0.0732 | 61 | 0.0229 | 2.86 | 4.160 | 0.4919 | 1505.4 | 64089 | 2920000 | 142000000 | 0.4024 | 0.2135 | 0.0039 | 0.0000 | 0.0197 | 0.0000 | 0.0197 | 0.0000 | 0.0907 | 0.0156 | 0.1243 | 0.0650 | 0.1460 | 0.0728 | 0.1913 | 0.1027 | 0.2012 | 0.1352 | 0.2032 | 0.6086 | 0.0031 | 0.0000 | 0.0108 | 0.0000 | 0.0154 | 0.0000 | 0.0555 | 0.0132 | 0.0709 | 0.0505 | 0.0755 | 0.0457 | 0.1248 | 0.0721 | 0.1171 | 0.0805 | 0.5270 | 0.7380 | 0.0141 | 0.0317 | 0.0070 | 0.0317 | 0.0211 | 0.0317 | 0.0845 | 0.0794 | 0.1268 | 0.1746 | 0.1479 | 0.1587 | 0.0775 | 0.1429 | 0.1831 | 0.1111 | 0.3380 | 0.2381 | 0.0089 | 0.0417 | 0.0357 | 0.0774 | 0.0923 | 0.1220 | 0.1042 | 0.1399 | 0.3780 | 13 | 15 | 18 | 25 | 72 | 155 | 247 | 356 | 505 | 0.1047 | 25.13 | 4.988 | 0.5234 | 79833.1 | 46100000 | 31400000000 | 24300000000000 | 0.5786 | 0.1133 | 0.0295 | 0.0009 | 0.1412 | 0.0151 | 0.2513 | 0.0722 | 0.1854 | 0.1324 | 0.1750 | 0.2019 | 0.1161 | 0.2027 | 0.0537 | 0.1479 | 0.0286 | 0.1209 | 0.0191 | 0.1062 | 0.0005 | 0.0000 | 0.0021 | 0.0008 | 0.0031 | 0.0022 | 0.0102 | 0.0085 | 0.0401 | 0.0383 | 0.0610 | 0.0504 | 0.0571 | 0.0510 | 0.0875 | 0.0745 | 0.7384 | 0.7744 | 0.0004 | 0.0002 | 0.0013 | 0.0015 | 0.0054 | 0.0051 | 0.0173 | 0.0245 | 0.0542 | 0.0646 | 0.0886 | 0.0970 | 0.0864 | 0.1030 | 0.1156 | 0.1191 | 0.6309 | 0.5849 | 0.0004 | 0.0035 | 0.0025 | 0.0146 | 0.0434 | 0.0766 | 0.0726 | 0.0991 | 0.6873 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 364 | | 5225 | 12570 | 114.6 | 29.24 | 148.81 | 175.19 | 84 | 92 | 98 | 104 | 110 | 116 | 124 | 134 | 151 | 0.0699 | 879 | 0.810 | 72.24 | 18.44 | 1 | 0.0389 | 203 | 0.0030 | 17.44 | 6.162 | 0.2786 | 13983.3 | 1830000 | 261000000 | 40800000000 | 0.4284 | 0.2226 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0091 | 0.0002 | 0.0324 | 0.0035 | 0.0800 | 0.0215 | 0.1378 | 0.0503 | 0.1584 | 0.0530 | 0.2021 | 0.0722 | 0.3790 | 0.7993 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0024 | 0.0000 | 0.0124 | 0.0006 | 0.0398 | 0.0144 | 0.0640 | 0.0290 | 0.0688 | 0.0226 | 0.1076 | 0.0342 | 0.7040 | 0.8992 | 0.0056 | 0.0087 | 0.0111 | 0.0173 | 0.0356 | 0.0376 | 0.0934 | 0.1272 | 0.1446 | 0.1821 | 0.1758 | 0.1792 | 0.1224 | 0.1098 | 0.1313 | 0.1156 | 0.2803 | 0.2225 | 0.0027 | 0.0045 | 0.0145 | 0.0377 | 0.0921 | 0.1403 | 0.1135 | 0.1589 | 0.4358 | 11 | 15 | 26 | 46 | 79 | 124 | 182 | 256 | 391 | 0.0134 | 67.23 | 6.423 | 0.3671 | 52832.2 | 26600000 | 16100000000 | 11000000000000 | 0.5002 | 0.1902 | 0.0463 | 0.0026 | 0.1259 | 0.0198 | 0.2117 | 0.0847 | 0.1593 | 0.1067 | 0.1464 | 0.1418 | 0.1017 | 0.1687 | 0.1017 | 0.1354 | 0.0637 | 0.1313 | 0.0432 | 0.2090 | 0.0002 | 0.0000 | 0.0006 | 0.0005 | 0.0035 | 0.0017 | 0.0186 | 0.0129 | 0.0574 | 0.0525 | 0.0893 | 0.0815 | 0.0763 | 0.0603 | 0.1007 | 0.0887 | 0.6535 | 0.7020 | 0.0005 | 0.0012 | 0.0052 | 0.0030 | 0.0073 | 0.0094 | 0.0250 | 0.0301 | 0.0725 | 0.0779 | 0.1207 | 0.1181 | 0.0816 | 0.0907 | 0.1035 | 0.1026 | 0.5837 | 0.5670 | 0.0000 | 0.0011 | 0.0045 | 0.0194 | 0.0690 | 