High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 653 | 516 | | 909 | 892 | 22.8 | 11.51 | 5.20 | 1.87 | 10 | 12 | 15 | 18 | 21 | 23 | 27 | 31 | 38 | 0.3509 | 313 | 1.192 | 32.02 | 13.34 | 0 | 0.0957 | 87 | 0.0035 | 17.77 | 5.844 | 0.2797 | 651.5 | 22448.7 | 894003 | 39700000 | 0.3319 | 0.2816 | 0.0000 | 0.0019 | 0.0202 | 0.0000 | 0.0847 | 0.0133 | 0.0605 | 0.0475 | 0.1613 | 0.0665 | 0.2016 | 0.1141 | 0.1855 | 0.1255 | 0.1935 | 0.1464 | 0.0927 | 0.4848 | 0.0000 | 0.0015 | 0.0019 | 0.0000 | 0.0135 | 0.0073 | 0.0250 | 0.0219 | 0.0442 | 0.0335 | 0.0673 | 0.0510 | 0.0635 | 0.0496 | 0.0865 | 0.0700 | 0.6981 | 0.7653 | 0.0000 | 0.0063 | 0.0000 | 0.0063 | 0.0000 | 0.0313 | 0.0478 | 0.0750 | 0.0772 | 0.0938 | 0.1103 | 0.1313 | 0.0809 | 0.1125 | 0.0846 | 0.0875 | 0.5993 | 0.4563 | 0.0051 | 0.0077 | 0.0077 | 0.0281 | 0.0537 | 0.0793 | 0.0793 | 0.0997 | 0.6394 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0223 | 7.70 | 4.011 | 0.3535 | 30.5 | 195.177 | 1334.83 | 9619.86 | 0.5452 | 0.1074 | 0.0732 | 0.0034 | 0.1616 | 0.0358 | 0.2500 | 0.0903 | 0.2348 | 0.1652 | 0.1372 | 0.2129 | 0.1067 | 0.2215 | 0.0244 | 0.1567 | 0.0091 | 0.0716 | 0.0030 | 0.0426 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0377 | 0.0061 | 0.0934 | 0.0547 | 0.1506 | 0.1106 | 0.2218 | 0.1385 | 0.1869 | 0.1823 | 0.2050 | 0.2272 | 0.0976 | 0.2807 | 0.0334 | 0.1483 | 0.1517 | 0.3347 | 0.2699 | 0.3051 | 0.2416 | 0.1525 | 0.1645 | 0.0551 | 0.0848 | 0.0042 | 0.0437 | 0.0000 | 0.0103 | 0.0000 | 0.0000 | 0.0000 | 0.0071 | 0.0321 | 0.1214 | 0.1821 | 0.2304 | 0.2054 | 0.1232 | 0.0804 | 0.0179 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 553 | 850 | | 1687 | 2459 | 300.5 | 204.06 | 15.65 | 29.61 | 110 | 143 | 172 | 196 | 226 | 271 | 333 | 444 | 654 | 0.1684 | 414 | 0.726 | 89.00 | 15.23 | 2 | 0.1114 | 188 | 0.0012 | 52.86 | 6.939 | 0.2192 | 131887.0 | 75200000 | 49500000000 | 35300000000000 | 0.3308 | 0.2934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0059 | 0.0039 | 0.0676 | 0.0130 | 0.1618 | 0.0649 | 0.2176 | 0.1104 | 0.1294 | 0.0909 | 0.1147 | 0.1078 | 0.3029 | 0.6091 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0102 | 0.0089 | 0.0422 | 0.0337 | 0.0588 | 0.0452 | 0.0409 | 0.0425 | 0.0537 | 0.0558 | 0.7941 | 0.8113 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0045 | 0.0056 | 0.0543 | 0.0446 | 0.0860 | 0.0864 | 0.0294 | 0.0362 | 0.0633 | 0.0585 | 0.7579 | 0.7688 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0701 | 0.0484 | 0.0668 | 0.7613 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 13 | 16 | 0.6120 | 0.70 | 1.147 | 0.8761 | 1121.1 | 209476 | 49200000 | 12700000000 | 0.5069 | 0.1463 | 0.1731 | 0.0340 | 0.1621 | 0.0635 | 0.1264 | 0.1020 | 0.1978 | 0.1422 | 0.1264 | 0.1592 | 0.1209 | 0.1494 | 0.0604 | 0.1476 | 0.0275 | 0.1127 | 0.0055 | 0.0894 | 0.1136 | 0.0296 | 0.0971 | 0.0553 | 0.0531 | 0.0872 | 0.1081 | 0.1153 | 0.1117 | 0.1379 | 0.1026 | 0.1254 | 0.0861 | 0.1347 | 0.1081 | 0.1160 | 0.2198 | 0.1986 | 0.0110 | 0.0000 | 0.0385 | 0.0060 | 0.0055 | 0.0060 | 0.0220 | 0.0482 | 0.1154 | 0.1024 | 0.1264 | 0.1265 | 0.1154 | 0.1205 | 0.1209 | 0.1325 | 0.4451 | 0.4578 | 0.0618 | 0.0579 | 0.0734 | 0.0463 | 0.0888 | 0.1004 | 0.0811 | 0.1197 | 0.3707 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 374 | 827 | | 538 | 5755 | 91.8 | 48.44 | 171.54 | 297.95 | 29 | 40 | 57 | 74 | 89 | 101 | 116 | 140 | 161 | 0.0895 | 515 | 1.275 | 31.62 | 12.17 | 2 | 0.1543 | 83 | 0.0025 | 70.15 | 6.080 | 0.1560 | 10772.9 | 1460000 | 216000000 | 34000000000 | 0.3272 | 0.2735 | 0.0000 | 0.0000 | 0.0282 | 0.0000 | 0.1338 | 0.0000 | 0.1901 | 0.0198 | 0.1620 | 0.1581 | 0.1268 | 0.1937 | 0.1479 | 0.1621 | 0.1056 | 0.1581 | 0.1056 | 0.3083 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0031 | 0.0131 | 0.0800 | 0.0551 | 0.0985 | 0.0866 | 0.0431 | 0.0525 | 0.1138 | 0.0840 | 0.6585 | 0.7087 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0055 | 0.0000 | 0.0383 | 0.0156 | 0.1038 | 0.1328 | 0.1038 | 0.1016 | 0.1093 | 0.1016 | 0.1421 | 0.1328 | 0.4973 | 0.5000 | 0.0000 | 0.0000 | 0.0078 | 0.0389 | 0.0661 | 0.1128 | 0.0973 | 0.1128 | 0.5642 | 17 | 19 | 20 | 22 | 25 | 35 | 92 | 249 | 645 | 0.1812 | 27.53 | 3.742 | 0.6466 | 118185.0 | 112000000 | 119000000000 | 139000000000000 | 0.7250 | 0.0477 | 0.0600 | 0.0080 | 0.2240 | 0.0282 | 0.3600 | 0.1690 | 0.1600 | 0.1932 | 0.0920 | 0.2012 | 0.0480 | 0.1469 | 0.0240 | 0.1066 | 0.0240 | 0.0624 | 0.0080 | 0.0845 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0020 | 0.0012 | 0.0231 | 0.0168 | 0.0909 | 0.0895 | 0.1324 | 0.1111 | 0.0856 | 0.0847 | 0.1232 | 0.1219 | 0.5422 | 0.5742 | 0.0000 | 0.0000 | 0.0047 | 0.0060 | 0.0087 | 0.0146 | 0.0379 | 0.0368 | 0.0883 | 0.0856 | 0.1270 | 0.1336 | 0.1017 | 0.0967 | 0.1222 | 0.1182 | 0.5095 | 0.5086 | 0.0000 | 0.0000 | 0.0086 | 0.0281 | 0.0944 | 0.1354 | 0.0929 | 0.1218 | 0.5187 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 824 | 149 | | 3095 | 1375 | 156.7 | 47.45 | 110.15 | 90.82 | 105 | 115 | 124 | 134 | 145 | 160 | 176 | 196 | 227 | 0.3382 | 465 | 1.062 | 83.41 | 29.00 | 1 | 0.0666 | 206 | 0.0014 | 36.35 | 6.808 | 0.1956 | 26798.4 | 4990000 | 1010000000 | 217000000000 | 0.4010 | 0.2369 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0164 | 0.0004 | 0.0622 | 0.0073 | 0.1630 | 0.0383 | 0.2209 | 0.0865 | 0.1773 | 0.0930 | 0.1651 | 0.1290 | 0.1937 | 0.6455 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0066 | 0.0003 | 0.0164 | 0.0033 | 0.0564 | 0.0210 | 0.0986 | 0.0440 | 0.0737 | 0.0367 | 0.1015 | 0.0660 | 0.6458 | 0.8286 | 0.0014 | 0.0026 | 0.0014 | 0.0104 | 0.0096 | 0.0181 | 0.0493 | 0.0907 | 0.1315 | 0.1684 | 0.1685 | 0.1813 | 0.1055 | 0.1192 | 0.1425 | 0.1684 | 0.3904 | 0.2409 | 0.0008 | 0.0000 | 0.0046 | 0.0245 | 0.0772 | 0.1376 | 0.1009 | 0.1223 | 0.5321 | 23 | 34 | 49 | 66 | 79 | 101 | 130 | 181 | 247 | 0.0068 | 27.40 | 5.667 | 0.3730 | 20376.5 | 5090000 | 1510000000 | 502000000000 | 0.4253 | 0.1878 | 0.0226 | 0.0041 | 0.1584 | 0.0225 | 0.2443 | 0.0736 | 0.1493 | 0.0920 | 0.1946 | 0.2086 | 0.1584 | 0.2658 | 0.0588 | 0.1411 | 0.0136 | 0.1022 | 0.0000 | 0.0900 | 0.0000 | 0.0000 | 0.0112 | 0.0048 | 0.0128 | 0.0060 | 0.0400 | 0.0290 | 0.1808 | 0.1351 | 0.2208 | 0.2268 | 0.1120 | 0.1218 | 0.1408 | 0.1375 | 0.2816 | 0.3390 | 0.0050 | 0.0118 | 0.0099 | 0.0147 | 0.0347 | 0.0265 | 0.0743 | 0.0588 | 0.1535 | 0.1971 | 0.2153 | 0.1971 | 0.0990 | 0.1088 | 0.1361 | 0.1412 | 0.2723 | 0.2441 | 0.0039 | 0.0137 | 0.0333 | 0.0412 | 0.1902 | 0.2039 | 0.1000 | 0.1294 | 0.2843 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1221 | 489 | | 5050 | 9168 | 265.7 | 87.85 | 74.96 | 66.43 | 154 | 189 | 212 | 235 | 259 | 289 | 319 | 348 | 383 | 0.0929 | 852 | 1.188 | 99.54 | 33.29 | 1 | 0.0475 | 240 | 0.0005 | 91.15 | 7.822 | 0.1210 | 78333.9 | 25000000 | 8530000000 | 3070000000000 | 0.5037 | 0.1623 | 0.0005 | 0.0005 | 0.0015 | 0.0000 | 0.0109 | 0.0005 | 0.0583 | 0.0055 | 0.1635 | 0.0478 | 0.2362 | 0.1113 | 0.1517 | 0.0894 | 0.1507 | 0.1313 | 0.2268 | 0.6136 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0088 | 0.0024 | 0.0437 | 0.0269 | 0.0917 | 0.0623 | 0.0616 | 0.0423 | 0.0857 | 0.0657 | 0.7070 | 0.8003 | 0.0007 | 0.0031 | 0.0007 | 0.0031 | 0.0080 | 0.0263 | 0.0280 | 0.0789 | 0.0874 | 0.1316 | 0.1475 | 0.1579 | 0.0821 | 0.1300 | 0.1335 | 0.1409 | 0.5120 | 0.3282 | 0.0013 | 0.0021 | 0.0038 | 0.0158 | 0.0554 | 0.1046 | 0.0721 | 0.0900 | 0.6549 | 11 | 16 | 25 | 36 | 53 | 74 | 98 | 128 | 174 | 0.0129 | 12.77 | 5.601 | 0.4237 | 10031.5 | 1760000 | 357000000 | 80500000000 | 0.3984 | 0.2086 | 0.0229 | 0.0012 | 0.0980 | 0.0097 | 0.2408 | 0.0421 | 0.1943 | 0.1069 | 0.1845 | 0.1858 | 0.1176 | 0.1895 | 0.0686 | 0.1656 | 0.0424 | 0.1425 | 0.0310 | 0.1567 | 0.0002 | 0.0004 | 0.0007 | 0.0006 | 0.0047 | 0.0040 | 0.0163 | 0.0144 | 0.0503 | 0.0421 | 0.0822 | 0.0653 | 0.0726 | 0.0593 | 0.0966 | 0.0829 | 0.6764 | 0.7310 | 0.0010 | 0.0016 | 0.0042 | 0.0039 | 0.0065 | 0.0079 | 0.0293 | 0.0347 | 0.0700 | 0.0851 | 0.1059 | 0.1316 | 0.0958 | 0.1056 | 0.1322 | 0.1300 | 0.5550 | 0.4996 | 0.0003 | 0.0030 | 0.0082 | 0.0192 | 0.0604 | 0.0978 | 0.0835 | 0.1173 | 0.6102 | ||
