High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 593 | 809 | | 9054 | 36760 | 386.6 | 78.38 | 181.80 | 168.48 | 283 | 319 | 345 | 368 | 389 | 408 | 428 | 453 | 485 | 0.0343 | 1261 | 1.172 | 117.32 | 46.07 | 2 | 0.0357 | 323 | 0.0013 | 28.99 | 6.930 | 0.2068 | 155613.0 | 64900000 | 28000000000 | 12400000000000 | 0.4514 | 0.1993 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0031 | 0.0000 | 0.0122 | 0.0006 | 0.0609 | 0.0126 | 0.1366 | 0.0323 | 0.1416 | 0.0335 | 0.1674 | 0.0533 | 0.4776 | 0.8677 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0025 | 0.0000 | 0.0256 | 0.0110 | 0.0577 | 0.0252 | 0.0556 | 0.0184 | 0.0717 | 0.0277 | 0.7858 | 0.9178 | 0.0076 | 0.0205 | 0.0124 | 0.1231 | 0.0275 | 0.0923 | 0.0927 | 0.1282 | 0.1683 | 0.1692 | 0.1999 | 0.1538 | 0.1484 | 0.0974 | 0.1374 | 0.1077 | 0.2060 | 0.1077 | 0.0006 | 0.0009 | 0.0039 | 0.0214 | 0.0744 | 0.1309 | 0.1084 | 0.1493 | 0.5102 | 20 | 40 | 70 | 101 | 134 | 175 | 226 | 293 | 410 | 0.0090 | 24.30 | 6.122 | 0.3733 | 61436.3 | 29700000 | 18600000000 | 14600000000000 | 0.4309 | 0.1918 | 0.0224 | 0.0007 | 0.1034 | 0.0058 | 0.2259 | 0.0487 | 0.1796 | 0.0900 | 0.1556 | 0.1611 | 0.1385 | 0.1955 | 0.0838 | 0.1496 | 0.0540 | 0.1427 | 0.0368 | 0.2058 | 0.0002 | 0.0003 | 0.0014 | 0.0006 | 0.0040 | 0.0027 | 0.0165 | 0.0104 | 0.0562 | 0.0443 | 0.1108 | 0.0905 | 0.0855 | 0.0719 | 0.1171 | 0.1021 | 0.6083 | 0.6773 | 0.0012 | 0.0016 | 0.0027 | 0.0043 | 0.0087 | 0.0124 | 0.0274 | 0.0393 | 0.0838 | 0.0961 | 0.1402 | 0.1499 | 0.1102 | 0.1133 | 0.1381 | 0.1378 | 0.4877 | 0.4453 | 0.0006 | 0.0015 | 0.0052 | 0.0174 | 0.0731 | 0.1259 | 0.1003 | 0.1286 | 0.5475 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1153 | 647 | | 7001 | 25505 | 556.6 | 122.04 | 346.05 | 471.05 | 401 | 439 | 476 | 515 | 554 | 594 | 633 | 670 | 719 | 0.0502 | 1281 | 1.091 | 94.40 | 31.32 | 2 | 0.0330 | 231 | 0.0008 | 49.47 | 7.389 | 0.1879 | 324688.0 | 198000000 | 125000000000 | 81200000000000 | 0.4396 | 0.2100 | 0.0007 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0002 | 0.0176 | 0.0008 | 0.0856 | 0.0167 | 0.1397 | 0.0345 | 0.1231 | 0.0336 | 0.1667 | 0.0500 | 0.4597 | 0.8643 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0003 | 0.0329 | 0.0127 | 0.0559 | 0.0246 | 0.0475 | 0.0180 | 0.0714 | 0.0252 | 0.7845 | 0.9193 | 0.0042 | 0.0190 | 0.0042 | 0.0521 | 0.0140 | 0.0474 | 0.0524 | 0.1232 | 0.1054 | 0.1943 | 0.1795 | 0.1848 | 0.1194 | 0.1327 | 0.1522 | 0.1137 | 0.3687 | 0.1327 | 0.0000 | 0.0026 | 0.0017 | 0.0185 | 0.0503 | 0.0888 | 0.0772 | 0.0943 | 0.6665 | 16 | 30 | 58 | 98 | 145 | 207 | 334 | 573 | 1040 | 0.0125 | 72.60 | 6.612 | 0.3697 | 341631.0 | 484000000 | 806000000000 | 1.47E+15 | 0.3657 | 0.3010 | 0.0271 | 0.0034 | 0.1024 | 0.0083 | 0.1982 | 0.0464 | 0.1992 | 0.1091 | 0.1937 | 0.1605 | 0.1274 | 0.2005 | 0.0763 | 0.1440 | 0.0457 | 0.1451 | 0.0301 | 0.1828 | 0.0006 | 0.0011 | 0.0022 | 0.0019 | 0.0049 | 0.0048 | 0.0175 | 0.0174 | 0.0458 | 0.0451 | 0.0736 | 0.0727 | 0.0584 | 0.0567 | 0.0751 | 0.0729 | 0.7219 | 0.7275 | 0.0005 | 0.0012 | 0.0032 | 0.0039 | 0.0065 | 0.0072 | 0.0159 | 0.0166 | 0.0490 | 0.0479 | 0.0772 | 0.0773 | 0.0599 | 0.0636 | 0.0830 | 0.0742 | 0.7047 | 0.7080 | 0.0005 | 0.0031 | 0.0048 | 0.0174 | 0.0468 | 0.0729 | 0.0592 | 0.0760 | 0.7193 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 577 | 529 | | 6874 | 21430 | 274.4 | 54.77 | 116.67 | 134.04 | 206 | 226 | 242 | 256 | 270 | 284 | 301 | 322 | 348 | 0.0497 | 1066 | 0.952 | 129.08 | 32.53 | 1 | 0.0428 | 294 | 0.0008 | 54.60 | 7.392 | 0.1620 | 78288.9 | 23200000 | 7120000000 | 2260000000000 | 0.4124 | 0.2339 | 0.0007 | 0.0000 | 0.0004 | 0.0000 | 0.0024 | 0.0002 | 0.0146 | 0.0009 | 0.0620 | 0.0167 | 0.1265 | 0.0357 | 0.1468 | 0.0339 | 0.1774 | 0.0560 | 0.4691 | 0.8567 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0052 | 0.0007 | 0.0245 | 0.0114 | 0.0505 | 0.0239 | 0.0545 | 0.0147 | 0.0759 | 0.0202 | 0.7879 | 0.9290 | 0.0068 | 0.0346 | 0.0101 | 0.0260 | 0.0245 | 0.1126 | 0.0785 | 0.1472 | 0.1647 | 0.2338 | 0.1976 | 0.1515 | 0.1309 | 0.1126 | 0.1512 | 0.1169 | 0.2356 | 0.0649 | 0.0012 | 0.0000 | 0.0080 | 0.0316 | 0.0807 | 0.1133 | 0.1072 | 0.1308 | 0.5272 | 10 | 13 | 16 | 28 | 55 | 99 | 154 | 222 | 315 | 0.0595 | 13.88 | 5.027 | 0.5286 | 31578.4 | 11600000 | 5190000000 | 2690000000000 | 0.5015 | 0.1536 | 0.0506 | 0.0016 | 0.2117 | 0.0180 | 0.3416 | 0.0886 | 0.1686 | 0.1769 | 0.1002 | 0.2501 | 0.0717 | 0.1846 | 0.0372 | 0.1200 | 0.0151 | 0.0904 | 0.0032 | 0.0698 | 0.0001 | 