0.1067 | 0.0853 | 0.1053 | 0.6087 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1092 | 85 | | 5449 | 11450 | 95.0 | 23.16 | 86.45 | 60.42 | 71 | 77 | 81 | 86 | 91 | 95 | 101 | 110 | 125 | 0.0779 | 892 | 0.747 | 88.84 | 18.03 | 1 | 0.0376 | 205 | 0.0045 | 11.97 | 5.782 | 0.3166 | 9560.2 | 1030000 | 119000000 | 14900000000 | 0.4517 | 0.1982 | 0.0017 | 0.0000 | 0.0031 | 0.0000 | 0.0068 | 0.0002 | 0.0214 | 0.0018 | 0.0749 | 0.0225 | 0.1219 | 0.0393 | 0.1611 | 0.0466 | 0.2022 | 0.0826 | 0.4069 | 0.8069 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0029 | 0.0000 | 0.0120 | 0.0006 | 0.0334 | 0.0144 | 0.0484 | 0.0215 | 0.0776 | 0.0164 | 0.1074 | 0.0354 | 0.7154 | 0.9118 | 0.0096 | 0.0216 | 0.0160 | 0.0377 | 0.0310 | 0.0377 | 0.0652 | 0.0970 | 0.1485 | 0.1375 | 0.1485 | 0.1563 | 0.1239 | 0.1186 | 0.1528 | 0.1456 | 0.3045 | 0.2480 | 0.0022 | 0.0066 | 0.0254 | 0.0521 | 0.0902 | 0.1139 | 0.1248 | 0.1323 | 0.4525 | 21 | 33 | 45 | 59 | 73 | 90 | 110 | 133 | 169 | 0.0064 | 12.20 | 5.702 | 0.3894 | 11125.0 | 1840000 | 360000000 | 80100000000 | 0.5551 | 0.1175 | 0.0169 | 0.0024 | 0.0852 | 0.0089 | 0.1933 | 0.0316 | 0.2046 | 0.0842 | 0.1860 | 0.1444 | 0.1445 | 0.1944 | 0.0848 | 0.1671 | 0.0580 | 0.1675 | 0.0268 | 0.1994 | 0.0005 | 0.0011 | 0.0025 | 0.0020 | 0.0062 | 0.0051 | 0.0237 | 0.0164 | 0.0697 | 0.0496 | 0.1043 | 0.0775 | 0.0994 | 0.0776 | 0.1410 | 0.1147 | 0.5528 | 0.6561 | 0.0008 | 0.0052 | 0.0066 | 0.0098 | 0.0138 | 0.0265 | 0.0517 | 0.0622 | 0.1115 | 0.1306 | 0.1502 | 0.1614 | 0.1351 | 0.1383 | 0.1523 | 0.1453 | 0.3780 | 0.3206 | 0.0019 | 0.0031 | 0.0080 | 0.0331 | 0.0932 | 0.1245 | 0.1171 | 0.1566 | 0.4623 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 818 | 411 | | 1111 | 7364 | 67.7 | 19.08 | 51.50 | 75.73 | 43 | 51 | 58 | 63 | 67 | 72 | 77 | 83 | 92 | 0.0743 | 547 | 0.895 | 205.46 | 68.66 | 1 | 0.5041 | 560 | 0.0025 | 26.29 | 6.146 | 0.2030 | 4951.3 | 386036 | 31800000 | 2760000000 | 0.4919 | 0.1558 | 0.0017 | 0.0000 | 0.0084 | 0.0000 | 0.0506 | 0.0042 | 0.0759 | 0.0116 | 0.1433 | 0.0582 | 0.1855 | 0.0857 | 0.1484 | 0.1228 | 0.2024 | 0.1185 | 0.1838 | 0.5989 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0237 | 0.0078 | 0.0580 | 0.0447 | 0.1018 | 0.0438 | 0.0994 | 0.0720 | 0.1515 | 0.0730 | 0.5657 | 0.7588 | 0.0198 | 0.0241 | 0.0238 | 0.0361 | 0.0437 | 0.1566 | 0.1032 | 0.2289 | 0.1468 | 0.1325 | 0.2103 | 0.1687 | 0.1071 | 0.0602 | 0.1151 | 0.0482 | 0.2302 | 0.1446 | 0.0000 | 0.0036 | 0.0163 | 0.0470 | 0.1501 | 0.1410 | 0.1338 | 0.1591 | 0.3490 | 15 | 17 | 18 | 21 | 24 | 29 | 39 | 59 | 117 | 0.2303 | 3.57 | 2.698 | 0.7805 | 8387.2 | 2780000 | 1260000000 | 683000000000 | 0.4695 | 0.1988 | 0.0338 | 0.0076 | 0.1132 | 0.0146 | 0.2294 | 0.0419 | 0.1779 | 0.1017 | 0.1647 | 0.1773 | 0.1250 | 0.1919 | 0.0632 | 0.1582 | 0.0662 | 0.1264 | 0.0265 | 0.1804 | 0.0057 | 0.0035 | 0.0047 | 0.0053 | 0.0095 | 0.0114 | 0.0218 | 0.0252 | 0.0816 | 0.0650 | 0.1044 | 0.0919 | 0.0745 | 0.0831 | 0.1144 | 0.1136 | 0.5833 | 0.6010 | 