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 870 | 152 | | 2506 | 5703 | 72.8 | 23.73 | 226.65 | 206.12 | 44 | 52 | 59 | 65 | 71 | 77 | 83 | 92 | 106 | 0.1012 | 577 | 0.226 | 301.04 | 33.94 | 3 | 0.4254 | 1066 | 0.0017 | 34.53 | 6.624 | 0.1875 | 5856.8 | 514772 | 48800000 | 4950000000 | 0.4100 | 0.2367 | 0.0000 | 0.0000 | 0.0094 | 0.0000 | 0.0309 | 0.0015 | 0.0738 | 0.0082 | 0.1639 | 0.0494 | 0.1966 | 0.0937 | 0.1949 | 0.1105 | 0.1768 | 0.1549 | 0.1536 | 0.5818 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0011 | 0.0009 | 0.0147 | 0.0035 | 0.0548 | 0.0288 | 0.0892 | 0.0399 | 0.0926 | 0.0465 | 0.1242 | 0.0798 | 0.6222 | 0.8005 | 0.0050 | 0.0068 | 0.0149 | 0.0068 | 0.0215 | 0.0375 | 0.0809 | 0.1024 | 0.1601 | 0.2321 | 0.1700 | 0.1945 | 0.1221 | 0.1229 | 0.1535 | 0.1468 | 0.2723 | 0.1502 | 0.0017 | 0.0025 | 0.0142 | 0.0418 | 0.0879 | 0.1431 | 0.1305 | 0.1423 | 0.4360 | 33 | 48 | 74 | 110 | 160 | 220 | 294 | 390 | 525 | 0.0110 | 30.01 | 5.917 | 0.3620 | 93846.7 | 52100000 | 34500000000 | 25800000000000 | 0.5031 | 0.1657 | 0.0592 | 0.0019 | 0.2513 | 0.0205 | 0.2592 | 0.1189 | 0.1526 | 0.1841 | 0.1079 | 0.1937 | 0.0921 | 0.1688 | 0.0434 | 0.1119 | 0.0224 | 0.0985 | 0.0118 | 0.1017 | 0.0000 | 0.0000 | 0.0023 | 0.0013 | 0.0080 | 0.0035 | 0.0221 | 0.0190 | 0.0865 | 0.0723 | 0.1319 | 0.1138 | 0.1021 | 0.0826 | 0.1444 | 0.1157 | 0.5027 | 0.5919 | 0.0011 | 0.0026 | 0.0038 | 0.0026 | 0.0145 | 0.0168 | 0.0376 | 0.0510 | 0.1175 | 0.1395 | 0.1760 | 0.1802 | 0.1180 | 0.1298 | 0.1352 | 0.1486 | 0.3965 | 0.3288 | 0.0009 | 0.0018 | 0.0086 | 0.0378 | 0.0991 | 0.1535 | 0.1153 | 0.1346 | 0.4484 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 323 | 867 | | 400 | 2994 | 116.9 | 58.63 | 22.33 | 36.51 | 37 | 54 | 72 | 93 | 117 | 142 | 160 | 180 | 198 | 0.1226 | 367 | 0.942 | 240.52 | 72.24 | 1 | 1.5125 | 605 | 0.0035 | 23.39 | 5.736 | 0.2403 | 17090.1 | 2810000 | 490000000 | 88800000000 | 0.2385 | 0.3935 | 0.0000 | 0.0000 | 0.0513 | 0.0000 | 0.1795 | 0.0000 | 0.1538 | 0.0058 | 0.1667 | 0.1503 | 0.3333 | 0.3006 | 0.0897 | 0.1214 | 0.0256 | 0.1676 | 0.0000 | 0.2543 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0126 | 0.0035 | 0.0544 | 0.0632 | 0.1088 | 0.0912 | 0.0502 | 0.0421 | 0.0711 | 0.0807 | 0.7029 | 0.7193 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0268 | 0.0745 | 0.0893 | 0.1491 | 0.1518 | 0.0497 | 0.0893 | 0.0745 | 0.0714 | 0.6398 | 0.5714 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0650 | 0.1250 | 0.0450 | 0.0850 | 0.6700 | 10 | 12 | 13 | 14 | 15 | 16 | 17 | 19 | 23 | 0.4250 | 1.44 | 1.571 | 0.8267 | 1831.5 | 395412 | 109000000 | 33000000000 | 0.4696 | 0.1619 | 0.1029 | 0.0135 | 0.1942 | 0.0486 | 0.2233 | 0.0774 | 0.1786 | 0.1014 | 0.1553 | 0.1463 | 0.0932 | 0.1635 | 0.0447 | 0.1825 | 0.0078 | 0.1530 | 0.0000 | 0.1137 | 0.0663 | 0.0119 | 0.1183 | 0.0404 | 0.1222 | 0.0652 | 0.0923 | 0.0836 | 0.1105 | 0.1218 | 0.0923 | 0.1358 | 0.0715 | 0.1547 | 0.0871 | 0.1574 | 0.2393 | 0.2291 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0236 | 0.0175 | 0.0669 | 0.0658 | 0.1024 | 0.1491 | 0.1614 | 0.1184 | 0.1024 | 0.1009 | 0.1102 | 0.1272 | 0.4331 | 0.4167 | 0.0845 | 0.0310 | 0.0338 | 0.0451 | 0.1070 | 0.1070 | 0.1014 | 0.0986 | 0.3915 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1251 | 214 | | 356 | 5823 | 35.2 | 7.41 | 113.18 | 175.08 | 27 | 29 | 30 | 32 | 34 | 37 | 39 | 42 | 46 | 0.0792 | 461 | 0.420 | 101.19 | 15.26 | 1 | 0.8736 | 311 | 0.0113 | 6.98 | 4.700 | 0.3318 | 1292.1 | 49511.8 | 1970000 | 81800000 | 0.4112 | 0.2070 | 0.0000 | 0.0000 | 0.0044 | 0.0000 | 0.0439 | 0.0000 | 0.0877 | 0.0118 | 0.1711 | 0.0708 | 0.1798 | 0.0678 | 0.2719 | 0.1121 | 0.1491 | 0.1563 | 0.0921 | 0.5811 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0000 | 0.0261 | 0.0113 | 0.0554 | 0.0592 | 0.0782 | 0.0563 | 0.1401 | 0.0676 | 0.1759 | 0.0901 | 0.5049 | 0.7155 | 0.0127 | 0.0625 | 0.0000 | 0.1250 | 0.0759 | 0.0625 | 0.2532 | 0.2500 | 0.1646 | 0.1250 | 0.1772 | 0.1875 | 0.1139 | 0.1250 | 0.1013 | 0.0625 | 0.1013 | 0.0000 | 