0.0000 | 0.0006 | 0.0005 | 0.0015 | 0.0008 | 0.0076 | 0.0083 | 0.0547 | 0.0435 | 0.0986 | 0.0770 | 0.0711 | 0.0601 | 0.1113 | 0.0927 | 0.6546 | 0.7171 | 0.0003 | 0.0007 | 0.0017 | 0.0016 | 0.0030 | 0.0034 | 0.0156 | 0.0219 | 0.0765 | 0.0905 | 0.1334 | 0.1420 | 0.0961 | 0.1062 | 0.1363 | 0.1430 | 0.5370 | 0.4906 | 0.0003 | 0.0010 | 0.0023 | 0.0117 | 0.0625 | 0.1168 | 0.0835 | 0.1295 | 0.5924 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1093 | 541 | | 6510 | 19083 | 329.3 | 67.71 | 96.25 | 108.79 | 246 | 270 | 288 | 306 | 322 | 340 | 362 | 390 | 424 | 0.0512 | 978 | 1.154 | 97.62 | 37.11 | 1 | 0.0393 | 256 | 0.0013 | 28.44 | 6.892 | 0.2102 | 112993.0 | 40300000 | 14900000000 | 5720000000000 | 0.4415 | 0.2097 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0043 | 0.0003 | 0.0149 | 0.0014 | 0.0652 | 0.0158 | 0.1269 | 0.0341 | 0.1409 | 0.0340 | 0.1777 | 0.0597 | 0.4684 | 0.8547 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0000 | 0.0065 | 0.0002 | 0.0277 | 0.0116 | 0.0554 | 0.0212 | 0.0606 | 0.0158 | 0.0862 | 0.0306 | 0.7611 | 0.9207 | 0.0042 | 0.0157 | 0.0067 | 0.0000 | 0.0177 | 0.0627 | 0.0725 | 0.1412 | 0.1197 | 0.1961 | 0.1594 | 0.1843 | 0.1197 | 0.1451 | 0.1476 | 0.1451 | 0.3524 | 0.1098 | 0.0013 | 0.0033 | 0.0086 | 0.0309 | 0.0800 | 0.1165 | 0.1009 | 0.1201 | 0.5385 | 7 | 9 | 12 | 27 | 55 | 86 | 127 | 179 | 256 | 0.0642 | 12.35 | 5.075 | 0.5282 | 21099.1 | 6350000 | 2360000000 | 1030000000000 | 0.4788 | 0.1572 | 0.0140 | 0.0020 | 0.0726 | 0.0070 | 0.1767 | 0.0276 | 0.1707 | 0.0700 | 0.1712 | 0.1521 | 0.1612 | 0.1785 | 0.0996 | 0.1459 | 0.0776 | 0.1537 | 0.0566 | 0.2631 | 0.0004 | 0.0001 | 0.0007 | 0.0005 | 0.0036 | 0.0013 | 0.0080 | 0.0073 | 0.0353 | 0.0283 | 0.0641 | 0.0499 | 0.0529 | 0.0434 | 0.0741 | 0.0687 | 0.7611 | 0.8004 | 0.0005 | 0.0002 | 0.0015 | 0.0007 | 0.0028 | 0.0046 | 0.0118 | 0.0137 | 0.0486 | 0.0587 | 0.0819 | 0.0869 | 0.0679 | 0.0845 | 0.1039 | 0.1128 | 0.6810 | 0.6378 | 0.0004 | 0.0006 | 0.0017 | 0.0103 | 0.0404 | 0.0685 | 0.0604 | 0.0855 | 0.7323 | ||
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1250 | 480 | | 6010 | 16284 | 271.9 | 68.74 | 353.07 | 523.57 | 175 | 224 | 245 | 264 | 279 | 293 | 309 | 328 | 354 | 0.0591 | 962 | 1.159 | 131.22 | 44.78 | 2 | 0.0542 | 326 | 0.0013 | 30.49 | 7.001 | 0.2258 | 78643.6 | 23800000 | 7440000000 | 2400000000000 | 0.4018 | 0.2328 | 0.0008 | 0.0000 | 0.0022 | 0.0004 | 0.0030 | 0.0013 | 0.0170 | 0.0019 | 0.0460 | 0.0171 | 0.0930 | 0.0344 | 0.1038 | 0.0340 | 0.1408 | 0.0511 | 0.5934 | 0.8598 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0002 | 0.0005 | 0.0026 | 0.0011 | 0.0142 | 0.0116 | 0.0318 | 0.0207 | 0.0259 | 0.0136 | 0.0451 | 0.0223 | 0.8798 | 0.9300 | 0.0040 | 0.0119 | 0.0161 | 0.0357 | 0.0185 | 0.0238 | 0.0611 | 0.1111 | 0.0957 | 0.1905 | 0.1262 | 0.1905 | 0.1294 | 0.1349 | 0.1455 | 0.1706 | 0.4035 | 0.1310 | 0.0006 | 0.0009 | 0.0061 | 0.0148 | 0.0439 | 0.0742 | 0.0805 | 0.1147 | 0.6642 | 9 | 12 | 15 | 20 | 33 | 124 | 394 | 769 | 1226 | 0.0716 | 108.75 | 5.493 | 0.4880 | 398768.0 | 556000000 | 859000000000 | 1.42E+15 | 0.4180 | 0.2363 | 0.0593 | 0.0007 | 0.2062 | 0.0235 | 0.3032 | 0.1478 | 0.1442 | 0.1457 | 0.1078 | 0.1974 | 0.0876 | 0.1807 | 0.0499 | 0.1175 | 0.0337 | 0.0960 | 0.0081 | 0.0907 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0016 | 0.0009 | 0.0066 | 0.0043 | 0.0421 | 0.0372 | 0.0706 | 0.0656 | 0.0492 | 0.0439 | 0.0706 | 0.0630 | 0.7590 | 0.7848 | 0.0002 | 0.0002 | 0.0019 | 0.0018 | 0.0028 | 0.0030 | 0.0118 | 0.0149 | 0.0476 | 0.0557 | 0.0800 | 0.0896 | 0.0607 | 0.0667 | 0.0891 | 0.0875 | 0.7059 | 0.6807 | 0.0004 | 0.0010 | 0.0028 | 0.0079 | 0.0436 | 0.0772 | 0.0515 | 0.0798 | 0.7360 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1164 | 748 | | 6717 | 22463 | 231.2 | 47.47 | 136.57 | 200.73 | 173 | 191 | 204 | 215 | 227 | 239 | 252 | 268 | 296 | 0.0526 | 1181 | 0.934 | 159.62 | 41.01 | 1 | 0.0582 | 391 | 0.0009 | 55.53 | 7.264 | 0.1600 | 55703.1 | 14000000 | 3650000000 | 990000000000 | 0.4604 | 0.1920 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0003 | 0.0127 | 0.0008 | 0.0689 | 0.0184 | 0.1261 | 0.0348 | 0.1510 | 0.0342 | 0.1834 | 0.0606 | 0.4552 | 0.8508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0001 | 0.0050 | 0.0003 | 0.0314 | 0.0132 | 0.0557 | 0.0204 | 0.0683 | 0.0150 | 0.0944 | 0.0288 | 0.7437 | 0.9222 | 0.0094 | 0.0220 | 0.0122 | 0.0293 | 0.0300 | 0.0549 | 0.0880 | 0.1172 | 0.1451 | 0.2125 | 0.1751 | 0.1978 | 0.1170 | 0.1026 | 0.1517 | 0.1172 | 