0.0007 | 0.0016 | 0.0042 | 0.0032 | 0.0049 | 0.0048 | 0.0329 | 0.0322 | 0.0988 | 0.0893 | 0.1142 | 0.1376 | 0.0883 | 0.0837 | 0.1065 | 0.1255 | 0.5494 | 0.5221 | 0.0029 | 0.0041 | 0.0088 | 0.0269 | 0.0779 | 0.1265 | 0.0715 | 0.1154 | 0.5659 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1246 | 581 | | 5724 | 10893 | 64.5 | 15.39 | 236.73 | 211.09 | 47 | 52 | 56 | 60 | 63 | 66 | 70 | 75 | 83 | 0.1007 | 1097 | 0.634 | 184.57 | 34.06 | 2 | 0.0786 | 450 | 0.0087 | 5.31 | 5.104 | 0.4181 | 4403.3 | 318930 | 24700000 | 2070000000 | 0.5293 | 0.1575 | 0.0011 | 0.0000 | 0.0029 | 0.0002 | 0.0149 | 0.0025 | 0.0344 | 0.0079 | 0.0831 | 0.0249 | 0.1403 | 0.0624 | 0.1470 | 0.0543 | 0.2027 | 0.0933 | 0.3736 | 0.7545 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0073 | 0.0014 | 0.0168 | 0.0048 | 0.0432 | 0.0173 | 0.0852 | 0.0464 | 0.0787 | 0.0324 | 0.1224 | 0.0582 | 0.6454 | 0.8396 | 0.0146 | 0.0251 | 0.0258 | 0.0282 | 0.0538 | 0.0219 | 0.0806 | 0.1066 | 0.1333 | 0.1818 | 0.1445 | 0.1630 | 0.1333 | 0.1348 | 0.1344 | 0.1285 | 0.2800 | 0.2100 | 0.0049 | 0.0125 | 0.0245 | 0.0623 | 0.1061 | 0.1303 | 0.1318 | 0.1477 | 0.3799 | 16 | 25 | 64 | 130 | 196 | 261 | 329 | 412 | 529 | 0.0116 | 86.41 | 6.934 | 0.2713 | 100595.0 | 54000000 | 33700000000 | 23600000000000 | 0.4576 | 0.1893 | 0.0320 | 0.0013 | 0.1436 | 0.0119 | 0.2339 | 0.0569 | 0.1831 | 0.1264 | 0.1737 | 0.1747 | 0.1260 | 0.2062 | 0.0652 | 0.1467 | 0.0332 | 0.1364 | 0.0094 | 0.1396 | 0.0005 | 0.0003 | 0.0027 | 0.0008 | 0.0034 | 0.0019 | 0.0151 | 0.0095 | 0.0589 | 0.0467 | 0.0943 | 0.0811 | 0.0861 | 0.0713 | 0.1289 | 0.1061 | 0.6100 | 0.6824 | 0.0003 | 0.0012 | 0.0025 | 0.0031 | 0.0076 | 0.0127 | 0.0227 | 0.0347 | 0.0882 | 0.1018 | 0.1372 | 0.1535 | 0.1175 | 0.1148 | 0.1447 | 0.1528 | 0.4794 | 0.4254 | 0.0017 | 0.0015 | 0.0040 | 0.0185 | 0.0733 | 0.1092 | 0.0968 | 0.1432 | 0.5521 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1257 | 588 | | 6871 | 2051 | 137.3 | 25.65 | 90.04 | 55.86 | 104 | 115 | 123 | 130 | 137 | 144 | 150 | 159 | 170 | 0.3667 | 752 | 0.924 | 92.78 | 24.76 | 1 | 0.0342 | 235 | 0.0024 | 19.20 | 6.305 | 0.2542 | 19504.3 | 2860000 | 432000000 | 67100000000 | 0.4703 | 0.1831 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0058 | 0.0004 | 0.0210 | 0.0004 | 0.0599 | 0.0142 | 0.1283 | 0.0298 | 0.1440 | 0.0322 | 0.2039 | 0.0594 | 0.4358 | 0.8634 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0004 | 0.0066 | 0.0001 | 0.0250 | 0.0117 | 0.0591 | 0.0222 | 0.0521 | 0.0126 | 0.0901 | 0.0273 | 0.7638 | 0.9256 | 0.0138 | 0.0690 | 0.0324 | 0.0621 | 0.0482 | 0.1724 | 0.1455 | 0.2621 | 0.1888 | 0.1862 | 0.1642 | 0.1517 | 0.1445 | 0.0759 | 0.1259 | 0.0207 | 0.1367 | 0.0000 | 0.0006 | 0.0048 | 0.0097 | 0.0311 | 0.0829 | 0.1268 | 0.1317 | 0.1622 | 0.4503 | 25 | 40 | 54 | 69 | 83 | 97 | 113 | 133 | 160 | 0.0056 | 13.56 | 5.596 | 0.3618 | 11225.5 | 1750000 | 329000000 | 72100000000 | 0.5016 | 0.1610 | 0.0194 | 0.0010 | 0.1282 | 0.0104 | 0.2039 | 0.0604 | 0.1942 | 0.1093 | 0.1515 | 0.1894 | 0.1612 | 0.2362 | 0.0971 | 0.1592 | 0.0291 | 0.1228 | 0.0155 | 0.1113 | 0.0008 | 0.0007 | 0.0067 | 0.0028 | 0.0193 | 0.0104 | 0.0469 | 0.0291 | 0.1182 | 0.0992 | 0.1869 | 0.1881 | 0.1090 | 0.1013 | 0.1534 | 0.1367 | 0.3588 | 0.4316 | 0.0074 | 0.0125 | 0.0251 | 0.0250 | 0.0457 | 0.0813 | 0.0959 | 0.1479 | 0.1504 | 0.1583 | 0.2021 | 0.1813 | 0.1239 | 0.1458 | 0.1431 | 0.1333 | 0.2065 | 0.1146 | 0.0022 | 0.0108 | 0.0390 | 0.0683 | 0.1354 | 0.1788 | 0.1365 | 0.1560 | 0.2730 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 780 | 643 | | 4246 | 9503 | 153.2 | 43.23 | 163.95 | 111.35 | 107 | 118 | 127 | 135 | 144 | 155 | 167 | 184 | 213 | 0.0930 | 884 | 1.215 | 66.84 | 30.36 | 1 | 0.0445 | 189 | 0.0016 | 33.38 | 6.721 | 0.2068 | 25324.3 | 4540000 | 884000000 | 186000000000 | 0.4222 | 0.2177 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0065 | 0.0005 | 0.0285 | 0.0037 | 0.1085 | 0.0264 | 0.1876 | 0.0650 | 0.1746 | 0.0647 | 0.2040 | 0.0836 | 0.2891 | 0.7561 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0002 | 0.0110 | 0.0012 | 0.0397 | 0.0171 | 0.0784 | 0.0293 | 0.0800 | 0.0238 | 0.1178 | 0.0358 | 0.6711 | 0.8927 | 0.0023 | 0.0000 | 0.0047 | 0.0049 | 0.0140 | 0.0196 | 0.0756 | 0.1225 | 0.1465 | 0.1716 | 0.1686 | 0.2059 | 0.1128 | 0.1152 | 0.1419 | 0.1127 | 0.3337 | 0.2475 | 0.0011 | 0.0022 | 0.0056 | 0.0332 | 0.0917 | 0.1507 | 0.1074 | 0.1277 | 0.4803 | 49 | 74 | 95 | 116 | 139 | 164 | 198 | 245 | 310 | 0.0019 | 44.15 | 6.783 | 0.2632 | 39278.6 | 12800000 | 5480000000 | 3000000000000 | 0.5562 | 0.1215 | 0.0241 | 0.0012 | 0.0805 | 0.0056 | 0.1411 | 0.0391 | 0.1416 | 0.0770 | 0.1754 | 0.1299 | 0.1546 | 0.1697 | 0.1157 | 0.1456 | 0.0995 | 0.1528 | 0.0676 | 0.2792 | 0.0014 | 0.0002 | 0.0026 | 0.0009 | 0.0069 | 0.0057 | 0.0242 | 0.0137 | 0.0746 | 0.0545 | 0.1063 | 0.0876 | 0.0950 | 0.0778 | 0.1295 | 0.1115 | 0.5595 | 0.6480 | 0.0031 | 0.0018 | 0.0045 | 0.0054 | 0.0118 | 0.0145 | 0.0478 | 0.0559 | 0.1069 | 0.1335 | 0.1491 | 0.1807 | 0.1301 | 0.1326 | 0.1557 | 0.1685 | 0.3910 | 0.3070 | 0.0018 | 0.0050 | 0.0089 | 0.0404 | 0.0908 | 0.1409 | 0.1049 | 0.1375 | 0.4699 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 892 | 528 | | 438 | 4290 | 99.4 | 30.58 | 45.69 | 79.25 | 57 | 73 | 84 | 93 | 98 | 106 | 113 | 122 | 143 | 0.0991 | 425 | 0.186 | 244.68 | 30.23 | 3 | 2.7374 | 1199 | 0.0033 | 47.98 | 5.825 | 0.1324 | 10807.1 | 1270000 | 158000000 | 20800000000 | 0.3355 | 0.2955 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0000 | 0.0727 | 0.0060 | 0.1182 | 0.0925 | 0.1318 | 0.0896 | 0.1591 | 0.0985 | 0.2045 | 0.1254 | 0.3045 | 0.5881 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0123 | 0.0026 | 0.0679 | 0.0596 | 0.0494 | 0.0570 | 0.0710 | 0.0440 | 0.0802 | 0.0648 | 0.7160 | 0.7720 | 0.0096 | 0.0000 | 0.0192 | 0.0000 | 0.0096 | 0.0392 | 0.0288 | 0.0196 | 0.1154 | 0.1961 | 0.1250 | 0.1765 | 0.0962 | 0.1176 | 0.1731 | 0.2745 | 0.4231 | 0.1765 | 0.0046 | 0.0092 | 0.0184 | 0.0276 | 0.0783 | 0.1014 | 0.1060 | 