0.0000 | 0.0242 | 0.0424 | 0.0667 | 0.1030 | 0.1576 | 0.1455 | 0.1636 | 0.2970 | 16 | 20 | 25 | 33 | 45 | 68 | 103 | 161 | 264 | 0.0724 | 6.00 | 4.044 | 0.6522 | 43457.4 | 30200000 | 26300000000 | 25200000000000 | 0.6089 | 0.0954 | 0.0138 | 0.0044 | 0.0881 | 0.0044 | 0.1796 | 0.0413 | 0.1503 | 0.0739 | 0.1658 | 0.1706 | 0.1330 | 0.1715 | 0.1278 | 0.1407 | 0.0950 | 0.1416 | 0.0466 | 0.2515 | 0.0000 | 0.0009 | 0.0015 | 0.0004 | 0.0041 | 0.0017 | 0.0164 | 0.0133 | 0.0590 | 0.0506 | 0.0878 | 0.0665 | 0.0678 | 0.0545 | 0.0965 | 0.0982 | 0.6668 | 0.7139 | 0.0015 | 0.0000 | 0.0015 | 0.0017 | 0.0037 | 0.0050 | 0.0161 | 0.0209 | 0.0701 | 0.0771 | 0.1103 | 0.1131 | 0.0621 | 0.0737 | 0.1169 | 0.1307 | 0.6180 | 0.5779 | 0.0006 | 0.0031 | 0.0043 | 0.0210 | 0.0611 | 0.0945 | 0.0667 | 0.1050 | 0.6436 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 862 | 60 | | 536 | 8372 | 94.9 | 38.62 | 150.81 | 294.15 | 38 | 55 | 70 | 85 | 97 | 109 | 121 | 135 | 146 | 0.0688 | 576 | 0.456 | 105.65 | 21.93 | 2 | 0.7705 | 413 | 0.0025 | 45.30 | 6.078 | 0.1747 | 10500.4 | 1270000 | 163000000 | 21700000000 | 0.3490 | 0.2577 | 0.0000 | 0.0032 | 0.0057 | 0.0000 | 0.0345 | 0.0000 | 0.1149 | 0.0097 | 0.1782 | 0.0968 | 0.1782 | 0.1452 | 0.1322 | 0.1161 | 0.1379 | 0.1613 | 0.2184 | 0.4677 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0137 | 0.0024 | 0.0521 | 0.0471 | 0.0493 | 0.0659 | 0.0548 | 0.0329 | 0.0740 | 0.0776 | 0.7562 | 0.7741 | 0.0000 | 0.0000 | 0.0052 | 0.0000 | 0.0052 | 0.0087 | 0.0209 | 0.0435 | 0.0995 | 0.1130 | 0.0785 | 0.1130 | 0.1099 | 0.1217 | 0.1152 | 0.1739 | 0.5654 | 0.4261 | 0.0000 | 0.0000 | 0.0035 | 0.0142 | 0.0745 | 0.0816 | 0.0780 | 0.0957 | 0.6525 | 15 | 18 | 20 | 22 | 25 | 32 | 64 | 197 | 482 | 0.1543 | 30.36 | 3.816 | 0.6306 | 109258.0 | 124000000 | 171000000000 | 266000000000000 | 0.6017 | 0.0867 | 0.1678 | 0.0032 | 0.3557 | 0.0852 | 0.2550 | 0.2981 | 0.1040 | 0.2618 | 0.0570 | 0.1467 | 0.0336 | 0.1073 | 0.0201 | 0.0442 | 0.0067 | 0.0331 | 0.0000 | 0.0205 | 0.0010 | 0.0004 | 0.0025 | 0.0018 | 0.0029 | 0.0031 | 0.0152 | 0.0161 | 0.0678 | 0.0629 | 0.1130 | 0.0915 | 0.0683 | 0.0683 | 0.1170 | 0.1071 | 0.6123 | 0.6488 | 0.0006 | 0.0006 | 0.0012 | 0.0006 | 0.0069 | 0.0056 | 0.0242 | 0.0311 | 0.0806 | 0.0840 | 0.1163 | 0.1319 | 0.0996 | 0.0989 | 0.1232 | 0.1319 | 0.5475 | 0.5152 | 0.0011 | 0.0021 | 0.0037 | 0.0144 | 0.0880 | 0.1077 | 0.0859 | 0.1189 | 0.5781 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1133 | 155 | | 893 | 1399 | 15.3 | 5.59 | 6.05 | 2.57 | 9 | 11 | 12 | 13 | 14 | 15 | 17 | 19 | 23 | 0.2437 | 341 | 0.631 | 86.21 | 19.03 | 0 | 0.2520 | 225 | 0.0063 | 15.00 | 5.353 | 0.2862 | 266.3 | 5252.12 | 117067 | 2910000 | 0.3793 | 0.2519 | 0.0048 | 0.0028 | 0.0333 | 0.0000 | 0.0643 | 0.0127 | 0.1452 | 0.0325 | 0.1786 | 0.0734 | 0.2262 | 0.0805 | 0.1762 | 0.1427 | 0.1143 | 0.2260 | 0.0571 | 0.4294 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0240 | 0.0059 | 0.0314 | 0.0202 | 0.0569 | 0.0308 | 0.0883 | 0.0403 | 0.1033 | 0.0664 | 0.1856 | 0.1151 | 0.4985 | 0.7212 | 0.0282 | 0.0444 | 0.0726 | 0.0667 | 0.0565 | 0.0963 | 0.0645 | 0.1037 | 0.1089 | 0.0889 | 0.1089 | 0.0963 | 0.1089 | 0.1185 | 0.1573 | 0.1481 | 0.2944 | 0.2370 | 0.0070 | 0.0282 | 0.0446 | 0.0845 | 0.1009 | 0.1056 | 0.1502 | 0.1291 | 0.3498 | 2 | 4 | 4 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0207 | 14.14 | 4.219 | 0.3005 | 43.2 | 342.525 | 2947.43 | 27112.9 | 0.5136 | 0.1528 | 0.0287 | 0.0010 | 0.1396 | 0.0117 | 0.2199 | 0.0321 | 0.2581 | 0.0884 | 0.1893 | 0.1574 | 0.1090 | 0.2235 | 0.0402 | 0.2673 | 0.0134 | 0.1720 | 0.0019 | 0.0466 | 0.0022 | 0.0000 | 0.0151 | 0.0048 | 0.0635 | 0.0032 | 0.1389 | 0.0415 | 0.2099 | 0.0909 | 0.2196 | 0.1085 | 0.2056 | 0.1699 | 0.1044 | 0.2759 | 0.0409 | 0.3054 | 0.1010 | 0.3289 | 0.2241 | 0.3156 | 0.1946 | 0.2089 | 0.1749 | 0.0800 | 0.1626 | 0.0444 | 0.0788 | 0.0222 | 0.0542 | 0.0000 | 0.0099 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0320 | 0.0959 | 0.1337 | 0.2024 | 0.2237 | 0.1787 | 0.0959 | 0.0296 |