0.2715 | 0.1465 | 0.0006 | 0.0029 | 0.0095 | 0.0350 | 0.1008 | 0.1316 | 0.1272 | 0.1459 | 0.4464 | 8 | 10 | 11 | 13 | 17 | 50 | 153 | 289 | 440 | 0.1678 | 32.49 | 4.522 | 0.5734 | 58941.1 | 34500000 | 24900000000 | 22000000000000 | 0.4912 | 0.1551 | 0.1222 | 0.0039 | 0.3163 | 0.0380 | 0.3182 | 0.2866 | 0.1251 | 0.2349 | 0.0660 | 0.1696 | 0.0394 | 0.1194 | 0.0089 | 0.0653 | 0.0039 | 0.0443 | 0.0000 | 0.0380 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0001 | 0.0002 | 0.0044 | 0.0063 | 0.0495 | 0.0387 | 0.0788 | 0.0683 | 0.0580 | 0.0512 | 0.1014 | 0.0836 | 0.7073 | 0.7515 | 0.0000 | 0.0003 | 0.0003 | 0.0005 | 0.0002 | 0.0016 | 0.0104 | 0.0097 | 0.0555 | 0.0675 | 0.1057 | 0.1099 | 0.0760 | 0.0890 | 0.1243 | 0.1280 | 0.6276 | 0.5934 | 0.0000 | 0.0006 | 0.0006 | 0.0083 | 0.0528 | 0.0884 | 0.0720 | 0.1141 | 0.6632 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 959 | 713 | | 6139 | 10848 | 256.2 | 53.54 | 207.18 | 194.13 | 190 | 210 | 225 | 238 | 252 | 266 | 283 | 302 | 326 | 0.0678 | 736 | 1.177 | 102.18 | 37.66 | 1 | 0.0415 | 255 | 0.0008 | 47.93 | 7.299 | 0.1591 | 68517.0 | 19100000 | 5540000000 | 1670000000000 | 0.4834 | 0.1799 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0032 | 0.0003 | 0.0156 | 0.0014 | 0.0740 | 0.0133 | 0.1454 | 0.0377 | 0.1504 | 0.0343 | 0.1835 | 0.0591 | 0.4267 | 0.8538 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0016 | 0.0002 | 0.0059 | 0.0012 | 0.0355 | 0.0092 | 0.0646 | 0.0250 | 0.0616 | 0.0171 | 0.0826 | 0.0290 | 0.7478 | 0.9183 | 0.0067 | 0.0235 | 0.0114 | 0.0141 | 0.0352 | 0.0469 | 0.0856 | 0.1643 | 0.1369 | 0.1925 | 0.1835 | 0.2207 | 0.1274 | 0.0845 | 0.1340 | 0.0986 | 0.2795 | 0.1549 | 0.0024 | 0.0041 | 0.0093 | 0.0368 | 0.0764 | 0.1195 | 0.1012 | 0.1326 | 0.5176 | 19 | 34 | 61 | 103 | 155 | 210 | 274 | 353 | 472 | 0.0078 | 34.55 | 6.449 | 0.3311 | 80606.7 | 42400000 | 27300000000 | 20400000000000 | 0.4122 | 0.2269 | 0.0375 | 0.0010 | 0.1827 | 0.0076 | 0.2438 | 0.0851 | 0.1774 | 0.1506 | 0.1360 | 0.1962 | 0.1064 | 0.2035 | 0.0572 | 0.1157 | 0.0420 | 0.0994 | 0.0171 | 0.1407 | 0.0008 | 0.0002 | 0.0010 | 0.0012 | 0.0031 | 0.0027 | 0.0179 | 0.0119 | 0.0702 | 0.0586 | 0.1159 | 0.1040 | 0.0844 | 0.0695 | 0.1125 | 0.0949 | 0.5943 | 0.6571 | 0.0016 | 0.0020 | 0.0038 | 0.0020 | 0.0071 | 0.0076 | 0.0245 | 0.0311 | 0.0919 | 0.0967 | 0.1321 | 0.1652 | 0.1025 | 0.1119 | 0.1394 | 0.1317 | 0.4971 | 0.4518 | 0.0016 | 0.0016 | 0.0043 | 0.0200 | 0.0832 | 0.1402 | 0.0836 | 0.1216 | 0.5440 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 659 | 414 | | 3454 | 6251 | 174.4 | 39.87 | 242.89 | 154.32 | 131 | 143 | 152 | 159 | 167 | 177 | 189 | 204 | 226 | 0.1125 | 703 | 1.107 | 91.24 | 26.63 | 1 | 0.0617 | 213 | 0.0019 | 25.62 | 6.561 | 0.2385 | 32018.5 | 6210000 | 1280000000 | 278000000000 | 0.4520 | 0.2052 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0088 | 0.0006 | 0.0206 | 0.0022 | 0.0697 | 0.0235 | 0.1434 | 0.0423 | 0.1298 | 0.0346 | 0.1684 | 0.0676 | 0.4579 | 0.8289 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0003 | 0.0052 | 0.0003 | 0.0351 | 0.0160 | 0.0762 | 0.0274 | 0.0616 | 0.0189 | 0.1043 | 0.0335 | 0.7155 | 0.9036 | 0.0017 | 0.0154 | 0.0134 | 0.0205 | 0.0185 | 0.0308 | 0.0487 | 0.1026 | 0.1546 | 0.1231 | 0.1748 | 0.1846 | 0.1294 | 0.1538 | 0.1429 | 0.0923 | 0.3160 | 0.2769 | 0.0007 | 0.0033 | 0.0080 | 0.0361 | 0.0916 | 0.1424 | 0.0989 | 0.1404 | 0.4786 | 79 | 111 | 142 | 170 | 206 | 251 | 299 | 360 | 457 | 0.0013 | 68.96 | 7.135 | 0.2323 | 82803.2 | 35900000 | 18500000000 | 10900000000000 | 0.5283 | 0.1292 | 0.0088 | 0.0007 | 0.0739 | 0.0045 | 0.1684 | 0.0182 | 0.1611 | 0.0636 | 0.1859 | 0.1374 | 0.1720 | 0.2049 | 0.1061 | 0.1528 | 0.0820 | 0.1545 | 0.0417 | 0.2633 | 0.0003 | 0.0002 | 0.0027 | 0.0005 | 0.0066 | 0.0040 | 0.0217 | 0.0160 | 0.0714 | 0.0488 | 0.1042 | 0.0905 | 0.0819 | 0.0726 | 0.1153 | 0.1014 | 0.5959 | 0.6660 | 0.0041 | 0.0042 | 0.0051 | 0.0035 | 0.0128 | 0.0229 | 0.0389 | 0.0660 | 0.1064 | 0.1313 | 0.1529 | 0.1771 | 0.1233 | 0.1188 | 0.1483 | 0.1465 | 0.4082 | 0.3299 | 0.0004 | 0.0031 | 0.0100 | 0.0268 | 0.0824 | 0.1234 | 0.1031 | 0.1388 | 0.5121 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1178 | 149 | | 2587 | 12832 | 62.1 | 10.66 | 74.22 | 169.03 | 47 | 54 | 57 | 60 | 63 | 65 | 68 | 71 | 75 | 0.0646 | 829 | 0.944 | 80.06 | 19.03 | 2 | 0.0723 | 187 | 0.0369 | 1.29 | 3.638 | 0.6360 | 3969.1 | 260301 | 17500000 | 1200000000 | 0.4305 | 0.2137 | 0.0020 | 0.0000 | 0.0020 | 0.0004 | 0.0055 | 0.0008 | 0.0201 | 0.0075 | 0.0472 | 0.0210 | 0.0693 | 0.0334 | 0.0844 | 0.0346 | 0.1920 | 0.0516 | 0.5774 | 0.8507 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0079 | 0.0059 | 0.0238 | 0.0192 | 0.0331 | 0.0298 | 0.0348 | 0.0271 | 0.0591 | 0.0365 | 0.8386 | 0.8811 | 0.0719 | 0.0968 | 0.1079 | 0.1290 | 0.0755 | 0.1935 | 0.1151 | 0.0968 | 0.1043 | 0.1613 | 0.1187 | 0.1613 | 0.1475 | 0.0968 | 0.0827 | 0.0645 | 0.1763 | 0.0000 | 0.0036 | 0.0107 | 0.0220 | 0.0377 | 0.0519 | 0.0732 | 0.1087 | 0.1741 | 0.5181 | 15 | 19 | 23 | 28 | 32 | 38 | 43 | 50 | 94 | 0.1646 | 3.32 | 2.652 | 0.8090 | 34078.2 | 30400000 | 31700000000 | 35800000000000 | 0.6942 | 0.0754 | 0.1033 | 0.0274 | 0.0813 | 0.0364 | 0.0769 | 0.0502 | 0.0769 | 0.0707 | 0.1319 | 0.1021 | 0.1275 | 0.1360 | 0.1319 | 0.1585 | 0.1275 | 0.1667 | 0.1429 | 0.2520 | 0.0237 | 0.0180 | 0.0188 | 0.0239 | 0.0094 | 0.0319 | 0.0066 | 0.0430 | 0.0248 | 0.0663 | 0.0370 | 0.0857 | 0.0304 | 0.1021 | 0.0679 | 0.1201 | 0.7815 | 0.5089 | 0.0044 | 0.0017 | 0.0044 | 0.0035 | 0.0074 | 0.0095 | 0.0118 | 0.0173 | 0.0376 | 0.0528 | 0.0516 | 0.0692 | 0.0553 | 0.0614 | 0.1061 | 0.0882 | 0.7214 | 0.6964 | 0.0006 | 0.0038 | 0.0038 | 0.0101 | 0.0258 | 0.0396 | 0.0491 | 0.0931 | 0.7742 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 477 | 250 | | 5842 | 6724 | 472.6 | 109.57 | 64.97 | 82.36 | 352 | 384 | 409 | 431 | 454 | 480 | 513 | 551 | 621 | 0.1120 | 753 | 1.059 | 127.44 | 46.01 | 1 | 0.0580 | 339 | 0.0010 | 46.76 | 7.191 | 0.1916 | 235384.0 | 124000000 | 68700000000 | 40200000000000 | 0.4185 | 0.2273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0000 | 0.0183 | 0.0015 | 0.0595 | 0.0197 | 0.1231 | 0.0436 | 0.1215 | 0.0347 | 0.1414 | 0.0528 | 0.5311 | 0.8478 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0061 | 0.0000 | 0.0303 | 0.0139 | 0.0654 | 0.0255 | 0.0629 | 0.0177 | 0.0794 | 0.0279 | 0.7550 | 0.9150 | 0.0020 | 0.0082 | 0.0049 | 0.0109 | 0.0225 | 0.0136 | 0.0470 | 0.0625 | 0.1136 | 0.1223 | 0.1185 | 0.1929 | 0.0803 | 0.0870 | 0.1156 | 0.1304 | 0.4956 | 0.3723 | 0.0012 | 0.0040 | 0.0064 | 0.0302 | 0.0770 | 0.1132 | 0.0870 | 0.1140 | 0.5671 | 5 | 7 | 9 | 13 | 27 | 45 | 76 | 118 | 187 | 0.0898 | 5.57 | 4.185 | 0.6123 | 11003.2 | 2590000 | 720000000 | 223000000000 | 0.5988 | 0.0846 | 0.0147 | 0.0063 | 0.0939 | 0.0135 | 0.2413 | 0.0387 | 0.1971 | 0.0729 | 0.1823 | 0.1674 | 0.1050 | 0.2115 | 0.0958 | 0.1476 | 0.0405 | 0.1611 | 0.0295 | 0.1809 | 0.0004 | 0.0025 | 0.0000 | 0.0011 | 0.0016 | 0.0035 | 0.0130 | 0.0074 | 0.0438 | 0.0337 | 0.0686 | 0.0561 | 0.0603 | 0.0459 | 0.0832 | 0.0775 | 0.7292 | 0.7724 | 0.0000 | 0.0000 | 0.0015 | 0.0046 | 0.0040 | 0.0040 | 0.0206 | 0.0259 | 0.0667 | 0.0856 | 0.1003 | 0.1086 | 0.0832 | 0.0851 | 0.1169 | 0.1132 | 0.6068 | 0.5730 | 0.0000 | 0.0000 | 0.0044 | 0.0146 | 0.0521 | 0.0838 | 0.0710 | 0.1094 | 0.6648 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 459 | 658 | | 11362 | 20851 | 286.6 | 57.22 | 160.43 | 166.77 | 216 | 238 | 254 | 268 | 283 | 297 | 315 | 335 | 362 | 0.0609 | 1269 | 1.250 | 84.58 | 36.89 | 1 | 0.0202 | 229 | 0.0006 | 69.33 | 7.619 | 0.1453 | 85435.4 | 26400000 | 8470000000 | 2810000000000 | 0.3998 | 0.2496 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0026 | 0.0000 | 0.0151 | 0.0008 | 0.0564 | 0.0119 | 0.1324 | 0.0353 | 0.1449 | 0.0348 | 0.1680 | 0.0534 | 0.4798 | 0.8638 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0000 | 0.0057 | 0.0004 | 0.0244 | 0.0088 | 0.0561 | 0.0236 | 0.0596 | 0.0148 | 0.0768 | 0.0231 | 0.7756 | 0.9293 | 0.0061 | 0.0143 | 0.0094 | 0.0544 | 0.0304 | 0.0716 | 0.0839 | 0.1777 | 0.1733 | 0.2521 | 0.1926 | 0.1519 | 0.1291 | 0.0917 | 0.1512 | 0.0974 | 0.2241 | 0.0888 | 0.0015 | 0.0022 | 0.0078 | 0.0347 | 0.0806 | 0.1342 | 0.1129 | 0.1362 | 0.4899 | 14 | 18 | 28 | 51 | 95 | 156 | 222 | 299 | 405 | 0.0196 | 36.84 | 6.010 | 0.3723 | 53550.1 | 23300000 | 11800000000 | 6650000000000 | 0.5064 | 0.1481 | 0.0625 | 0.0012 | 0.2600 | 0.0157 | 0.3022 | 0.1503 | 0.1409 | 0.1993 | 0.0988 | 0.2074 | 0.0736 | 0.1703 | 0.0334 | 0.0942 | 0.0252 | 0.0818 | 0.0034 | 0.0799 | 0.0001 | 0.0000 | 0.0004 | 0.0005 | 0.0019 | 0.0015 | 0.0115 | 0.0099 | 0.0600 | 0.0532 | 0.1157 | 0.0968 | 0.0747 | 0.0636 | 0.1141 | 0.0984 | 0.6214 | 0.6761 | 0.0004 | 0.0010 | 0.0028 | 0.0037 | 0.0065 | 0.0110 | 0.0223 | 0.0260 | 0.0761 | 0.0864 | 0.1468 | 0.1528 | 0.0956 | 0.1004 | 0.1209 | 0.1293 | 0.5286 | 0.4895 | 0.0000 | 0.0010 | 0.0039 | 0.0157 | 0.0717 | 0.1279 | 0.0896 | 0.1188 | 0.5713 