0.1382 | 0.5161 | 14 | 17 | 19 | 23 | 26 | 30 | 36 | 48 | 74 | 0.2037 | 1.21 | 2.394 | 0.8309 | 8367.0 | 4140000 | 2720000000 | 1970000000000 | 0.5493 | 0.1523 | 0.0193 | 0.0111 | 0.0456 | 0.0222 | 0.1298 | 0.0341 | 0.1333 | 0.0632 | 0.1754 | 0.1091 | 0.2140 | 0.1543 | 0.1386 | 0.1508 | 0.0930 | 0.1737 | 0.0509 | 0.2814 | 0.0072 | 0.0081 | 0.0087 | 0.0163 | 0.0223 | 0.0229 | 0.0405 | 0.0366 | 0.0692 | 0.0630 | 0.0922 | 0.0885 | 0.0978 | 0.0976 | 0.1065 | 0.1205 | 0.5556 | 0.5465 | 0.0029 | 0.0000 | 0.0116 | 0.0303 | 0.0305 | 0.0227 | 0.0349 | 0.0360 | 0.0799 | 0.0833 | 0.1105 | 0.1174 | 0.1017 | 0.0947 | 0.1366 | 0.1193 | 0.4913 | 0.4962 | 0.0022 | 0.0076 | 0.0174 | 0.0239 | 0.0827 | 0.0914 | 0.1012 | 0.1164 | 0.5571 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 118 | 415 | | 5291 | 13931 | 133.5 | 31.83 | 201.37 | 181.71 | 100 | 107 | 114 | 119 | 126 | 134 | 144 | 157 | 178 | 0.0743 | 1035 | 1.075 | 91.53 | 27.73 | 2 | 0.0433 | 229 | 0.0025 | 21.43 | 6.360 | 0.2445 | 18826.4 | 2820000 | 448000000 | 75800000000 | 0.4311 | 0.2131 | 0.0015 | 0.0000 | 0.0042 | 0.0000 | 0.0097 | 0.0006 | 0.0303 | 0.0025 | 0.0739 | 0.0239 | 0.1357 | 0.0482 | 0.1636 | 0.0458 | 0.2090 | 0.0658 | 0.3720 | 0.8132 | 0.0012 | 0.0000 | 0.0028 | 0.0000 | 0.0044 | 0.0000 | 0.0131 | 0.0009 | 0.0332 | 0.0117 | 0.0592 | 0.0263 | 0.0788 | 0.0152 | 0.1106 | 0.0243 | 0.6966 | 0.9216 | 0.0062 | 0.0078 | 0.0175 | 0.0337 | 0.0287 | 0.0285 | 0.0585 | 0.0933 | 0.1181 | 0.1917 | 0.1694 | 0.1839 | 0.1201 | 0.1503 | 0.1427 | 0.1554 | 0.3388 | 0.1554 | 0.0072 | 0.0031 | 0.0143 | 0.0371 | 0.0809 | 0.1314 | 0.1033 | 0.1404 | 0.4823 | 25 | 47 | 73 | 108 | 146 | 194 | 256 | 337 | 458 | 0.0034 | 64.02 | 6.918 | 0.3096 | 73564.5 | 36500000 | 22100000000 | 15400000000000 | 0.6227 | 0.0824 | 0.0134 | 0.0036 | 0.0711 | 0.0072 | 0.1619 | 0.0323 | 0.1753 | 0.0736 | 0.1984 | 0.1406 | 0.1681 | 0.1996 | 0.1071 | 0.1572 | 0.0644 | 0.1658 | 0.0403 | 0.2202 | 0.0011 | 0.0011 | 0.0023 | 0.0013 | 0.0063 | 0.0053 | 0.0173 | 0.0127 | 0.0541 | 0.0396 | 0.0851 | 0.0756 | 0.0699 | 0.0574 | 0.0977 | 0.0911 | 0.6663 | 0.7158 | 0.0014 | 0.0014 | 0.0032 | 0.0035 | 0.0083 | 0.0127 | 0.0236 | 0.0343 | 0.0730 | 0.0863 | 0.1137 | 0.1284 | 0.0955 | 0.1055 | 0.1286 | 0.1320 | 0.5528 | 0.4959 | 0.0017 | 0.0045 | 0.0102 | 0.0202 | 0.0633 | 0.0900 | 0.0787 | 0.1201 | 0.6112 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 844 | | 2908 | 15413 | 16.0 | 5.68 | 6.17 | 2.21 | 10 | 12 | 13 | 14 | 15 | 16 | 18 | 19 | 22 | 0.0804 | 1239 | 1.278 | 24.04 | 7.81 | 0 | 0.0193 | 56 | 0.0081 | 8.98 | 5.211 | 0.3653 | 289.8 | 6020.69 | 146883 | 4220000 | 0.4199 | 0.2102 | 0.0085 | 0.0004 | 0.0216 | 0.0036 | 0.0385 | 0.0085 | 0.0745 | 0.0222 | 0.1137 | 0.0287 | 0.1476 | 0.0534 | 0.2149 | 0.0825 | 0.2097 | 0.1756 | 0.1711 | 0.6250 | 0.0052 | 0.0000 | 0.0124 | 0.0018 | 0.0204 | 0.0040 | 0.0261 | 0.0141 | 0.0461 | 0.0196 | 0.0518 | 0.0236 | 0.0969 | 0.0460 | 0.1330 | 0.0873 | 0.6081 | 0.8036 | 0.0279 | 0.0590 | 0.0540 | 0.0729 | 0.0714 | 0.0521 | 0.0976 | 0.0486 | 0.1063 | 0.0972 | 0.0871 | 0.1632 | 0.1080 | 0.1042 | 0.1307 | 0.1250 | 0.3171 | 0.2778 | 0.0127 | 0.0202 | 0.0254 | 0.0419 | 0.0538 | 0.0695 | 0.1046 | 0.1674 | 0.5045 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0174 | 10.89 | 4.353 | 0.3184 | 42.9 | 326.59 | 2675.72 | 23343.4 | 0.5105 | 0.1490 | 0.0093 | 0.0007 | 0.0467 | 0.0029 | 0.1332 | 0.0168 | 0.2261 | 0.0557 | 0.2649 | 0.1187 | 0.2015 | 0.1957 | 0.0932 | 0.2556 | 0.0225 | 0.2405 | 0.0026 | 0.1134 | 0.0005 | 0.0000 | 0.0014 | 0.0005 | 0.0117 | 0.0029 | 0.0395 | 0.0124 | 0.0975 | 0.0337 | 0.1985 | 0.0723 | 0.2678 | 0.1849 | 0.2578 | 0.3562 | 0.1253 | 0.3371 | 0.1026 | 0.2983 | 0.2437 | 0.3365 | 0.2794 | 0.2278 | 0.2269 | 0.0988 | 0.1028 | 0.0292 | 0.0369 | 0.0090 | 0.0071 | 0.0004 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0196 | 0.0575 | 0.1217 | 0.1919 | 0.2514 | 0.2092 | 0.1174 | 0.0298 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 145 | 220 | | 5756 | 11661 | 118.5 | 36.39 | 167.20 | 124.25 | 81 | 90 | 98 | 104 | 111 | 118 | 128 | 143 | 165 | 0.0846 | 986 | 0.856 | 102.96 | 27.00 | 1 | 0.0480 | 276 | 0.0023 | 23.04 | 6.430 | 0.2521 | 15367.1 | 2200000 | 352000000 | 62600000000 | 0.4200 | 0.2279 | 0.0020 | 0.0000 | 0.0029 | 0.0002 | 0.0150 | 0.0010 | 0.0444 | 0.0056 | 0.1120 | 0.0292 | 0.1639 | 0.0606 | 0.1681 | 0.0606 | 0.2099 | 0.0964 | 0.2818 | 0.7463 | 0.0014 | 0.0000 | 0.0009 | 0.0000 | 0.0050 | 0.0007 | 0.0159 | 0.0020 | 0.0515 | 0.0182 | 0.0735 | 0.0309 | 0.0871 | 0.0309 | 0.1288 | 0.0545 | 0.6358 | 0.8628 | 0.0043 | 0.0018 | 0.0130 | 0.0107 | 0.0260 | 0.0178 | 0.0582 | 0.0516 | 0.1094 | 0.1335 | 0.1432 | 0.2046 | 0.1102 | 0.1174 | 0.1363 | 0.1459 | 0.3993 | 0.3167 | 0.0030 | 0.0057 | 0.0174 | 0.0449 | 0.0858 | 0.1233 | 0.1054 | 0.1337 | 0.4808 | 25 | 50 | 81 | 110 | 144 | 177 | 218 | 274 | 343 | 0.0021 | 46.18 | 7.043 | 0.2601 | 43391.7 | 14100000 | 5330000000 | 2240000000000 | 0.5309 | 0.1392 | 0.0066 | 0.0007 | 0.0509 | 0.0066 | 0.1329 | 0.0201 | 0.1554 | 0.0531 | 0.1718 | 0.1357 | 0.1718 | 0.1713 | 0.1337 | 0.1501 | 0.1001 | 0.1692 | 0.0766 | 0.2933 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0047 | 0.0031 | 0.0146 | 0.0122 | 0.0480 | 0.0427 | 0.0812 | 0.0603 | 0.0796 | 0.0606 | 0.1017 | 0.0883 | 0.6681 | 0.7316 | 0.0018 | 0.0022 | 0.0028 | 0.0073 | 0.0117 | 0.0105 | 0.0273 | 0.0350 | 0.0734 | 0.0815 | 0.1175 | 0.1238 | 0.0948 | 0.0986 | 0.1233 | 0.1371 | 0.5474 | 0.5040 | 0.0018 | 0.0034 | 0.0086 | 0.0243 | 0.0633 | 0.0955 | 0.0865 | 0.1196 | 0.5971 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1046 | 281 | | 697 | 6737 | 49.7 | 11.06 | 107.38 | 98.61 | 35 | 40 | 43 | 46 | 49 | 53 | 56 | 60 | 66 | 0.0687 | 463 | 0.653 | 94.02 | 20.03 | 1 | 0.3989 | 278 | 0.0147 | 2.37 | 4.400 | 0.5020 | 2589.0 | 140960 | 7970000 | 466000000 | 0.3646 | 0.2679 | 0.0024 | 0.0000 | 0.0049 | 0.0000 | 0.0147 | 0.0015 | 0.0293 | 0.0122 | 0.0880 | 0.0518 | 0.1174 | 0.0487 | 0.1418 | 0.0700 | 