| SK-BR-3 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 961 | 83 | | 2742 | 10295 | 256.4 | 210.99 | 5.84 | 2.73 | 85 | 107 | 125 | 146 | 174 | 205 | 260 | 375 | 620 | 0.0768 | 791 | 0.892 | 36.22 | 8.60 | 0 | 0.0317 | 87 | 0.0014 | 48.21 | 6.944 | 0.2535 | 110231.0 | 65700000 | 45700000000 | 34200000000000 | 0.3023 | 0.3121 | 0.0000 | 0.0000 | 0.0068 | 0.0000 | 0.0091 | 0.0000 | 0.0590 | 0.0149 | 0.1791 | 0.0528 | 0.1655 | 0.0916 | 0.1179 | 0.0677 | 0.1088 | 0.1066 | 0.3537 | 0.6663 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0076 | 0.0370 | 0.0242 | 0.0497 | 0.0369 | 0.0416 | 0.0242 | 0.0542 | 0.0445 | 0.8076 | 0.8626 | 0.0015 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0075 | 0.0070 | 0.0330 | 0.0370 | 0.0526 | 0.0546 | 0.0330 | 0.0352 | 0.0691 | 0.0651 | 0.8018 | 0.8011 | 0.0012 | 0.0012 | 0.0000 | 0.0059 | 0.0297 | 0.0547 | 0.0321 | 0.0523 | 0.8228 | 2 | 4 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 0.0175 | 13.89 | 4.460 | 0.2950 | 41.5 | 339.783 | 3128.09 | 31961.6 | 0.5476 | 0.1416 | 0.0210 | 0.0022 | 0.0924 | 0.0062 | 0.1853 | 0.0333 | 0.2319 | 0.0823 | 0.2233 | 0.1544 | 0.1561 | 0.2425 | 0.0700 | 0.2497 | 0.0170 | 0.1701 | 0.0030 | 0.0593 | 0.0012 | 0.0000 | 0.0080 | 0.0010 | 0.0371 | 0.0068 | 0.0981 | 0.0266 | 0.1836 | 0.0573 | 0.2370 | 0.1201 | 0.2176 | 0.2178 | 0.1428 | 0.3119 | 0.0746 | 0.2586 | 0.1311 | 0.2667 | 0.2100 | 0.2515 | 0.2092 | 0.1673 | 0.1698 | 0.1115 | 0.1054 | 0.0630 | 0.0671 | 0.0527 | 0.0519 | 0.0333 | 0.0371 | 0.0339 | 0.0183 | 0.0200 | 0.0124 | 0.0502 | 0.1000 | 0.1483 | 0.1892 | 0.1839 | 0.1558 | 0.0989 | 0.0613 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 742 | 248 | | 1325 | 5484 | 955.8 | 428.77 | 8.01 | 2.97 | 481 | 526 | 610 | 705 | 833 | 1020 | 1224 | 1418 | 1627 | 0.0857 | 470 | 0.902 | 36.72 | 12.08 | 1 | 0.0823 | 109 | 0.0016 | 81.60 | 6.699 | 0.1744 | 1100000.0 | 1440000000 | 2060000000000 | 3.12E+15 | 0.3703 | 0.2538 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0110 | 0.0015 | 0.1801 | 0.0682 | 0.2904 | 0.1091 | 0.1360 | 0.0636 | 0.1324 | 0.1197 | 0.2500 | 0.6348 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0360 | 0.0308 | 0.0596 | 0.0473 | 0.0263 | 0.0226 | 0.0526 | 0.0473 | 0.8241 | 0.8520 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0022 | 0.0128 | 0.0511 | 0.0511 | 0.0644 | 0.0831 | 0.0378 | 0.0511 | 0.0578 | 0.0895 | 0.7867 | 0.7093 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0417 | 0.0609 | 0.0330 | 0.0557 | 0.8070 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 12 | 0.0134 | 9.32 | 4.700 | 0.3378 | 73.0 | 745.296 | 8414.3 | 103808 | 0.4557 | 0.1834 | 0.0246 | 0.0007 | 0.0780 | 0.0051 | 0.1560 | 0.0156 | 0.2275 | 0.0356 | 0.2236 | 0.0749 | 0.1629 | 0.1318 | 0.0948 | 0.2083 | 0.0289 | 0.2962 | 0.0039 | 0.2318 | 0.0045 | 0.0000 | 0.0206 | 0.0000 | 0.0448 | 0.0044 | 0.0775 | 0.0143 | 0.1104 | 0.0457 | 0.1205 | 0.0733 | 0.1415 | 0.1199 | 0.1700 | 0.2262 | 0.3102 | 0.5161 | 0.0910 | 0.1312 | 0.0842 | 0.1131 | 0.0910 | 0.1508 | 0.1045 | 0.1146 | 0.1270 | 0.1071 | 0.1222 | 0.1056 | 0.1283 | 0.1071 | 0.1236 | 0.0920 | 0.1283 | 0.0784 | 0.0246 | 0.0667 | 0.0896 | 0.1051 | 0.0958 | 0.1127 | 0.1221 | 0.1629 | 0.2206 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1226 | 292 | | 1447 | 9024 | 65.1 | 24.28 | 181.44 | 210.82 | 35 | 44 | 51 | 57 | 63 | 69 | 76 | 85 | 96 | 0.0659 | 595 | 0.521 | 83.49 | 16.03 | 5 | 0.1714 | 248 | 0.0021 | 31.10 | 6.361 | 0.2003 | 4823.6 | 400876 | 37000000 | 3760000000 | 0.3867 | 0.2406 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0198 | 0.0028 | 0.0843 | 0.0170 | 0.1802 | 0.0405 | 0.2215 | 0.1008 | 0.1884 | 0.1329 | 0.1818 | 0.1951 | 0.1124 | 0.5108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0016 | 0.0109 | 0.0095 | 0.0465 | 0.0247 | 0.0812 | 0.0366 | 0.0663 | 0.0461 | 0.1238 | 0.0700 | 0.6693 | 0.8115 | 0.0049 | 0.0255 | 0.0099 | 0.0204 | 0.0025 | 0.0510 | 0.0765 | 0.1071 | 0.1284 | 0.1837 | 0.1778 | 0.1735 | 0.1654 | 0.1173 | 0.1407 | 0.1378 | 0.2938 | 0.1837 | 0.0015 | 0.0029 | 0.0059 | 0.0322 | 0.1025 | 0.1259 | 0.1127 | 0.1347 | 0.4817 | 19 | 26 | 41 | 64 | 97 | 142 | 205 | 308 | 477 | 0.0338 | 9.96 | 5.000 | 0.5659 | 77361.5 | 47900000 | 36100000000 | 30600000000000 | 0.5191 | 0.1524 | 0.0220 | 0.0015 | 0.0828 | 0.0094 | 0.1118 | 0.0342 | 0.1577 | 0.0768 | 0.2126 | 0.1412 | 0.1427 | 0.1684 | 0.1228 | 0.1273 | 0.0918 | 0.1446 | 0.0559 | 0.2967 | 0.0006 | 0.0005 | 0.0025 | 0.0012 | 0.0034 | 0.0009 | 0.0104 | 0.0092 | 0.0533 | 0.0431 | 0.0855 | 0.0726 | 0.0676 | 0.0528 | 0.0917 | 0.0820 | 0.6851 | 0.7378 | 0.0008 | 0.0013 | 0.0027 | 0.0022 | 0.0059 | 0.0040 | 0.0164 | 0.0211 | 0.0632 | 0.0723 | 0.1096 | 0.1159 | 0.0780 | 0.0858 | 0.1166 | 0.1204 | 0.6069 | 0.5768 | 0.0003 | 0.0020 | 0.0043 | 0.0143 | 0.0627 | 0.0953 | 0.0720 | 0.1040 | 0.6450 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 854 | 856 | | 7221 | 14570 | 49.4 | 17.53 | 78.00 | 136.28 | 28 | 34 | 38 | 43 | 47 | 52 | 58 | 64 | 73 | 0.0925 | 1347 | 0.564 | 226.82 | 39.32 | 13 | 0.0867 | 626 | 0.0060 | 6.82 | 5.419 | 0.3768 | 2746.4 | 169000 | 11300000 | 819000000 | 0.4385 | 0.1979 | 0.0021 | 0.0002 | 0.0092 | 0.0013 | 0.0509 | 0.0036 | 0.1206 | 0.0209 | 0.1835 | 0.0519 | 0.1998 | 0.1171 | 0.1729 | 0.1192 | 0.1266 | 0.1517 | 0.1344 | 0.5342 | 0.0004 | 0.0000 | 0.0012 | 0.0005 | 0.0037 | 0.0013 | 0.0217 | 0.0112 | 0.0562 | 0.0266 | 0.0864 | 0.0540 | 0.0848 | 0.0579 | 0.1085 | 0.0691 | 0.6371 | 0.7796 | 0.0039 | 0.0097 | 0.0073 | 0.0154 | 0.0194 | 0.0328 | 0.0682 | 0.0936 | 0.1094 | 0.1380 | 0.1510 | 0.1979 | 0.1292 | 0.1342 | 0.1549 | 0.1467 | 0.3567 | 0.2317 | 0.0017 | 0.0026 | 0.0125 | 0.0408 | 0.0755 | 0.1098 | 0.1078 | 0.1329 | 0.5163 | 11 | 13 | 15 | 17 | 20 | 26 | 46 | 104 | 234 | 0.1860 | 10.58 | 3.510 | 0.6862 | 24655.2 | 13200000 | 8940000000 | 7000000000000 | 0.6410 | 0.1101 | 0.1548 | 0.0039 | 0.3289 | 0.0394 | 0.2946 | 0.2229 | 0.1131 | 0.2327 | 0.0565 | 0.2189 | 0.0298 | 0.1433 | 0.0134 | 0.0671 | 0.0074 | 0.0493 | 0.0015 | 0.0224 | 0.0008 | 0.0002 | 0.0008 | 0.0005 | 0.0032 | 0.0053 | 0.0201 | 0.0138 | 0.0823 | 0.0766 | 0.1173 | 0.0994 | 0.0839 | 0.0713 | 0.1284 | 0.1266 | 0.5631 | 0.6063 | 0.0003 | 0.0007 | 0.0023 | 0.0021 | 0.0058 | 0.0053 | 0.0229 | 0.0248 | 0.1011 | 0.1076 | 0.1308 | 0.1522 | 0.0995 | 0.0995 | 0.1485 | 0.1501 | 0.4889 | 0.4577 | 0.0000 | 0.0023 | 0.0053 | 0.0197 | 0.0978 | 0.1169 | 0.0934 | 0.1436 | 0.5211 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1110 | 560 | | 2334 | 4086 | 123.1 | 42.05 | 219.05 | 128.32 | 74 | 87 | 96 | 107 | 117 | 129 | 142 | 157 | 183 | 0.1216 | 497 | 1.080 | 108.23 | 35.38 | 1 | 0.1204 | 281 | 0.0009 | 90.87 | 7.214 | 0.1270 | 16914.4 | 2570000 | 424000000 | 75500000000 | 0.4870 | 0.1611 | 0.0000 | 0.0000 | 0.0062 | 0.0006 | 0.0503 | 0.0006 | 0.1077 | 0.0083 | 0.1877 | 0.0598 | 0.2236 | 0.1374 | 0.1549 | 0.1291 | 0.1251 | 0.1551 | 0.1446 | 0.5091 | 0.0000 | 0.0000 | 0.0013 | 0.0005 | 0.0013 | 0.0000 | 0.0139 | 0.0057 | 0.0606 | 0.0335 | 0.1205 | 0.0746 | 0.0833 | 0.0581 | 0.1091 | 0.0846 | 0.6101 | 0.7430 | 0.0016 | 0.0000 | 0.0049 | 0.0000 | 0.0148 | 0.0256 | 0.0590 | 0.1026 | 0.1426 | 0.1891 | 0.1672 | 0.1987 | 0.1344 | 0.1218 | 0.1656 | 0.1346 | 0.3098 | 0.2276 | 0.0000 | 0.0019 | 0.0104 | 0.0321 | 0.0888 | 0.1671 | 0.1048 | 0.1398 | 0.4551 | 74 | 103 | 134 | 163 | 195 | 230 | 276 | 327 | 396 | 0.0027 | 23.43 | 6.329 | 0.2976 | 64441.3 | 23200000 | 9650000000 | 4520000000000 | 0.5232 | 0.1346 | 0.0093 | 0.0010 | 0.0558 | 0.0031 | 0.1767 | 0.0135 | 0.1787 | 0.0556 | 0.1911 | 0.1329 | 0.1560 | 0.1989 | 0.1188 | 0.1848 | 0.0692 | 0.1776 | 0.0444 | 0.2326 | 0.0004 | 0.0003 | 0.0009 | 0.0007 | 0.0044 | 0.0031 | 0.0126 | 0.0097 | 0.0566 | 0.0384 | 0.1111 | 0.0746 | 0.0910 | 0.0695 | 0.1324 | 0.1126 | 0.5906 | 0.6911 | 0.0015 | 0.0041 | 0.0068 | 0.0021 | 0.0090 | 0.0155 | 0.0384 | 0.0671 | 0.1032 | 0.1405 | 0.1800 | 0.1736 | 0.1122 | 0.1395 | 0.1611 | 0.1736 | 0.3878 | 0.2841 | 0.0000 | 0.0023 | 0.0051 | 0.0277 | 0.0779 | 0.1429 | 0.1107 | 0.1440 | 0.4896 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1272 | 883 | | 