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 438 | 338 | | 5309 | 17377 | 254.0 | 51.30 | 154.44 | 205.30 | 192 | 208 | 222 | 236 | 250 | 263 | 278 | 296 | 323 | 0.0642 | 1116 | 0.650 | 145.45 | 37.54 | 1 | 0.0868 | 461 | 0.0009 | 54.07 | 7.276 | 0.1615 | 67165.6 | 18500000 | 5270000000 | 1560000000000 | 0.4223 | 0.2163 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0065 | 0.0004 | 0.0185 | 0.0008 | 0.0648 | 0.0167 | 0.1339 | 0.0415 | 0.1444 | 0.0348 | 0.1632 | 0.0518 | 0.4682 | 0.8540 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0000 | 0.0094 | 0.0004 | 0.0315 | 0.0125 | 0.0602 | 0.0262 | 0.0616 | 0.0142 | 0.0778 | 0.0232 | 0.7567 | 0.9236 | 0.0092 | 0.0185 | 0.0150 | 0.0139 | 0.0242 | 0.0509 | 0.0715 | 0.1667 | 0.1349 | 0.1944 | 0.1915 | 0.1944 | 0.1165 | 0.0972 | 0.1442 | 0.1065 | 0.2930 | 0.1574 | 0.0016 | 0.0032 | 0.0068 | 0.0275 | 0.0749 | 0.1247 | 0.1064 | 0.1466 | 0.5084 | 13 | 15 | 18 | 23 | 36 | 81 | 184 | 315 | 474 | 0.0496 | 33.73 | 5.257 | 0.4918 | 65995.6 | 37600000 | 25100000000 | 18900000000000 | 0.5553 | 0.1158 | 0.0613 | 0.0005 | 0.2441 | 0.0274 | 0.3613 | 0.1747 | 0.1129 | 0.1642 | 0.0914 | 0.2211 | 0.0581 | 0.1832 | 0.0280 | 0.0932 | 0.0258 | 0.0658 | 0.0172 | 0.0700 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0008 | 0.0007 | 0.0082 | 0.0069 | 0.0483 | 0.0458 | 0.0858 | 0.0729 | 0.0508 | 0.0451 | 0.0837 | 0.0765 | 0.7219 | 0.7519 | 0.0002 | 0.0000 | 0.0004 | 0.0004 | 0.0008 | 0.0017 | 0.0152 | 0.0196 | 0.0552 | 0.0582 | 0.1050 | 0.1163 | 0.0616 | 0.0694 | 0.0952 | 0.0936 | 0.6664 | 0.6407 | 0.0000 | 0.0007 | 0.0011 | 0.0112 | 0.0520 | 0.0947 | 0.0605 | 0.0867 | 0.6931 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 936 | 824 | | 6449 | 21481 | 423.4 | 94.11 | 65.04 | 80.19 | 317 | 342 | 363 | 384 | 406 | 430 | 462 | 503 | 558 | 0.0487 | 1047 | 0.994 | 112.45 | 43.42 | 1 | 0.0482 | 311 | 0.0009 | 45.87 | 7.285 | 0.1707 | 188113.0 | 87800000 | 42900000000 | 22000000000000 | 0.4226 | 0.2238 | 0.0002 | 0.0000 | 0.0005 | 0.0002 | 0.0027 | 0.0002 | 0.0178 | 0.0020 | 0.0677 | 0.0179 | 0.1322 | 0.0358 | 0.1404 | 0.0349 | 0.1777 | 0.0545 | 0.4607 | 0.8547 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0066 | 0.0000 | 0.0301 | 0.0114 | 0.0587 | 0.0202 | 0.0584 | 0.0129 | 0.0904 | 0.0227 | 0.7539 | 0.9328 | 0.0032 | 0.0026 | 0.0097 | 0.0129 | 0.0130 | 0.0206 | 0.0536 | 0.0851 | 0.1218 | 0.2010 | 0.1404 | 0.1469 | 0.1055 | 0.1392 | 0.1502 | 0.1624 | 0.4026 | 0.2294 | 0.0011 | 0.0054 | 0.0058 | 0.0307 | 0.0719 | 0.1135 | 0.0973 | 0.1135 | 0.5607 | 6 | 8 | 10 | 14 | 26 | 50 | 85 | 121 | 172 | 0.0959 | 7.90 | 4.467 | 0.5774 | 10661.1 | 2560000 | 795000000 | 304000000000 | 0.4718 | 0.1706 | 0.0377 | 0.0018 | 0.1636 | 0.0076 | 0.2796 | 0.0566 | 0.1975 | 0.1401 | 0.1494 | 0.2175 | 0.0821 | 0.2166 | 0.0488 | 0.1351 | 0.0309 | 0.1061 | 0.0105 | 0.1187 | 0.0006 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0077 | 0.0074 | 0.0426 | 0.0363 | 0.0686 | 0.0582 | 0.0524 | 0.0451 | 0.0781 | 0.0670 | 0.7499 | 0.7845 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0019 | 0.0030 | 0.0108 | 0.0165 | 0.0583 | 0.0629 | 0.0853 | 0.0985 | 0.0701 | 0.0795 | 0.1004 | 0.1112 | 0.6732 | 0.6271 | 0.0000 | 0.0001 | 0.0014 | 0.0094 | 0.0487 | 0.0799 | 0.0555 | 0.0843 | 0.7206 | ||
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 609 | 251 | | 8474 | 32235 | 492.3 | 132.68 | 164.80 | 304.29 | 304 | 403 | 447 | 478 | 505 | 531 | 562 | 596 | 642 | 0.0423 | 1362 | 0.553 | 103.04 | 22.02 | 6 | 0.0340 | 288 | 0.0004 | 114.84 | 8.011 | 0.1304 | 259967.0 | 144000000 | 83000000000 | 49400000000000 | 0.3722 | 0.2591 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0037 | 0.0003 | 0.0143 | 0.0023 | 0.0499 | 0.0166 | 0.1100 | 0.0376 | 0.1112 | 0.0351 | 0.1452 | 0.0452 | 0.5648 | 0.8630 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0001 | 0.0025 | 0.0009 | 0.0146 | 0.0117 | 0.0325 | 0.0201 | 0.0307 | 0.0127 | 0.0470 | 0.0181 | 0.8723 | 0.9363 | 0.0022 | 0.0048 | 0.0077 | 0.0143 | 0.0132 | 0.0286 | 0.0548 | 0.0835 | 0.1064 | 0.2124 | 0.1656 | 0.1742 | 0.1162 | 0.1074 | 0.1436 | 0.1480 | 0.3904 | 0.2267 | 0.0004 | 0.0024 | 0.0034 | 0.0209 | 0.0482 | 0.0869 | 0.0897 | 0.1054 | 0.6428 | 11 | 14 | 16 | 19 | 25 | 41 | 97 | 243 | 543 | 0.1744 | 25.68 | 4.127 | 0.6433 | 119746.0 | 132000000 | 179000000000 | 274000000000000 | 0.3012 | 0.3397 | 0.0899 | 0.0040 | 0.2395 | 0.0218 | 0.2653 | 0.1374 | 0.1444 | 0.1732 | 0.1091 | 0.1910 | 0.0818 | 0.1739 | 0.0413 | 0.1102 | 0.0177 | 0.0848 | 0.0111 | 0.1039 | 0.0005 | 0.0004 | 0.0016 | 0.0005 | 0.0018 | 0.0022 | 0.0158 | 0.0127 | 0.0501 | 0.0477 | 0.0704 | 0.0633 | 0.0461 | 0.0432 | 0.0696 | 0.0655 | 0.7443 | 0.7646 | 0.0003 | 0.0003 | 0.0003 | 0.0026 | 0.0043 | 0.0048 | 0.0182 | 0.0201 | 0.0595 | 0.0574 | 0.0778 | 0.0868 | 0.0553 | 0.0575 | 0.0768 | 0.0805 | 0.7076 | 0.6901 | 0.0004 | 0.0001 | 0.0031 | 0.0149 | 0.0534 | 0.0785 | 0.0435 | 0.0762 | 0.7299 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 735 | 634 | | 3383 | 13602 | 420.5 | 93.73 | 24.16 | 65.07 | 310 | 345 | 369 | 393 | 413 | 435 | 458 | 483 | 531 | 0.0471 | 641 | 0.708 | 187.75 | 42.58 | 1 | 0.1469 | 497 | 0.0008 | 81.64 | 7.362 | 0.1445 | 185607.0 | 86200000 | 42200000000 | 21900000000000 | 0.4414 | 0.2109 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0190 | 0.0000 | 0.0557 | 0.0201 | 0.1348 | 0.0447 | 0.1232 | 0.0352 | 0.1517 | 0.0569 | 0.5108 | 0.8430 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0000 | 0.0327 | 0.0138 | 0.0779 | 0.0312 | 0.0610 | 0.0204 | 0.0832 | 0.0309 | 0.7391 | 0.9038 | 0.0169 | 0.0000 | 0.0127 | 0.0252 | 0.0465 | 0.0377 | 0.0465 | 0.0755 | 0.1269 | 0.1447 | 0.1882 | 0.1698 | 0.0867 | 0.1195 | 0.1501 | 0.1069 | 0.3256 | 0.3208 | 0.0000 | 0.0050 | 0.0126 | 0.0320 | 0.0961 | 0.1420 | 0.1030 | 0.1470 | 0.4623 | 5 | 6 | 7 | 7 | 9 | 10 | 13 | 19 | 43 | 0.1856 | 1.96 | 2.069 | 0.6343 | 4817.1 | 2540000 | 1750000000 | 1330000000000 | 0.5397 | 0.1164 | 0.0580 | 0.0279 | 0.1116 | 0.0343 | 0.1949 | 0.0594 | 0.2024 | 0.1054 | 0.1741 | 0.1577 | 0.1310 | 0.1758 | 0.0759 | 0.1589 | 0.0387 | 0.1368 | 0.0134 | 0.1438 | 0.0052 | 0.0139 | 0.0041 | 0.0154 | 0.0067 | 0.0198 | 0.0191 | 0.0302 | 0.0479 | 0.0395 | 0.0621 | 0.0552 | 0.0592 | 0.0599 | 0.0943 | 0.0738 | 0.7012 | 0.6922 | 0.0010 | 0.0012 | 0.0035 | 0.0035 | 0.0045 | 0.0104 | 0.0205 | 0.0267 | 0.0730 | 0.0818 | 0.0985 | 0.1021 | 0.0725 | 0.0754 | 0.1151 | 0.1155 | 0.6113 | 0.5833 | 0.0026 | 0.0039 | 0.0039 | 0.0176 | 0.0511 | 0.0815 | 0.0686 | 0.1047 | 0.6662 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 441 | 854 | | 1964 | 2153 | 94.0 | 19.07 | 5.89 | 2.19 | 65 | 75 | 84 | 91 | 97 | 103 | 107 | 111 | 116 | 0.2216 | 477 | 0.494 | 340.58 | 73.33 | 1 | 0.5046 | 991 | 0.0224 | 1.75 | 4.105 | 0.5669 | 9205.0 | 931383 | 96800000 | 10300000000 | 0.4309 | 0.2010 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0147 | 0.0005 | 0.0359 | 0.0058 | 0.0661 | 0.0242 | 0.1184 | 0.0453 | 0.1380 | 0.0353 | 0.1959 | 0.0679 | 0.4237 | 0.8211 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0013 | 0.0005 | 0.0109 | 0.0052 | 0.0300 | 0.0235 | 0.0504 | 0.0434 | 0.0549 | 0.0314 | 0.0709 | 0.0581 | 0.7797 | 0.8378 | 0.0235 | 0.0909 | 0.0293 | 0.0000 | 0.0704 | 0.1818 | 0.1056 | 0.0909 | 0.1144 | 0.3636 | 0.1525 | 0.2727 | 0.1290 | 0.0000 | 0.1290 | 0.0000 | 0.2463 | 0.0000 | 0.0000 | 0.0027 | 0.0045 | 0.0163 | 0.0506 | 0.0624 | 0.0678 | 0.0850 | 0.7107 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5417 | 0.29 | 0.926 | 0.8524 | 39.5 | 290.243 | 2305.17 | 19573.6 | 0.5333 | 0.1268 | 0.0126 | 0.0006 | 0.0816 | 0.0054 | 0.1641 | 0.0320 | 0.2592 | 0.0633 | 0.2505 | 0.1333 | 0.1534 | 0.1960 | 0.0621 | 0.2340 | 0.0155 | 0.2117 | 0.0010 | 0.1236 | 0.0000 | 0.0000 | 0.0139 | 0.0011 | 0.0357 | 0.0096 | 0.1130 | 0.0340 | 0.1897 | 0.0919 | 0.2161 | 0.1338 | 0.2254 | 0.1875 | 0.1586 | 0.2953 | 0.0476 | 0.2469 | 0.1946 | 0.4222 | 0.2754 | 0.2667 | 0.2402 | 0.1378 | 0.1718 | 0.1244 | 0.0787 | 0.0400 | 0.0311 | 0.0089 | 0.0062 | 0.0000 | 0.0021 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0552 | 0.1027 | 0.1986 | 0.2182 | 0.1910 | 0.1171 | 0.0849 | 0.0246 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1056 | 260 | | 4207 | 15495 | 500.5 | 108.07 | 87.49 | 106.42 | 370 | 405 | 433 | 464 | 493 | 520 | 549 | 587 | 643 | 0.0565 | 876 | 0.989 | 119.87 | 30.61 | 1 | 0.0661 | 278 | 0.0007 | 62.59 | 7.399 | 0.1476 | 262186.0 | 144000000 | 82200000000 | 49100000000000 | 0.4288 | 0.2109 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0003 | 0.0164 | 0.0020 | 0.0574 | 0.0191 | 0.1257 | 0.0417 | 0.1374 | 0.0355 | 0.1640 | 0.0528 | 0.4940 | 0.8486 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0015 | 0.0000 | 0.0073 | 0.0012 | 0.0297 | 0.0144 | 0.0559 | 0.0271 | 0.0612 | 0.0163 | 0.0749 | 0.0302 | 0.7681 | 0.9108 | 0.0029 | 0.0000 | 0.0086 | 0.0052 | 0.0187 | 0.0363 | 0.0691 | 0.0777 | 0.1281 | 0.2280 | 0.1727 | 0.1969 | 0.0964 | 0.0829 | 0.1410 | 0.1451 | 0.3626 | 0.2280 | 0.0015 | 0.0035 | 0.0035 | 0.0266 | 0.0693 | 0.1151 | 0.0925 | 0.1231 | 0.5648 | 8 | 11 | 16 | 26 | 43 | 64 | 98 | 150 | 246 | 0.0352 | 15.63 | 5.119 | 0.5277 | 18978.6 | 5860000 | 2150000000 | 885000000000 | 0.5211 | 0.1359 | 0.0214 | 0.0046 | 0.0878 | 0.0160 | 0.1521 | 0.0567 | 0.1383 | 0.0743 | 0.1784 | 0.1350 | 0.1508 | 0.1607 | 0.1196 | 0.1350 | 0.0920 | 0.1405 | 0.0595 | 0.2771 | 0.0007 | 0.0012 | 0.0020 | 0.0016 | 0.0043 | 0.0040 | 0.0126 | 0.0130 | 0.0415 | 0.0366 | 0.0643 | 0.0582 | 0.0519 | 0.0478 | 0.0821 | 0.0687 | 0.7407 | 0.7690 | 0.0005 | 0.0003 | 0.0002 | 0.0013 | 0.0029 | 0.0039 | 0.0170 | 0.0181 | 0.0503 | 0.0629 | 0.0867 | 0.0982 | 0.0697 | 0.0732 | 0.0965 | 0.1166 | 0.6762 | 0.6256 | 0.0004 | 0.0016 | 0.0036 | 0.0126 | 0.0506 | 0.0725 | 0.0620 | 0.0889 | 0.7079 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 582 | 250 | | 4778 | 14966 | 457.7 | 96.53 | 89.22 | 140.57 | 342 | 375 | 399 | 423 | 446 | 472 | 503 | 544 | 595 | 0.0565 | 845 | 1.104 | 103.97 | 26.91 | 1 | 0.0479 | 229 | 0.0010 | 47.20 | 7.130 | 0.1892 | 218847.0 | 109000000 | 56500000000 | 30300000000000 | 0.4000 | 0.2511 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0045 | 0.0004 | 0.0175 | 0.0009 | 0.0684 | 0.0206 | 0.1267 | 0.0402 | 0.1305 | 0.0356 | 0.1626 | 0.0566 | 0.4879 | 0.8457 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0048 | 0.0004 | 0.0342 | 0.0151 | 0.0585 | 0.0274 | 0.0650 | 0.0193 | 0.0849 | 0.0278 | 0.7521 | 0.9101 | 0.0078 | 0.0314 | 0.0045 | 0.0314 | 0.0201 | 0.0419 | 0.0536 | 0.0576 | 0.1095 | 0.2042 | 0.1430 | 0.1937 | 0.1128 | 0.1152 | 0.1296 | 0.1571 | 0.4190 | 0.1675 | 0.0018 | 0.0041 | 0.0115 | 0.0290 | 0.0809 | 0.1241 | 0.0938 | 0.1159 | 0.5389 | 5 | 7 | 8 | 10 | 12 | 21 | 71 | 181 | 309 | 0.1594 | 14.47 | 4.050 | 0.6108 | 27717.5 | 11400000 | 5320000000 | 2730000000000 | 0.4192 | 0.2070 | 0.0600 | 0.0054 | 0.1989 | 0.0109 | 0.2420 | 0.0827 | 0.1839 | 0.1544 | 0.1407 | 0.2452 | 0.0882 | 0.1962 | 0.0563 | 0.0990 | 0.0169 | 0.0990 | 0.0131 | 0.1072 | 0.0002 | 0.0002 | 0.0007 | 0.0002 | 0.0009 | 0.0008 | 0.0083 | 0.0087 | 0.0333 | 0.0322 | 0.0492 | 0.0453 | 0.0395 | 0.0316 | 0.0572 | 0.0465 | 0.8108 | 0.8345 | 0.0000 | 0.0005 | 0.0018 | 0.0005 | 0.0025 | 0.0013 | 0.0079 | 0.0070 | 0.0370 | 0.0436 | 0.0631 | 0.0662 | 0.0484 | 0.0554 | 0.0667 | 0.0759 | 0.7725 | 0.7495 | 0.0000 | 0.0000 | 0.0019 | 0.0086 | 0.0378 | 0.0557 | 0.0431 | 0.0633 | 0.7896 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 212 | 744 | | 6614 | 10325 | 163.1 | 32.35 | 119.28 | 84.78 | 125 | 138 | 147 | 155 | 161 | 167 | 175 | 185 | 203 | 0.0792 | 818 | 1.172 | 127.35 | 40.25 | 1 | 0.0452 | 299 | 0.0020 | 27.70 | 6.559 | 0.2300 | 27650.6 | 4880000 | 902000000 | 175000000000 | 0.4500 | 0.2031 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0033 | 0.0005 | 0.0157 | 0.0009 | 0.0518 | 0.0158 | 0.1045 | 0.0311 | 0.1239 | 0.0356 | 0.1680 | 0.0538 | 0.5318 | 0.8621 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0073 | 0.0005 | 0.0238 | 0.0110 | 0.0514 | 0.0224 | 0.0550 | 0.0146 | 0.0835 | 0.0286 | 0.7771 | 0.9229 | 0.0114 | 0.0090 | 0.0194 | 0.0495 | 0.0411 | 0.0495 | 0.1006 | 0.1802 | 0.1600 | 0.2117 | 0.1794 | 0.1757 | 0.1486 | 0.0991 | 0.1394 | 0.0991 | 0.2000 | 0.1261 | 0.0006 | 0.0063 | 0.0157 | 0.0466 | 0.0913 | 0.1326 | 0.1222 | 0.1698 | 0.4148 | 30 | 47 | 62 | 79 | 97 | 119 | 148 | 185 | 240 | 0.0026 | 32.10 | 6.579 | 0.2832 | 21415.5 | 4970000 | 1370000000 | 425000000000 | 0.5726 | 0.1051 | 0.0233 | 0.0012 | 0.1341 | 0.0059 | 0.2743 | 0.0446 | 0.1832 | 0.1006 | 0.1522 | 0.1877 | 0.1071 | 0.1954 | 0.0694 | 0.1475 | 0.0367 | 0.1460 | 0.0197 | 0.1709 | 0.0004 | 0.0005 | 0.0023 | 0.0009 | 0.0082 | 0.0027 | 0.0218 | 0.0148 | 0.0827 | 0.0624 | 0.1269 | 0.0968 | 0.1019 | 0.0859 | 0.1392 | 0.1237 | 0.5166 | 0.6124 | 0.0015 | 0.0023 | 0.0073 | 0.0051 | 0.0094 | 0.0167 | 0.0462 | 0.0607 | 0.1152 | 0.1293 | 0.1711 | 0.1795 | 0.1100 | 0.1215 | 0.1510 | 0.1484 | 0.3883 | 0.3364 | 0.0007 | 0.0041 | 0.0070 | 0.0374 | 0.0934 | 0.1539 | 0.1074 | 0.1421 | 0.4540 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 840 | 632 | | 7599 | 25331 | 439.9 | 83.79 | 168.72 | 276.45 | 340 | 369 | 390 | 410 | 429 | 450 | 476 | 508 | 555 | 0.0492 | 1247 | 1.002 | 122.50 | 43.46 | 1 | 0.0425 | 323 | 0.0006 | 77.97 | 7.638 | 0.1430 | 200554.0 | 94700000 | 46300000000 | 23400000000000 | 0.4550 | 0.1957 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0026 | 0.0000 | 0.0094 | 0.0007 | 0.0535 | 0.0144 | 0.1165 | 