0.2103 | 0.1035 | 0.3912 | 0.7123 | 0.0018 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0179 | 0.0088 | 0.0448 | 0.0423 | 0.0448 | 0.0350 | 0.0538 | 0.0482 | 0.0878 | 0.0496 | 0.7437 | 0.8161 | 0.0000 | 0.0714 | 0.0067 | 0.0714 | 0.0537 | 0.1071 | 0.0604 | 0.2143 | 0.0940 | 0.1429 | 0.0872 | 0.1429 | 0.0940 | 0.2500 | 0.1678 | 0.0000 | 0.4362 | 0.0000 | 0.0000 | 0.0087 | 0.0029 | 0.0320 | 0.0552 | 0.0698 | 0.0756 | 0.1105 | 0.6453 | 16 | 26 | 41 | 57 | 78 | 101 | 132 | 173 | 239 | 0.0142 | 10.47 | 5.299 | 0.4760 | 21253.2 | 5970000 | 2090000000 | 847000000000 | 0.5145 | 0.1485 | 0.0252 | 0.0015 | 0.0572 | 0.0053 | 0.1725 | 0.0393 | 0.1812 | 0.0766 | 0.1764 | 0.1392 | 0.1764 | 0.1702 | 0.1066 | 0.1387 | 0.0640 | 0.1528 | 0.0407 | 0.2764 | 0.0006 | 0.0003 | 0.0013 | 0.0016 | 0.0064 | 0.0045 | 0.0186 | 0.0143 | 0.0578 | 0.0428 | 0.0902 | 0.0659 | 0.0876 | 0.0653 | 0.1139 | 0.0900 | 0.6236 | 0.7153 | 0.0010 | 0.0023 | 0.0048 | 0.0053 | 0.0120 | 0.0164 | 0.0307 | 0.0282 | 0.0801 | 0.0921 | 0.1243 | 0.1268 | 0.0998 | 0.1009 | 0.1166 | 0.1291 | 0.5307 | 0.4988 | 0.0004 | 0.0020 | 0.0086 | 0.0207 | 0.0718 | 0.1128 | 0.0910 | 0.1175 | 0.5752 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1239 | 302 | | 2914 | 11468 | 89.0 | 23.47 | 185.84 | 181.95 | 62 | 70 | 76 | 82 | 86 | 92 | 98 | 105 | 117 | 0.0557 | 639 | 1.081 | 95.21 | 32.02 | 1 | 0.0824 | 240 | 0.0040 | 15.08 | 5.828 | 0.3126 | 8469.4 | 866721 | 96000000 | 11600000000 | 0.4610 | 0.1943 | 0.0023 | 0.0000 | 0.0046 | 0.0011 | 0.0200 | 0.0027 | 0.0372 | 0.0057 | 0.0910 | 0.0289 | 0.1390 | 0.0427 | 0.1653 | 0.0632 | 0.2105 | 0.0967 | 0.3301 | 0.7589 | 0.0009 | 0.0000 | 0.0013 | 0.0004 | 0.0071 | 0.0000 | 0.0106 | 0.0014 | 0.0468 | 0.0195 | 0.0693 | 0.0287 | 0.0803 | 0.0337 | 0.1112 | 0.0553 | 0.6727 | 0.8611 | 0.0173 | 0.0000 | 0.0135 | 0.0406 | 0.0308 | 0.0508 | 0.0963 | 0.1015 | 0.1638 | 0.1929 | 0.1503 | 0.1675 | 0.1233 | 0.1168 | 0.1561 | 0.1269 | 0.2486 | 0.2030 | 0.0007 | 0.0045 | 0.0164 | 0.0425 | 0.0970 | 0.1231 | 0.1351 | 0.1552 | 0.4254 | 18 | 23 | 38 | 72 | 122 | 186 | 260 | 345 | 454 | 0.0125 | 51.50 | 6.479 | 0.3282 | 67639.0 | 31600000 | 17100000000 | 10300000000000 | 0.5344 | 0.1560 | 0.0634 | 0.0020 | 0.2146 | 0.0083 | 0.2992 | 0.1102 | 0.1675 | 0.1972 | 0.0951 | 0.2102 | 0.0764 | 0.1783 | 0.0472 | 0.1063 | 0.0187 | 0.0960 | 0.0179 | 0.0917 | 0.0002 | 0.0000 | 0.0004 | 0.0007 | 0.0031 | 0.0017 | 0.0183 | 0.0137 | 0.0645 | 0.0576 | 0.1169 | 0.1040 | 0.0833 | 0.0705 | 0.1163 | 0.1042 | 0.5970 | 0.6476 | 0.0010 | 0.0015 | 0.0027 | 0.0029 | 0.0067 | 0.0102 | 0.0284 | 0.0344 | 0.0832 | 0.0857 | 0.1256 | 0.1409 | 0.0964 | 0.1038 | 0.1348 | 0.1269 | 0.5211 | 0.4937 | 0.0009 | 0.0022 | 0.0037 | 0.0224 | 0.0757 | 0.1246 | 0.0944 | 0.1173 | 0.5588 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 146 | 51 | | 354 | 2232 | 83.5 | 10.81 | 232.77 | 142.92 | 70 | 73 | 77 | 80 | 83 | 86 | 89 | 94 | 99 | 0.1223 | 273 | 1.033 | 88.84 | 22.85 | 0 | 0.5791 | 205 | 0.0101 | 9.66 | 4.753 | 0.3349 | 7088.7 | 611712 | 53600000 | 4780000000 | 0.4194 | 0.1966 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0130 | 0.0028 | 0.0357 | 0.0085 | 0.0779 | 0.0397 | 0.1331 | 0.1473 | 0.1331 | 0.0368 | 0.2110 | 0.0822 | 0.3929 | 0.6827 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0030 | 0.0028 | 0.0178 | 0.0056 | 0.0562 | 0.0424 | 0.1124 | 0.1441 | 0.0621 | 0.0339 | 0.1213 | 0.0763 | 0.6243 | 0.6949 | 0.0000 | 1.0000 | 0.1000 | 0.0000 | 0.3667 | 0.0000 | 0.1000 | 0.0000 | 0.1667 | 0.0000 | 0.1333 | 0.0000 | 0.0667 | 0.0000 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0430 | 0.0699 | 0.1505 | 0.1720 | 0.1290 | 0.1559 | 0.2688 | 68 | 106 | 142 | 176 | 210 | 248 | 292 | 342 | 423 | 0.0013 | 85.74 | 6.901 | 0.1836 | 74597.8 | 29500000 | 13700000000 | 7190000000000 | 0.4379 | 0.1909 | 0.0169 | 0.0028 | 0.0639 | 0.0075 | 0.1899 | 0.0197 | 0.2199 | 0.0563 | 0.1748 | 0.1315 | 0.1485 | 0.1840 | 0.0846 | 0.1897 | 0.0639 | 0.1615 | 0.0376 | 0.2469 | 0.0008 | 0.0013 | 0.0016 | 0.0019 | 0.0055 | 0.0044 | 0.0181 | 0.0120 | 0.0604 | 0.0405 | 0.1319 | 0.0790 | 0.0981 | 0.0765 | 0.1389 | 0.0967 | 0.5447 | 0.6877 | 0.0013 | 0.0039 | 0.0054 | 0.0135 | 0.0148 | 0.0271 | 0.0620 | 0.0832 | 0.1334 | 0.1605 | 0.1536 | 0.1741 | 0.1361 | 0.1586 | 0.1860 | 0.1470 | 0.3073 | 0.2321 | 0.0000 | 0.0020 | 0.0121 | 0.0302 | 0.1099 | 0.1532 | 0.1149 | 0.1734 | 0.4042 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 771 | 729 | | 699 | 8074 | 51.0 | 15.12 | 134.99 | 188.23 | 31 | 35 | 40 | 45 | 50 | 56 | 62 | 67 | 72 | 0.0588 | 475 | 1.025 | 40.01 | 10.20 | 1 | 0.1373 | 96 | 0.0059 | 6.82 | 5.319 | 0.3605 | 2826.1 | 167621 | 10500000 | 678000000 | 0.3593 | 0.2671 | 0.0074 | 0.0000 | 0.0223 | 0.0106 | 0.0186 | 0.0195 | 0.0483 | 0.0283 | 0.1264 | 0.0496 | 0.1561 | 0.0637 | 0.1822 | 0.0991 | 0.2119 | 0.1558 | 0.2268 | 0.5735 | 0.0000 | 0.0000 | 0.0021 | 0.0016 | 0.0021 | 0.0094 | 0.0125 | 0.0141 | 0.0480 | 0.0297 | 0.0438 | 0.0375 | 0.0438 | 0.0531 | 0.0710 | 0.0688 | 0.7766 | 0.7859 | 0.0000 | 0.0267 | 0.0095 | 0.0533 | 0.0095 | 0.0533 | 0.0714 | 0.1867 | 0.0571 | 0.1333 | 0.0857 | 0.2000 | 0.1333 | 0.1733 | 0.1762 | 0.1467 | 0.4571 | 0.0267 | 0.0000 | 0.0029 | 0.0086 | 0.0201 | 0.0430 | 0.0630 | 0.0516 | 0.0860 | 0.7249 | 17 | 20 | 22 | 27 | 42 | 69 | 121 | 231 | 414 | 0.1036 | 10.05 | 4.238 | 0.6273 | 53649.5 | 30800000 | 20700000000 | 15500000000000 | 0.6068 | 0.0942 | 0.0493 | 0.0037 | 0.1637 | 0.0266 | 0.2249 | 0.1322 | 0.1657 | 0.1506 | 0.1400 | 0.1304 | 0.1183 | 0.1680 | 0.0552 | 0.1074 | 0.0414 | 0.0973 | 0.0414 | 0.1837 | 0.0004 | 0.0007 | 0.0012 | 0.0013 | 0.0046 | 0.0030 | 0.0150 | 0.0167 | 0.0547 | 0.0407 | 0.0875 | 0.0781 | 0.0586 | 0.0524 | 0.0848 | 0.0851 | 0.6933 | 0.7219 | 0.0005 | 0.0005 | 0.0019 | 0.0042 | 0.0043 | 0.0100 | 0.0168 | 0.0173 | 0.0570 | 0.0614 | 0.1049 | 0.0992 | 0.0608 | 0.0719 | 0.0967 | 0.1028 | 0.6571 | 0.6327 | 0.0000 | 0.0039 | 0.0035 | 0.0195 | 0.0500 | 0.0925 | 0.0626 | 0.0947 | 0.6733 |