1150 | 8995 | 239.8 | 65.75 | 123.62 | 67.46 | 158 | 173 | 191 | 209 | 232 | 258 | 286 | 306 | 330 | 0.0845 | 760 | 0.982 | 95.52 | 25.18 | 3 | 0.2000 | 230 | 0.0013 | 67.56 | 6.741 | 0.1434 | 61808.3 | 17000000 | 4910000000 | 1480000000000 | 0.4669 | 0.1629 | 0.0043 | 0.0010 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0469 | 0.0068 | 0.1919 | 0.0476 | 0.2751 | 0.1322 | 0.1663 | 0.0787 | 0.1215 | 0.1351 | 0.1919 | 0.5986 | 0.0013 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0150 | 0.0045 | 0.0614 | 0.0303 | 0.0852 | 0.1025 | 0.0576 | 0.0357 | 0.0827 | 0.0677 | 0.6967 | 0.7585 | 0.0000 | 0.0108 | 0.0000 | 0.0323 | 0.0000 | 0.0538 | 0.0274 | 0.1720 | 0.1337 | 0.1398 | 0.1125 | 0.1613 | 0.1155 | 0.1720 | 0.1763 | 0.1075 | 0.4347 | 0.1505 | 0.0000 | 0.0000 | 0.0019 | 0.0242 | 0.0576 | 0.1022 | 0.0762 | 0.0929 | 0.6450 | 49 | 64 | 78 | 92 | 110 | 130 | 153 | 178 | 216 | 0.0036 | 19.57 | 6.129 | 0.3167 | 19833.3 | 3880000 | 886000000 | 230000000000 | 0.5219 | 0.1301 | 0.0186 | 0.0026 | 0.0971 | 0.0077 | 0.1631 | 0.0208 | 0.1817 | 0.0612 | 0.1719 | 0.1229 | 0.1524 | 0.1718 | 0.1115 | 0.1593 | 0.0678 | 0.1860 | 0.0358 | 0.2677 | 0.0012 | 0.0012 | 0.0034 | 0.0023 | 0.0078 | 0.0055 | 0.0254 | 0.0158 | 0.0730 | 0.0453 | 0.1045 | 0.0772 | 0.1015 | 0.0721 | 0.1389 | 0.1101 | 0.5443 | 0.6705 | 0.0011 | 0.0082 | 0.0102 | 0.0169 | 0.0186 | 0.0416 | 0.0629 | 0.0914 | 0.1265 | 0.1422 | 0.1757 | 0.1792 | 0.1409 | 0.1555 | 0.1452 | 0.1247 | 0.3188 | 0.2402 | 0.0018 | 0.0043 | 0.0128 | 0.0337 | 0.0856 | 0.1573 | 0.1206 | 0.1418 | 0.4421 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1111 | 218 | | 2639 | 15470 | 519.2 | 295.40 | 7.24 | 2.89 | 158 | 199 | 267 | 362 | 461 | 629 | 752 | 861 | 946 | 0.0584 | 904 | 1.018 | 61.29 | 17.26 | 1 | 0.0561 | 148 | 0.0024 | 14.54 | 6.516 | 0.3332 | 356819.0 | 281000000 | 236000000000 | 206000000000000 | 0.3341 | 0.2839 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0102 | 0.0024 | 0.0332 | 0.0071 | 0.1969 | 0.0756 | 0.2123 | 0.1263 | 0.1637 | 0.0862 | 0.1867 | 0.1098 | 0.1944 | 0.5927 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0012 | 0.0014 | 0.0018 | 0.0254 | 0.0257 | 0.0357 | 0.0293 | 0.0254 | 0.0246 | 0.0460 | 0.0334 | 0.8640 | 0.8841 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0019 | 0.0058 | 0.0319 | 0.0255 | 0.0432 | 0.0638 | 0.0244 | 0.0290 | 0.0413 | 0.0348 | 0.8573 | 0.8399 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0262 | 0.0467 | 0.0213 | 0.0344 | 0.8705 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 11 | 0.1427 | 0.45 | 0.999 | 0.4303 | 60.8 | 577.971 | 6348.95 | 88018.5 | 0.4997 | 0.1587 | 0.0222 | 0.0021 | 0.0836 | 0.0094 | 0.1754 | 0.0371 | 0.2398 | 0.0855 | 0.2237 | 0.1719 | 0.1606 | 0.2362 | 0.0727 | 0.2550 | 0.0202 | 0.1567 | 0.0017 | 0.0461 | 0.0016 | 0.0002 | 0.0068 | 0.0010 | 0.0283 | 0.0046 | 0.0631 | 0.0161 | 0.1191 | 0.0465 | 0.1675 | 0.1004 | 0.2085 | 0.1888 | 0.2349 | 0.2956 | 0.1701 | 0.3468 | 0.0733 | 0.1314 | 0.1319 | 0.2046 | 0.1568 | 0.2008 | 0.1465 | 0.1602 | 0.1442 | 0.1368 | 0.1434 | 0.0882 | 0.1027 | 0.0454 | 0.0718 | 0.0227 | 0.0294 | 0.0099 | 0.0130 | 0.0314 | 0.0618 | 0.0977 | 0.1424 | 0.1625 | 0.1874 | 0.1808 | 0.1230 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1017 | 174 | | 1248 | 1851 | 214.5 | 155.04 | 45.32 | 44.12 | 105 | 122 | 135 | 145 | 159 | 175 | 196 | 246 | 453 | 0.2150 | 398 | 0.886 | 138.05 | 45.25 | 2 | 0.3045 | 380 | 0.0030 | 54.71 | 6.166 | 0.2695 | 70037.8 | 33300000 | 19600000000 | 12700000000000 | 0.3408 | 0.2642 | 0.0000 | 0.0014 | 0.0105 | 0.0000 | 0.0592 | 0.0027 | 0.0941 | 0.0095 | 0.2056 | 0.0846 | 0.1638 | 0.1419 | 0.0906 | 0.1132 | 0.1289 | 0.1050 | 0.2474 | 0.5416 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0076 | 0.0011 | 0.0191 | 0.0085 | 0.0841 | 0.0512 | 0.1071 | 0.0800 | 0.0650 | 0.0597 | 0.1071 | 0.0778 | 0.6099 | 0.7207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0169 | 0.0098 | 0.0805 | 0.1073 | 0.1059 | 0.1024 | 0.0551 | 0.0488 | 0.0975 | 0.1024 | 0.6441 | 0.6293 | 0.0032 | 0.0097 | 0.0097 | 0.0130 | 0.0909 | 0.0942 | 0.0390 | 0.1039 | 0.6364 | 20 | 22 | 25 | 27 | 30 | 34 | 39 | 51 | 87 | 0.1634 | 0.96 | 2.528 | 0.7872 | 4000.0 | 623754 | 127000000 | 29000000000 | 0.5672 | 0.0956 | 0.0344 | 0.0145 | 0.0875 | 0.0190 | 0.1375 | 0.0335 | 0.1313 | 0.0760 | 0.1906 | 0.1229 | 0.2000 | 0.1508 | 0.1156 | 0.1620 | 0.0688 | 0.1721 | 0.0344 | 0.2492 | 0.0106 | 0.0111 | 0.0257 | 0.0146 | 0.0287 | 0.0231 | 0.0332 | 0.0446 | 0.0861 | 0.0788 | 0.1344 | 0.0925 | 0.1239 | 0.1071 | 0.1360 | 0.1500 | 0.4215 | 0.4781 | 0.0029 | 0.0037 | 0.0088 | 0.0368 | 0.0205 | 0.0404 | 0.0526 | 0.0772 | 0.1404 | 0.0919 | 0.1725 | 0.1287 | 0.1023 | 0.1213 | 0.1287 | 0.1103 | 0.3713 | 0.3897 | 0.0022 | 0.0155 | 0.0310 | 0.0376 | 0.1062 | 0.1372 | 0.1261 | 0.1482 | 0.3960 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 438 | 881 | | 789 | 8063 | 74.1 | 31.85 | 47.97 | 131.71 | 30 | 40 | 55 | 65 | 73 | 81 | 92 | 101 | 116 | 0.0633 | 510 | 0.386 | 127.58 | 22.47 | 2 | 0.5982 | 472 | 0.0024 | 38.72 | 6.180 | 0.1858 | 6504.0 | 641928 | 68900000 | 7880000000 | 0.3632 | 0.2507 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0538 | 0.0043 | 0.1000 | 0.0172 | 0.2115 | 0.0948 | 0.1808 | 0.1401 | 0.1846 | 0.1185 | 0.1692 | 0.1789 | 0.0962 | 0.4461 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0135 | 0.0049 | 0.0558 | 0.0395 | 0.0673 | 0.0543 | 0.0635 | 0.0329 | 0.0885 | 0.0625 | 0.7115 | 0.8059 | 0.0000 | 0.0000 | 0.0154 | 0.0139 | 0.0077 | 0.0625 | 0.0346 | 0.0694 | 0.0962 | 0.1319 | 0.1269 | 0.1667 | 0.1038 | 0.1528 | 0.1692 | 0.1250 | 0.4462 | 0.2778 | 0.0026 | 0.0000 | 0.0026 | 0.0179 | 0.0742 | 0.0818 | 0.1023 | 0.1560 | 0.5627 | 11 | 13 | 15 | 16 | 18 | 20 | 22 | 26 | 61 | 0.4823 | 4.88 | 1.769 | 0.8585 | 19647.5 | 17700000 | 20000000000 | 25500000000000 | 0.6771 | 0.1020 | 0.0533 | 0.0311 | 0.1557 | 0.0251 | 0.2172 | 0.0621 | 0.2377 | 0.0932 | 0.2008 | 0.1657 | 0.0820 | 0.2027 | 0.0287 | 0.1686 | 0.0164 | 0.1198 | 0.0082 | 0.1317 | 0.0000 | 0.0147 | 0.0009 | 0.0077 | 0.0046 | 0.0105 | 0.0352 | 0.0252 | 0.0897 | 0.0617 | 0.1175 | 0.0870 | 0.1027 | 0.1024 | 0.1036 | 0.1080 | 0.5458 | 0.5827 | 0.0012 | 0.0013 | 0.0036 | 0.0027 | 0.0060 | 0.0080 | 0.0239 | 0.0213 | 0.1004 | 0.1120 | 0.1470 | 0.1600 | 0.1016 | 0.0973 | 0.1147 | 0.1307 | 0.5018 | 0.4667 | 0.0000 | 0.0011 | 0.0074 | 0.0253 | 0.1077 | 0.1267 | 0.0940 | 0.1109 | 0.5269 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 321 | 840 | | 426 | 368 | 95.5 | 47.70 | 697.86 | 488.70 | 32 | 42 | 60 | 77 | 96 | 112 | 127 | 143 | 162 | 0.4701 | 173 | 0.664 | 93.61 | 19.80 | 1 | 0.5915 | 252 | 0.0030 | 67.57 | 5.878 | 0.1356 | 11384.7 | 1540000 | 222000000 | 33700000000 | 0.2891 | 0.3236 | 0.0000 | 0.0000 | 0.0000 | 0.0052 | 0.1616 | 0.0000 | 0.1919 | 0.0155 | 0.2121 | 0.1503 | 0.1515 | 0.2591 | 0.2020 | 0.1295 | 0.0404 | 0.1969 | 0.0404 | 0.2435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0077 | 0.0032 | 0.0575 | 0.0583 | 0.0996 | 0.0841 | 0.0421 | 0.0388 | 0.0613 | 0.0680 | 0.7318 | 0.7476 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0247 | 0.0517 | 0.0802 | 0.0862 | 0.1049 | 0.1897 | 0.0988 | 0.1207 | 0.1420 | 0.1034 | 0.5432 | 0.4483 | 0.0000 | 0.0000 | 0.0000 | 0.0140 | 0.0698 | 0.0930 | 0.0512 | 0.0884 | 0.6837 | 135 | 270 | 399 | 510 | 616 | 717 | 852 | 1036 | 1456 | 0.0038 | 170.10 | 5.726 | 0.1849 | 725176.0 | 955000000 | 1470000000000 | 2.5E+15 | 0.4289 | 0.2015 | 0.0465 | 0.0000 | 0.1860 | 0.0120 | 0.2558 | 0.0663 | 0.1279 | 0.1205 | 0.1047 | 0.2651 | 0.1395 | 0.2108 | 0.0814 | 0.1566 | 0.0581 | 0.0904 | 0.0000 | 0.0783 | 0.0050 | 0.0000 | 0.0300 | 0.0000 | 0.0550 | 0.0405 | 0.0750 | 0.0526 | 0.1250 | 0.1579 | 0.1600 | 0.1741 | 0.1700 | 0.1660 | 0.1450 | 0.1296 | 0.2350 | 0.2794 | 0.0439 | 0.0000 | 0.0351 | 0.0000 | 0.0263 | 0.0864 | 0.1228 | 0.0864 | 0.1053 | 0.1605 | 0.2193 | 0.1235 | 0.0965 | 0.1111 | 0.0965 | 0.1358 | 0.2544 | 0.2963 | 0.0132 | 0.0395 | 0.0724 | 0.0921 | 0.1645 | 0.1579 | 0.1382 | 0.0921 | 0.2303 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 |