0.0319 | 0.1324 | 0.0357 | 0.1602 | 0.0471 | 0.5253 | 0.8703 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0278 | 0.0111 | 0.0578 | 0.0182 | 0.0625 | 0.0137 | 0.0881 | 0.0211 | 0.7604 | 0.9358 | 0.0025 | 0.0077 | 0.0101 | 0.0193 | 0.0126 | 0.0386 | 0.0666 | 0.2278 | 0.1265 | 0.2162 | 0.1678 | 0.2355 | 0.1273 | 0.1042 | 0.1669 | 0.0965 | 0.3196 | 0.0541 | 0.0012 | 0.0026 | 0.0096 | 0.0417 | 0.0858 | 0.1214 | 0.1033 | 0.1219 | 0.5125 | 6 | 7 | 9 | 11 | 16 | 45 | 143 | 328 | 583 | 0.1315 | 51.22 | 4.587 | 0.5228 | 104886.0 | 87500000 | 85800000000 | 94300000000000 | 0.5042 | 0.1314 | 0.1174 | 0.0045 | 0.3070 | 0.0508 | 0.2798 | 0.2324 | 0.1277 | 0.2165 | 0.1108 | 0.1884 | 0.0404 | 0.1303 | 0.0113 | 0.0944 | 0.0038 | 0.0477 | 0.0019 | 0.0350 | 0.0001 | 0.0001 | 0.0012 | 0.0004 | 0.0026 | 0.0011 | 0.0093 | 0.0084 | 0.0522 | 0.0465 | 0.0772 | 0.0740 | 0.0532 | 0.0513 | 0.0848 | 0.0734 | 0.7194 | 0.7448 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0021 | 0.0027 | 0.0093 | 0.0091 | 0.0560 | 0.0627 | 0.0918 | 0.1001 | 0.0656 | 0.0705 | 0.1066 | 0.1206 | 0.6678 | 0.6332 | 0.0003 | 0.0015 | 0.0032 | 0.0089 | 0.0529 | 0.0819 | 0.0600 | 0.0898 | 0.7015 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 306 | 790 | | 10808 | 25449 | 298.9 | 63.05 | 184.36 | 193.71 | 220 | 246 | 264 | 280 | 296 | 313 | 331 | 352 | 380 | 0.0474 | 1207 | 1.110 | 105.26 | 43.74 | 1 | 0.0265 | 286 | 0.0005 | 81.12 | 7.748 | 0.1366 | 93311.6 | 30300000 | 10200000000 | 3580000000000 | 0.4573 | 0.1982 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0004 | 0.0195 | 0.0011 | 0.0692 | 0.0138 | 0.1340 | 0.0324 | 0.1426 | 0.0358 | 0.1632 | 0.0476 | 0.4660 | 0.8689 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0002 | 0.0056 | 0.0003 | 0.0270 | 0.0101 | 0.0603 | 0.0229 | 0.0590 | 0.0172 | 0.0778 | 0.0237 | 0.7694 | 0.9257 | 0.0068 | 0.0176 | 0.0084 | 0.0352 | 0.0340 | 0.0557 | 0.0748 | 0.1701 | 0.1511 | 0.1935 | 0.1730 | 0.1437 | 0.1270 | 0.1114 | 0.1505 | 0.1202 | 0.2744 | 0.1525 | 0.0002 | 0.0013 | 0.0071 | 0.0283 | 0.0777 | 0.1375 | 0.1086 | 0.1338 | 0.5055 | 13 | 17 | 24 | 51 | 111 | 191 | 262 | 346 | 463 | 0.0242 | 36.87 | 6.001 | 0.4043 | 71512.1 | 35800000 | 20900000000 | 13700000000000 | 0.4160 | 0.2115 | 0.0758 | 0.0028 | 0.2291 | 0.0178 | 0.2929 | 0.1362 | 0.1723 | 0.1731 | 0.1102 | 0.2094 | 0.0642 | 0.1810 | 0.0336 | 0.1219 | 0.0141 | 0.0926 | 0.0079 | 0.0652 | 0.0001 | 0.0002 | 0.0002 | 0.0002 | 0.0011 | 0.0009 | 0.0083 | 0.0060 | 0.0510 | 0.0445 | 0.0925 | 0.0721 | 0.0732 | 0.0598 | 0.1091 | 0.0919 | 0.6645 | 0.7243 | 0.0003 | 0.0004 | 0.0012 | 0.0030 | 0.0038 | 0.0091 | 0.0196 | 0.0268 | 0.0753 | 0.0878 | 0.1241 | 0.1477 | 0.1070 | 0.1093 | 0.1439 | 0.1482 | 0.5247 | 0.4678 | 0.0002 | 0.0006 | 0.0017 | 0.0130 | 0.0634 | 0.1073 | 0.0854 | 0.1313 | 0.5971 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 916 | 208 | | 6312 | 22401 | 516.6 | 108.92 | 194.68 | 249.60 | 387 | 432 | 460 | 485 | 506 | 529 | 554 | 590 | 659 | 0.0487 | 1092 | 1.116 | 137.30 | 45.69 | 1 | 0.0535 | 338 | 0.0007 | 69.42 | 7.543 | 0.1440 | 278766.0 | 157000000 | 92800000000 | 57400000000000 | 0.4428 | 0.2109 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0016 | 0.0000 | 0.0104 | 0.0019 | 0.0576 | 0.0179 | 0.1165 | 0.0397 | 0.1247 | 0.0358 | 0.1680 | 0.0608 | 0.5208 | 0.8440 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0008 | 0.0320 | 0.0120 | 0.0592 | 0.0239 | 0.0665 | 0.0194 | 0.0912 | 0.0340 | 0.7446 | 0.9099 | 0.0077 | 0.0096 | 0.0132 | 0.0096 | 0.0252 | 0.0382 | 0.0614 | 0.0669 | 0.1107 | 0.1369 | 0.1590 | 0.2452 | 0.0998 | 0.1051 | 0.1239 | 0.1624 | 0.3991 | 0.2261 | 0.0021 | 0.0045 | 0.0156 | 0.0403 | 0.0904 | 0.1255 | 0.1172 | 0.1321 | 0.4722 | 8 | 11 | 15 | 29 | 79 | 153 | 245 | 373 | 559 | 0.0687 | 42.39 | 5.505 | 0.4513 | 100197.0 | 70500000 | 59900000000 | 58200000000000 | 0.4609 | 0.1681 | 0.0552 | 0.0013 | 0.1678 | 0.0137 | 0.2533 | 0.1058 | 0.1683 | 0.1355 | 0.1438 | 0.1985 | 0.1037 | 0.1961 | 0.0500 | 0.1334 | 0.0302 | 0.1063 | 0.0276 | 0.1095 | 0.0003 | 0.0001 | 0.0002 | 0.0003 | 0.0016 | 0.0011 | 0.0067 | 0.0064 | 0.0528 | 0.0424 | 0.0871 | 0.0742 | 0.0642 | 0.0559 | 0.0943 | 0.0845 | 0.6926 | 0.7352 | 0.0001 | 0.0002 | 0.0007 | 0.0008 | 0.0026 | 0.0047 | 0.0182 | 0.0210 | 0.0633 | 0.0712 | 0.1119 | 0.1303 | 0.0840 | 0.0811 | 0.1128 | 0.1143 | 0.6064 | 0.5764 | 0.0003 | 0.0010 | 0.0028 | 0.0120 | 0.0577 | 0.0977 | 0.0730 | 0.1042 | 0.6513 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |